UNIVERSITY OF MICHIGAN
A director and six charter faculty members have been named for the new Life Sciences Institute, which is one year away from completion. Built around a "lab without walls" concept to encourage collaboration, the institute will target three overlapping areas: genetics, genomics, and proteomics; molecular and cellular biology; and structural, chemical, and computational biology.
Alan R. Saltiel, John Jacob Abel Collegiate Professor in the Life Sciences and professor of internal medicine and physiology, will be the institute's director. He is a recognized authority on diabetes, obesity, and cellular signaling. He spent much of his career in private-sector pharmaceutical work, most recently with Warner-Lambert/Parke-Davis. Saltiel joined the institute in March 2001 as its first faculty member and has served as the institute's associate director. He holds a Ph.D. in biochemistry from the University of North Carolina, Chapel Hill.
Carol A. Fierke, professor of chemistry and biological chemistry, studies enzymes. Her lab is currently focusing on zinc and the role it plays in chemical catalysis and regulation, investigating an enzyme that puts fat-based "tags" onto proteins to direct them from the cell's interior to its outer membrane, and examining enzymes that catalyze key metabolic reactions in bacteria. Fierke earned a Ph.D. in biochemistry from Brandeis University, Waltham, Mass.
David Ginsburg, Howard Hughes Medical Institute investigator and Warner-Lambert/Parke-Davis Professor of Genetics & Internal Medicine, is a physician specializing in blood disorders and genetics. He is studying human families with bleeding disorders such as hemophilia and mice with genetic "knock-outs" to tease apart the complex interactions of biomolecules that control the clotting response. Ginsburg received an M.D. from Duke University.
Gary D. Glick, Werner E. Bachmann Collegiate Professor of Chemistry and professor of biological chemistry, uses the tools of synthetic chemistry to develop a deeper understanding of cellular biology. He is looking at the structure, folding, and dynamics of DNA and RNA, as well as exploring immune system proteins that bind to DNA in inflammatory diseases like systemic lupus erythematosus and rheumatoid arthritis. Glick earned a Ph.D. in synthetic organic chemistry from Columbia University.
Daniel J. Klionsky, professor of molecular, cellular, and developmental biology and biological chemistry, uses baker's yeast as a model organism to study how proteins are moved around the cell with great specificity, as well as how organelles develop and do their work. Klionsky's work also explores "autophagy," the main protein disassembly and recycling system inside the cell, and how it responds to starvation conditions by cannibalizing parts of the cell. Klionsky holds a Ph.D. in biological sciences from Stanford University.
John B. Lowe, Warner-Lambert/Parke-Davis Professor of Medicine, professor of pathology, and Howard Hughes Medical Institute investigator, has isolated genes that control the assembly of complex carbohydrates and used the genes to uncover functions for these molecules in the immune system. Lowe continues to explore complex carbohydrate assembly and function using cells grown in the laboratory and genetically altered mice. Lowe has an M.D. from the University of Utah College of Medicine, Salt Lake City.
Rowena G. Matthews is the G. Robert Greenberg Professor of Biological Chemistry, a senior research scientist in the Biophysics Research Division, and a member of the National Academy of Sciences. She studies vitamins and their role in the chemical reactions of the cell. Matthews' work on riboflavin and folic acid has helped determine how homocysteine levels can be controlled, contributing to the recommendation that all people--especially pregnant women--consume more folic acid. Matthews earned a Ph.D. in biophysics from the University of Michigan, Ann Arbor.
NORTH CAROLINA BIOTECHNOLOGY CENTER
Research Triangle Park, N.C.
Leslie M. Alexandre has been named president and CEO. She was assistant director for industrial relations at the National Cancer Institute, which she joined in 1999. Prior to that, she was vice president of corporate affairs and marketing at the biotechnology company Oncormed. Alexandre has experience working as a government affairs representative for health policy at EDS, holding senior policy positions with two U.S. senators, and developing a health care consulting practice.
Gerald K. Carlson, formerly a senior vice president of Ecolab, has been named CEO of Philipp Brothers Chemicals, Fort Lee, N.J. His 32-year career with Ecolab included responsibilities for running international operations, the U.S. institutional business, and corporate development.
Mary E. Lawson has been appointed eastern regional manager for the electronics business at Glen Rock, Pa.-based Adhesives Research Inc. She spent 11 years with SPI Polyols Inc. (formerly ICI Polyols) in sales management, technical service management, and direct sales positions. Before that, she worked as a chemist in ICI's specialty chemicals division. Lawson began her career in 1981 as a chemist with Eastman Kodak. She holds a bachelor's degree in chemistry from Duquesne University and a master's degree in materials science and engineering from Rochester Institute of Technology.
Paul R. Loconto has begun work as a laboratory scientist/specialist at the Michigan Department of Community Health, Division of Chemistry & Toxicology, in Lansing. This appointment follows more than nine years as a laboratory manager at Michigan State University, East Lansing. He is involved in developing a strategic plan for a statewide biomonitoring initiative. Loconto earned a Ph.D. in analytical chemistry from the University of Massachusetts, Lowell (formerly the University of Lowell).
Patrick J. Murin has joined Houston-based CDM as a vice president. He will lead the development of air quality services to industry along the Gulf Coast. Murin has 25 years of experience in diverse chemical and environmental engineering projects. As president of Waid & Associates, he led teams providing air quality services to petrochemical, oil and gas, manufacturing, waste management, and high-tech facilities along the Gulf Coast. Murin graduated from Carnegie Mellon University, Pittsburgh, with a B.S. in chemical engineering and a B.S. in engineering and public policy.
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