C&EN: COVER STORY - CHIRAL ROUNDUP- STEADY RISE

June 10, 2002
Volume 80, Number 23
CENEAR 80 23 pp. 43-50
ISSN 0009-2347

STEADY RISE
Worldwide sales of single-enantiomer drugs approach $150 billion

2000 SINGLE-ENANTIOMER 2001^a SINGLE-ENANTIOMER

$ BILLIONS TOTAL MARKET SALES MARKET SHARE TOTAL MARKET SALES MARKET SHARE

Antibiotics/antifungals $31.7 $25.9 82% $33.0 $26.9 82%

Hematology 15.4 12.0 78 16.5 13.5 82

Cancer 15.6 12.2 78 17.0 13.3 78

Hormones/endocrinology 22.0 15.2 69 26.0 18.5 71

Cardiovascular 46.6 27.7 59 50.0 30.2 60

Vaccines 7.3 3.4 47 8.5 4.3 51

Antivirals 19.1 5.9 31 20.0 6.1 31

Ophthalmic 7.4 2.3 31 8.0 2.4 30

Central nervous system 53.9 9.3 17 55.0 10.5 19

Respiratory 40.5 6.5 16 42.0 7.9 19

Gastrointestinal 47.2 4.2 9 50.0 5.4 11

Dermatology 18.4 1.3 7 18.5 1.2 6

Analgesics 23.0 1.2 5 23.5 1.2 5

Others 41.9 5.9 14 42.0 5.8 14

TOTAL $390.0 $133.0 34% $410.0 $147.2 36%

a Preliminary estimates. SOURCE: Technology Catalysts International

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STEADY RISE Worldwide sales of single-enantiomer drugs approach $150 billion
	2000 SINGLE-ENANTIOMER			2001^a SINGLE-ENANTIOMER
$ BILLIONS	TOTAL MARKET	SALES	MARKET SHARE	TOTAL MARKET	SALES	MARKET SHARE
Antibiotics/antifungals	$31.7	$25.9	82%	$33.0	$26.9	82%
Hematology	15.4	12.0	78	16.5	13.5	82
Cancer	15.6	12.2	78	17.0	13.3	78
Hormones/endocrinology	22.0	15.2	69	26.0	18.5	71
Cardiovascular	46.6	27.7	59	50.0	30.2	60
Vaccines	7.3	3.4	47	8.5	4.3	51
Antivirals	19.1	5.9	31	20.0	6.1	31
Ophthalmic	7.4	2.3	31	8.0	2.4	30
Central nervous system	53.9	9.3	17	55.0	10.5	19
Respiratory	40.5	6.5	16	42.0	7.9	19
Gastrointestinal	47.2	4.2	9	50.0	5.4	11
Dermatology	18.4	1.3	7	18.5	1.2	6
Analgesics	23.0	1.2	5	23.5	1.2	5
Others	41.9	5.9	14	42.0	5.8	14
TOTAL	$390.0	$133.0	34%	$410.0	$147.2	36%
a Preliminary estimates. SOURCE: Technology Catalysts International