November 11, 2002
Volume 80, Number 45
CENEAR 80 45 p. 44
ISSN 0009-2347


BIODIVERSITY Porco, coprincipal investigator James Panek, and coworkers at Boston University's new CMLD facility used a distannoxane transesterification catalyst to cyclodimerize in a single step an amino acid- and polyketide-containing hydroxy ester monomer to a 22-member macrodiolide--a compound that approaches the complexity of macrolide and macrodiolide antibiotics.



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