November 11, 2002
Volume 80, Number 45
CENEAR 80 45 p. 50
ISSN 0009-2347


COMBI CARBS Seeberger and coworkers are developing an automated parallel synthesis of heparin-like glycosaminoglycans. Each of four glucosamines is added to a glucuronic or iduronic acid, forming eight disaccharides. The disaccharides are modified and combined, and the resulting oligosaccharides are deprotected and sulfated.
ADAPTED FROM SEEBERGER ET AL., CHEMISTRY--A EUROPEAN JOURNAL (IN PRESS)



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