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December 20, 2010

Coverstory: Chemical Year In Review

C&EN highlights the major research achievements of 2010. (pp. 13-17)

Coverstory: C&EN Revisits 2000

A decade ago, in its annual Chemistry Highlights feature, now called Chemical Year in Review, C&EN looked at some of that year's key research advances in chemistry. Now, C&EN reporters have revisited six of those highlighted discoveries to see what became of them. (pp. 18-20)

Self-Assembling 3-D Electronics

(p. 18)

Targeting Genes With 'Zinc Fingers'

(p. 18)

Functionalized Nanoparticles For Clinical Diagnostics

(p. 19)

Catalytic Reaction Activates Alkanes

(p. 19)

High-Speed Organic Electro-Optics

(p. 20)

Fluoropolymer Processing Breakthrough

(p. 20)

December 13, 2010

Coverstory: Chemistry In The Spotlight

National Chemistry Week demystifies the role of chemistry in movies and on television. (pp. 14-21)

December 6, 2010

Coverstory: Battening The Hatches

Sailing toward the long-dreaded 'patent cliff,' drug firms positioned themselves for a new world of science and business in 2010. (pp. 9-13)

November 29, 2010

Coverstory: Close Quarters

Crowded conditions such as those in cells can affect proteins' structure, function, and activity. (pp. 9-13)

November 22, 2010

Coverstory: Used-Instrument Market

Start-ups and other small firms stock their labs with surplus equipment being resold from pharma closures. (pp. 11-15)

November 15, 2010

Coverstory: The Eastern Advantage

Dye and pigment producers accelerate departure from the West for the rapidly industrializing Asia-Pacific region. (pp. 13-16)

November 8, 2010

Coverstory: Opening The Medicine Cabinet

Pfizer's deal with Washington University signals reduced secretiveness among drug firms. (pp. 14-20)

November 1, 2010

Coverstory: Hint Of Hope

Job outlook for 2011 will likely be similar to 2010's, perhaps even slightly better. (p. 37)

Cautiously Optimistic

In the wake of the recession, employers are poised to slowly and selectively hire. (pp. 38-42)

Making Labs Work Magically Well

Lab and stockroom managers have essential jobs with diverse responsibilities. (pp. 43-45)

Wanted: Role Models

Mentors can help women scientists of color achieve success in their careers. (pp. 46-47)

October 25, 2010

Coverstory: The Un-Rankings

Chemistry graduate programs seek meaning in long-awaited assessment. (pp. 12-17)

Methodology Explained: What's The Difference Between R And S, Anyway?

(p. 14)

View From The Trenches: Students Don't View New Assessment As Critical

(p. 16)

October 18, 2010

Coverstory: Metallocenes Rise Again

The advanced polymer catalysts got off to a slower than expected start, but momentum in the marketplace is now steady. (pp. 10-16)

October 11, 2010

Coverstory: Fighting Friction

In the battle to overcome resistance between surfaces, performance materials improve energy efficiency and help critical components last longer. (pp. 14-17)

October 4, 2010

Coverstory: Chemistry Energizes China

China's quest to develop innovative energy solutions represents a huge opportunity for foreign chemical and materials makers. (pp. 10-16)

September 27, 2010

Coverstory: Genotoxic Impurities

Faced with new guidelines that many find constraining, pharmaceutical manufacturers are seeking ways to avoid or reduce harmful contaminants in drugs. (pp. 16-26)

Detecting Low-Level Impurities

Controlling genotoxic impurities means finding the analytical method best suited to the task. (pp. 27-29)

September 20, 2010

Coverstory: Raman Heads For The Clinic

Vibrational spectroscopy technique may someday be used to diagnose a variety of diseases. (pp. 8-12)

September 13, 2010

Coverstory: Science Education Trends

Demand grows for assessment of education projects; U.S. professors set up shop abroad. (p. 47)

Measuring Success

Funding agencies are pushing for more data to prove that investing in chemical education innovation is paying off. (pp. 48-52)

An Office Across The Ocean

Seizing unique opportunities, U.S. professors set up shop abroad. (pp. 53-54)

September 6, 2010

Coverstory: From A Teaspoon To A Ton

ACS Meeting News: Process chemists master the task of scaled-up pharmaceutical synthesis. (pp. 9-12)

August 30, 2010

Coverstory: Securing The Supply Of Rare Earths

Green-energy and high-tech industries grow anxious over China's monopoly on these valuable resources. (pp. 9-12)

August 23, 2010

Coverstory: The Power Of Plastic

Polymer- and organic-molecule-based solar cells show promise as low-cost power generators. (pp. 12-16)

August 16, 2010

Coverstory: To Clot, Or Not

Anticoagulants in the pipeline may overcome the drawbacks of well-entrenched drugs. (pp. 15-22)

August 9, 2010

Coverstory: Monitoring Greenhouse Gases

Academia and government are avid purchasers of greenhouse gas measurement tools, but industry is slow to catch on. (pp. 10-13)

August 2, 2010

Coverstory: A Green Supply Chain

Manufacturers of consumer products go the distance to source sustainable ingredients. (pp. 16-22)

July 26, 2010

Coverstory: Global Top 50

Firms in 2009 saw solid profitability in the face of plummeting sales; BASF claims top spot for seventh straight year. (pp. 13-16)

July 19, 2010

Coverstory: Filling Nanotech Jobs

Initiatives to educate and employ workers try to find a footing as nanotechnology evolves. (pp. 10-16)

July 12, 2010

Coverstory: Electronic Materials

Buoyed by the proliferation of high-tech gadgets, the electronics industry rebounds from last year's deep downturn. (p. 11)

Chemistry Matters To Chip Makers

As advanced electronic components become complex, materials suppliers find new opportunities. (pp. 12-15)

Smooth Success

Chemical mechanical planarization is becoming indispensable in chip-making. (pp. 16-18)

E-Readers In Color

Developers of display technology try to break out of black and white. (p. 19)

July 5, 2010

Coverstory: Facts & Figures Of The Chemical Industry

The fortunes of the chemical industry continued to decline in 2009 while the recovery took its time. (p. 33)

Industry Adapts To Era Of Low Demand

Chemical firms cut costs and lowered expectations during a rough year for finances. (pp. 34-49)

Industry Slashes Thousands Of Jobs

Employment shrank significantly in europe and the U.S. but held steady in Japan. (pp. 50-53)

Output Declines In U.S., Europe

The recession dragged down chemical production in most regions, but Taiwan and China showed strength. (pp. 54-62)

Economic Downturn Hobbles Commerce

Chemical trade among most regions dropped significantly in 2009 as overall demand plunged. (pp. 64-67)

June 28, 2010

Coverstory: Expanding Safety Training

Schools are exploring a variety of ways to augment laboratory safety instruction for undergraduate students. (pp. 14-20)

Curriculum Resources: A Textbook For Safety

(pp. 17)

Personal Protection: Whither Lab Coats?

(pp. 18-19)

June 21, 2010

Coverstory: High-Res Mass Spec

Mass spectrometry users have more choices for high resolving power, from conventional ion cyclotron resonance to newer time of flight. (pp. 10-15)

June 14, 2010

Coverstory: BP's Ever-Growing Oil Spill

Environmental disaster in the Gulf of Mexico Reveals U.S.'s inability to plan for, control, and clean up oil spills in deep waters. (pp. 15-24)

Politics

President, Some Members Of Congress Hope BP Spill Will Invigorate Energy Legislation Push. (p. 18)

Unwelcome Spotlight

Oil Spill Leads To Fame And Fury For Makers Of Dispersant Chemicals. (p. 22)

Crowd-Sourced Chemistry

Scientists Use Social Networking To Study Spill. (p. 24)

Chronology Of A Catastrophe

(pp. 16-17)

June 7, 2010

Coverstory: Research Recalibrated

The spending race is over in pharmaceutical R&D, with companies now focused on doing more with less. (pp. 13-18)

May 31, 2010

Coverstory: Finding Solutions

Custom manufacturers take on drug solubility issues to help pharmaceutical firms move products through development. (pp. 13-18)

Solubility Solutions: Formulation Routes To Improve Solubility

(pp. 17)

Nicer Than Needles

Delivering biologic drugs orally, instead of by injection, calls for tricking the human body. (pp. 27-30)

May 24, 2010

Coverstory: LIMS In The Cloud

Laboratory information management system software for small users makes maximum use of the Internet. (pp. 12-16)

May 17, 2010

Coverstory: Preserving Cosmetics

Fear of potential carcinogens in personal care products plagues cosmetic ingredients makers. (pp. 13-16)

May 10, 2010

Coverstory: Lisa P. Jackson

EPA administrator is blazing trails, from regulating greenhouse gas emissions to reforming chemical management policies. (pp. 14-18)

May 3, 2010

Coverstory: The Waiting Game

In the next year, the expected approval of small molecules targeting hepatitis C will usher in a new era in treatment. (pp. 12-17)

Alternative Interferons

Small molecules aren't the only new drugs in development to treat hepatitis C. (WEB EXCLUSIVE)

April 26, 2010

Coverstory: Francis S. Collins

NIH's new director discusses challenges and opportunities arising from health care reform, stimulus spending, and more. (pp. 12-18)

April 19, 2010

Coverstory: The Paper Chase

With the help of specialty chemicals, papermakers seek endless recycling of scarce fibers. (pp. 13-17)

Wastewater Treatment

British start-up Arvia tests its technology at a recycled-paper mill. (WEB EXCLUSIVE)

April 12, 2010

Coverstory: Leading DuPont

After a difficult first year as CEO, Ellen Kullman sets the stage for growth. (pp. 10-13)

April 5, 2010

Coverstory: The Amyloid Question

Alzheimer's researchers will soon know whether blocking amyloid-β can slow down the debilitating disease. (pp. 12-17)

'Beta Testing'

ACS Meeting News: Using chemistry tools to refine an Alzheimer's drug candidate. (p. 14)

The Dimebon Debacle

Medivation and Pfizer salvage what they can from the failure of a large Phase III trial for a promising Alzheimer's drug. (WEB EXCLUSIVE)

March 29, 2010

Coverstory: Pittcon 2010

At Pittcon 2010, hints of an instrument industry upturn. (pp. 27-31)

Probing Nanotoxicity

Analytical methods provide insight into hazards of nanomaterials. (pp. 32-34)

Doubling Up On Mass Analysis

Coupling ion mobility spectrometry with mass spec provides sensitivity to analyte mass, charge, and shape. (pp. 35-37)

Instruments On Display

C&EN features Pittcon Editors' Award winners and other notables. (pp. 38-41)

Honors And Awards

Pittcon recognizes achievements in analytical chemistry and applied spectroscopy. (pp. 42-43)

March 22, 2010

Coverstory: Priestley Medalist

Richard Zare receives the 2010 award for applying lasers, as well as creativity and enthusiasm, to molecular research. (pp. 14-18)

Fostering Creativity

(pp. 19-21)

March 15, 2010

Coverstory: Pharma Outsourcing

Relationships between drug companies and chemistry outsourcing partners can span years, even decades. (p. 15)

Patently Right Process Chemistry

Case Study #1: Cytokinetics turns to Irix for help with a tough synthesis. (pp. 16-19)

Loyal Steward Of A Small Molecule

Case Study #2: For over 25 years, Regis has supplied 4-aminopyridine to successive stakeholders for a new multiple sclerosis drug. (pp. 21-23)

More Than A Supplier

Case Study #3: BioVectra seeks greater returns by partnering with Taxolog and Sandoz on a generic cancer drug. (pp. 25-27)

March 8, 2010

Coverstory: Nifty At Fifty

Five decades of laser technology shine light on chemistry fundamentals. (pp. 13-17)

Skyward View

Molecular Dynamics In Real Time

Ultrafast Structural Dynamics Of Biomolecules

Molecules At Surfaces And Interfaces

Electron Dynamics

A View Inside Tissues And Cells

Laser Innovation: Fiber Lasers Bring The Fight

Brief Chronicle Of The Laser

March 1, 2010

Coverstory: Inside The Beauty Lab

In pursuit of innovative products, L’Oréal R&D scientists address beauty 'from the cell to the gesture'. (pp. 17-22)

Coverstory: Treading Lighter

L’Oréal is increasing its commitment to sustainability when developing new ingredients (Web Exclusive)

February 22, 2010

Coverstory: Cracking The Tough Ones

Drug firms hope to accelerate their quest for evasive cures through partnerships. (pp. 12-18)

February 15, 2010

Coverstory: Federal Budget 2011

President Obama shows continued support for basic R&D. (pp. 16-27)

February 8, 2010

Coverstory: Custom Chemicals

After struggling through 2009, contract manufacturers are honing their strategies and hoping for a better 2010. (pp. 15-20)

Coverstory: Taking Over Big Pharma Plants

For better or worse, pharma chemical suppliers are repurposing former drug company plants as custom manufacturing facilities.(pp. 21-26)

February 1, 2010

Coverstory: Fluorochemicals Go Short

Shorter perfluoroalkyl chain lengths improve environmental profile of versatile stain-, grease-, and water-repelling chemicals. (pp. 12-17)

January 25, 2010

Coverstory: Beyond The Basics

Laundry detergent makers and their raw material suppliers are sticking to innovation despite a rocky economy. (pp. 12-17)

Automatic Dishwasher Detergents: Phosphate Phaseout Is Opportunity For Chemical Suppliers

Web Exclusive)

January 18, 2010

Coverstory: Congressional Outlook For 2010

Climate change, chemical regulation reform will vie for Congress' attention. (pp. 10-15)

January 11, 2010

Cover Story: World Chemical Outlook

The chemical industry predicts better times in 2010. (pp. 11-19)

Markets

Construction: Recovery From Recession Will Be Long And Slow

Crop Protection: Watching Out For El Niño

Electronics: New Products Will Put Industry Back On Track

Finance: Credit Returns, But Overcapacity Casts A Shadow

Fine Chemicals: The Outlook Is Good, But The Caveats Are Several

Instrumentation: Nonindustry Users Buoy Business In Lean Times

Inorganics: Caustic Soda, Soda Ash Producers Hope For A Calmer 2010

Petrochemicals: Although Recovering, The Industry Will Soon Bear The Brunt Of New Capacity

Pharmaceuticals: Big Firms Will Fight The Patent Cliff

Specialties: 2010 Will Be All About The End Market

Regions

Asia: Economies are generally buoyant, except in Japan

Canada: Hard hit in the downturn, the country eyes recovery in 2010

Europe: Fragile recovery awaits the return of end-market demand

Latin America: Dodging the economic bullet, the region has ambitious plans

Middle East: A big chunk of ethylene capacity is coming onstream this year

United States: Chemical industry prepares for a slow recovery in 2010

Science & Technology: China Ascendant

Measured by patent applications or journal articles, growth in Chinese scientific output is stupendous. (pp. 35-37)

» Tools For Foreign Authors

January 4, 2010

Coverstory: President's Message

Being Competitive In The Global Marketplace. (pp. 2-5)

Science & Technology: Fake Pharmaceuticals

Those fighting against counterfeit medicines face increasingly sophisticated adversaries. (pp. 27-29)

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


» Latest Multimedia

» Videos

June 28, 2010

Nanostructure Dynamics

Imaging: Time-resolved electron tomography provides 3-D views on ultrafast timescale.

May 24, 2010

Dendrimersomes Debut

Supramolecular Chemistry: Self-assembled dendrimer-based structures could deliver drugs, other substances.

May 24, 2010

Dendrimersomes Debut

Supramolecular Chemistry: Self-assembled dendrimer-based structures could deliver drugs, other substances.

May 10, 2010

Lisa P. Jackson

EPA administrator is blazing trails, from regulating greenhouse gas emissions to reforming chemical management policies.

May 24, 2010

Gussman Talks Grub

Sgt. Neil Gussman demonstrates the differences between the military rations of the 1970s and today's Meals, Ready-To-Eat (MREs).

March 22, 2010

An Impasse Grows In Thailand

Political instability stops construction at chemical plants worth billions of dollars.

March 15, 2010

Stirring Liquid Metals Without A Stir Bar

Heat and a magnetic field lead liquid lithium to swirl on its own, like a whirlpool.

March 8, 2010

Carbon-Fixing Enzymes Line Up

Blue-green algae arrange carbon fixation enzyme compartments for maximum efficiency.

March 1, 2010

A World View At India's Dishman

Smart acquisitions and a knack for retaining foreign employees propel growth of drug ingredients producer.

February 8, 2010

Lights, Camera, Chemistry

Learning how to make lab demonstration videos can pay off for instructors and students.

February 8, 2010

Lights, Camera, Chemistry

Learning how to make lab demonstration videos can pay off for instructors and students.

February 5, 2010

Reaction-Driven Mixing

Fluid Dynamics: Chemical interactions drive convection and stirring.

January 15, 2010

Chemotaxis

Acidic droplet solves maze.

January 11, 2010

Templating A Molecular Donut

Nanotechnology: Molybdenum oxide cluster provides seeding ground to form donut-shaped structure.

» Photo Galleries

April 26, 2010

Gypsy Moths Keep Fluttering

ACS Meeting News: Chemical treatments to rein in invasive pest have evolved, but it's still expanding its range.

April 12, 2010

Marine Life

Photos from a trip to Little Cayman in the British West Indies.

March 22, 2010

An Impasse Grows In Thailand

Political instability stops construction at chemical plants worth billions of dollars.

October 5, 2009

Materials For Adventure

New fibers and membranes make outdoor gear lighter and more comfortable.

September 28, 2009

Getting By On Little Water

Advances in breeding and basic science confer drought tolerance to crops.

April 6, 2009

Scenes From The ACS Meeting In Salt Lake City

A photo spread and slideshow of the 237th National Meeting.

March 23, 2009

Boron Dreams

Priestley Medalist M. Frederick Hawthorne has some unfinished business

February 23, 2009

Pittcon: A Real Cover Story

February 2, 2009

Leather From Another Era

In the Hazaribagh district of Dhaka, Bangladesh, archaic tanneries put workers and the environment at ris

December 15, 2008

Having A Ball With National Chemistry Week

Through hands-on activities, demonstrations, and competitions, kids connect chemistry to sports

» Audio/Podcasts

April 26, 2010

Francis S. Collins

NIH director discusses challenges, opportunities driven by health care reform, stimulus spending, and fast pace of scientific discovery.

March 8, 2010

Skyward View

Five decades of laser technology shine light on chemistry fundamentals.

March 8, 2010

Molecular Dynamics In Real Time

Five decades of laser technology shine light on chemistry fundamentals.

March 8, 2010

Molecules At Surfaces And Interfaces

Five decades of laser technology shine light on chemistry fundamentals.

March 8, 2010

Electron Dynamics

Five decades of laser technology shine light on chemistry fundamentals.

October 5, 2009

Rebecca Kamen

A sculptor nurtures an elemental garden.

March 9, 2009

On The Bubble

Cleantech start-ups and investors weigh the odds of growing during a downturn

February 2, 2009

New Leader Takes Over At NIEHS

Toxicologist Linda Birnbaum charts course for NIH institute

November 17, 2008

Chemistry, Culture, and Camaraderie

The international chemistry olympiad offers an experience worth its weight in gold

November 17, 2008

Happy Birthday, Love Canal

It's been 30 years since the neighborhood surrounding America's most famous toxic waste dump was evacuated, yet its legacy is still unfolding

» Other Multimedia

April 27, 2009

Cellulosic Scale-Up

DOE-backed ethanol producers encounter difficulties converting waste streams to commercially viable fuel.

June 11, 2007

CAS Timeline

100 years of progress from volunteers and index cards to cutting edge computers, see the progress of CAS.

June 11, 2007

The Incredible Vastness of Data

In the hands of CAS, a morass of data points ends up telling epic research stories, page by page.

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