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December 21, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 33
COVER STORY: HYDROTHERMAL VENTS: 35
Geochemists probing the ocean subfloor find dynamic chemistry and hints of microorganisms at work.
UNUSUAL CLUSTER: 40
Hydrogenase crystal structure may aid design of industrially useful catalysts.
STUDENT JOURNAL: 41
National Journal of Young Investigators, in electronic format, gets undergraduates involved.
December 14, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 36
INTERNET SITES: 37
Some science-based web sites are labors of love.
CALIXARENES: 38
Molecular baskets are being redesigned to be receptors for specific tasks.
RESEARCH FUNDING: 41
Novartis to provide UC Berkeley with $25 million over five years.
December 7, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 39
COVER STORY: SELF-REPLICATION: 40
New experiments with peptide and nucleic acid chemistry may help to decipher molecular origins.
CARBENES AND NITRENES: 45
Character of elusive conjugated biradical intermediates is in hand at long last.
November 30, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 23
COVER STORY: BELL LABS: 24
Once a part of AT&T, technology innovator is now the R&D arm of Lucent Technologies.
OUCHLESS ADHESIVE: 29
Light-switchable bandage wins innovation award for British company.
SCIENCE INSIGHTS: 30
NIH science film festival capitalizes on teachable moments.
November 23,1998
SCIENCE/TECHNOLOGY CONCENTRATES: 37
PHOTONIC CRYSTALS: 38
Materials with arrays of large holes hold promise for development of optical-based technologies.
CHEMRAWN: 44
Conferences apply chemical research to the world's needs.
CHEMICAL SHIFTS: 46
Parameter important to NMR spectroscopy of proteins measured in solution.
November 16, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 30
HARVARD'S ICCB: 31
Institute for Chemistry & Cell Biology to provide a chemical interface between genomics, biology, and medicine.
WHAT'S THAT STUFF?: 35
Ink is a pervasive material that is essential to our everyday lives.
November 9, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 69
RIBOZYMES: 87
Two research groups independently unveil new catalytic RNA structures.
November 2, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 21
HEALING WITH LIGHT: 22
Photodynamic therapy holds promise for cancer treatment and other biomedical applications.
GENE ARCHITECTURE: 27
Cloned and characterized polyketide-antibiotic cluster may be useful in combinatorial biosynthesis.
October 26, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 36
ARTIFICIAL PHOTOSYNTHESIS: 37
Harnessing chemical systems that mimic natural processes could lead to a virtually infinite renewable supply of energy.
VANCOMYCIN: 46
Aglycon of this antibiotic is synthesized by two routes.
RESTORED VAN GOGH: 47
Restoration of dark-palette painting was aided by chemical analysis.
SCIENCE INSIGHTS: 48
Requirement to give Nobel Prize to no more than three people stirs up controversy.
October 19, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 42
NOBEL AFTERMATH: 45
Fame that comes with winning a major science prize can disrupt research as well as everyday life.
PHOTOCHEMISTRY: 47
Sunlight influences interplay of radicals and trace metals in ocean water.
October 12, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 36
DERMAL EXPOSURE: 37
Model uses data from human activity recorded on videotape to determine extent of exposure to toxics.
BIMETALLIC CATALYST: 40
Chemists have encapsulated highly dispersed nanoparticles inside the pores of a silica support.
October 5, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 41
G-QUADRUPLEXES: 42
Folded DNA structures attract growing interest as targets for therapeutic agents for treatment of cancer.
POLYPROLIFERATION: 46
Polysaccharides, polycarbonates, and polyetheresters prepared by new approaches.
September 28, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 23
COVER STORY: NMR BLOSSOMS: 25
Modeling of chemical shifts increases ability to predict the structures of even complex molecules.
SCIENCE INSIGHTS: 37
Does androstenedione give Mark McGwire extra oomph?
September 21, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 56
CHEMICAL SENSITIVITY: 57
Is it stress, imagination, or a real disease? Medical proof is elusive.
NANOMANIA: 70
Materials structures with at least one dimension smaller than 100 nm capture chemists' fancy.
NEURODEGENERATION: 78
Oxidative stress, role of NO are common characteristics of disease processes.
NUCLEIC ACID POLYMERS: 80
Designed biopolymers copied and amplified like DNA, but have chemical functionality of proteins.
September 14, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 28
COMBINATORIAL CHEMISTRY: 29
Researchers harness microorganisms to carry out combinatorial syntheses.
ANALYZING THE OCEAN: 31
Requires innovative analytical and sampling techniques.
September 7, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 30
COVER STORY: CHEMISTRY AND ART: 31
Scientists bring their expertise to bear on repair and restoration of synthetic materials.
FOOD ALLERGIES: 38
Proteins are the root of the problem for most sufferers; modifying plant genes may be a future solution.
PROCESS RESEARCH: 41
Chemists face myriad challenges to develop practical, efficient, and cost-effective large-scale syntheses.
August 31, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 23
PEPTIDE TWIST: 24
New kinds of peptide derivatives adopt defined helical folding patterns in solution.
ALLOSTERIC MODIFIERS: 25
Small-molecule drugs that bolster oxygen delivery are being developed to fight ischemic diseases.
SCIENCE INSIGHTS: 27
Who would guess that chemists can find joy in cement?
August 24, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 49
PROTEIN PROGRESS: 51
Advances in protein science were discussed at a recent symposium.
August 17, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 37
PHOSPHORUS DAZZLES: 38
International conference highlights new phosphorus-containing drugs and novel P-P half bonds.
MUNCHING ON TNT: 40
Spinach enzymes degrade explosives to potentially useful chemicals.
August 10, 1998
SCIENCE/TECHNOLOGY CONCENTRATES: 51
BREAST IMPLANTS: 53
Institute of Medicine committee charged with reviewing, clarifying safety data.
PROTEIN NMR: 55
Variation on correlation technique allows spectra of molecules 100 kilodaltons and larger in size.