Science Archives » 2011 & 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998
December 22, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CHEMISTRY HIGHLIGHTS 2003
RNA INTERFERENCE
Chemists have a pivotal role in turning RNAi into a viable therapeutic.
JACS AT 125
Karplus equation links NMR coupling constant to molecular geometry.
December 15, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
METAL ANTIAROMATICITY
Researchers debate whether metal clusters with four electrons can be called
antiaromatic.
CHEMICAL DRIVE
Student Chem-E-Car competition draws crowds at AIChE national meeting.
DIGITAL BRIEFS
December 8, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
GENOMICS & PROTEOMICS
While still proving its worth in drug R&D, genomics is providing insight into causes of disease and drug response.
PROMISCUITY'S POWER
Enzymes' ability to catalyze secondary reactions may provide a head start for evolving enzymes with new activities.
HOLD THAT MOLECULE
Researchers and teachers get their hands on accurate 3-D models made from rapid prototyping.
December 1, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
NANOTECH
K. Eric Drexler and Richard E. Smalley square off on the possibility of molecular assemblers.
SIMPLY SILICON
Chemistry at silicon surfaces adds organic function to semiconductors.
DRUG TESTING
Colorimetric test for GHB, the "date rape drug," could assist medical and law-enforcement personnel.
November 24, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
ION CHANNELS
Porphyrin molecules can bind potassium channel proteins in at least two different ways.
WHAT'S THAT STUFF?
Both fragile and ubiquitous, glass's beauty and usefulness has been clear for thousands of years.
November 17, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CATALYSIS FUNDING
Researchers seek new sources of support to remain vital as catalysis seems less in vogue.
DOPING IN SPORTS
UCLA chemists identify designer steroid THG.
JACS AT 125
In his 1936 paper, Lars Onsager showed how Debye's theory of dipoles could be extended to polar solvents.
DIGITAL BRIEFS
November 10, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
LASSO PEPTIDE
Three research groups independently report structure of a lariat-shaped antibacterial peptide.
OPEN SESAME
Middle Eastern coalition plans to open the region's first synchrotron in 2007.
November 3, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
AHA! MOMENTS
CRITTER CHEMISTRY
Australian orchid seduces pollinator wasps by producing the same pheromone.
CHEMISTRY NOBEL PRIZE
Chemistry nobelists answered basic questions about how ions and water cross cell membranes.
NOBEL HISTORY
One hundred years ago, Svante A. Arrhenius was awarded the 1903 Nobel Prize for his theory of electrolytic dissociation.
MEDICINE NOBEL CONTROVERSY
Scientist spurned by Nobel committee has both supporters and detractors.
WHAT'S THAT STUFF?
Capsaicin is responsible for the mouth-burning fire of chili peppers.
October 27, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
COMBICHEM
Evolution of field leads to advances in catalyst optimization, natural-product-like libraries, and multicomponent reactions.
FUEL DESULFURIZATION
New catalysts and processes could help industry meet EPA regulations.
DALTON BICENTENNIAL
Events in England celebrate 200th anniversary of John Dalton's atomic theory.
JACS AT 125
K. Barry Sharpless' report on converting allylic alcohols into epoxides was a Nobel Prize-winning paper.
DIGITAL BRIEFS
New software and websites for the chemical enterprise.
October 20, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
9/11 URBAN AEROSOLS
Scientists work to understand the complex mixture of dust, powder, and smoke released from ruins of the World Trade Center.
BACTERIAL BUILDERS
Microbial metabolism may be major player in geochemical processes.
October 13, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
NATURAL PRODUCTS REDUX
Drug discovery and synthetic chemistry efforts are shifting back to natural products research.
RAMAN SHAMANS
Spectroscopic method gains popularity for probing catalysts.
DESIGNER SOLVENTS
Novel reaction systems combine the best properties of homogeneous and heterogeneous catalysis.
ORGANIC SYNTHESIS
Solid-state photochemical reaction offers route to vicinal quaternary centers.
NEW PRODUCTS
New And Notable In The Chemical Industry.
October 6, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
ESTROGEN RISKS
DNA-damaging metabolites help explain hormone replacement therapy's link to breast cancer.
CHEMISTRY & BIOLOGY
Educators are urged to teach along the interface of the two fields.
DIGITAL BRIEFS
New Software And Website For The Chemical Enterprise
MEETINGS BRIEFS
September 29, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
ANALYZE THIS
Proteins and proteomics dominate the meeting of mass spec community.
GREEN FOCUS
ACS presidential event highlights green chemistry and engineering's role in finding solutions to world problems.
HELICAL ASYMMETRY
Interactions between chiral molecules of similar helicity are favored over those between molecules of opposite helicity.
LIFE SCIENCES
New institute at the University of Michigan fosters interdisciplinary collaboration.
JACS AT 125
Irving Langmuir and Katharine Blodgett brought new depth to molecule-thick films with papers published in 1918 and 1935, respectively.
September 22, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
TUNNELING CONUNDRUM
Two recent papers call enhanced enzymatic tunneling hypothesis into question
JACS MILESTONE
ACS flagship journal celebrates 125th anniversary with star-studded symposium.
ARTISTIC LICENSE
Table of elements has inspired many works of art, most recently two periodic table tables.
TRANS FATTY ACIDS
FDA will require producers to list the amount of trans fat on nutrition lables.
September 15, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
IUPAC
Congress and general assembly meet in Ottawa, reflect on chemistry's interfaces.
NEW MATERIALS AT IUPAC
Metal-containing organic materials offer numerous potential applications.
OXYPHOSPHORANE CONTROVERSY
Assignment in enzyme crystal structure is questioned.
CRITTER CHEMISTRY
The chemical signal that hornets use to locate invaders is also found in some food flavorings and fragrances.
NEW PRODUCTS
New And Notable In The Chemical Industry
September 8, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
September 1, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
SUPERPARAMAGNETIC
Researchers trap nanoscale-sized magnets within beautiful purple glass.
ELECTROCHEMICAL LOGIC
New chip combines microfluidics and electrochemistry to create logic gates.
CHEMICAL PROTEOMICS
Technique maps phosphorylation sites in proteins.
DIGITAL BRIEFS
New Software and Websites for the Chemical Enterprise
August 25, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
BEAUTIFUL CHEMISTRY
C&EN readers weigh in on chemistry's most memorable discoveries.
PROTEIN FOLDING
A large protein folds in ways that challenge theoretical predictions.
INSIGHTS
Despite the wealth of evidence against cold fusion, true believers hold out on faith.
WHAT'S THAT STUFF?
Synthetic and natural food colorings abound in grocery stores.
August 18, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
PINHOLE LEAKS
Complex chemistry lies behind pitting in copper pipes.
JACS AT 125
In 1989, Colin Bain, Ralph Nuzzo, and George Whitesides functionalized self-assembled monolayers.
August 11, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CHEMISTRY AND ART
Striking images enliven a hallway at the University of Wisconsin.
ELECTROCHEMICAL DNA DETECTOR
Reagentless and reusable analysis technique provides basis for portable analyzer.
NEW PRODUCTS
NEW AND NOTABLE IN THE CHEMICAL INDUSTRY
August 4, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
PROTEIN FOLDING
Researchers are improving their ability to predict structures of proteins.
COMPLEX FLUIDS
Rhodia's unique lab in New Jersey to study these substances is part of France's national system of academic labs.
July 28, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
ART FROM ANTIQUITY
New York's Metropolitan Museum of Art showcases Near East art from the third millennium B.C.
CATALYST RESEARCH IN MEXICO
State-run oil industry's needs for new catalysts shape research in the country's universities and national lab.
WHAT'S THAT STUFF?
Monosodium l-glutamate adds a unique boost to food flavors.
DIGITAL BRIEFS
New Software And Websites For The Chemical Enterprise.
July 14, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CHIRAL SYNTHESIS
Australian start-up company uses free-radical chemistry to produce single enantiomers.
July 7, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CANCUN CATALYSIS
Conference in Mexico draws experts from around the globe and gives locals extra exposure.
EBSCO TO THE RESCUE
Firm acquires troubled subscription agency RoweCom.
CRITTER CHEMISTRY
Researchers seek the chemical basis behind the giraffe's foul scent.
June 30, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
WHAT'S THE STINK?
Researchers investigate the chemistry behind the stench of the titan arum plant.
NEW EDUCATION FACILITY
University of San Diego's Donald P. Shiley Center for Science & Technology opens for business.
INSIGHTS
Mix -up between structural isomers reminds chemists to be diligent in ensuring accuracy.
July 21, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
R&D SPENDING GROWS
Latest NSF data show trends in academic chemical research; more tables available exclusively online.
GREEN ENGINEERING
New set of principles provides guidance to design environmentally friendlier products and processes.
GREEN ENGINEERING
New set of principles provides guidance to design environmentally friendlier products and processes.
NEW PRODUCTS
New And Notable In The Chemical Industry
June 23, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
REWORKING RNA
Chemists use nature's machinery to synthesize proteins with nonnatural amino acids.
DIGITAL BRIEFS
New Software And Websites For The Chemical Enterprise
June 16, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
JACS AT 125
Lineweaver and Burk's paper, published despite negative reviews, became the most highly cited paper to appear in JACS.
CRITTER CHEMISTRY
Polypeptide -spiral
springs may be the secret of spider silk's strength and flexibility.
June 9, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
HYDROGEN RESEARCH
Workshop focuses on issues related to developing a hydrogen-fuel economy.
ION CHANNELS
Study of voltage-dependent K+ ion channel challenges conventional model of its function.
RED ROVER
NASA's new twin rovers will seek out evidence of water on Mars.
NEW PRODUCTS
New And Notable In The Chemical Industry
June 2, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
UNDERSTANDING VIOLENCE
Brain chemistry, genetics, and environment mix to produce aggressive behavior.
BOOSTING BIOAVAILABILITY
Grapefruit compounds increase effectiveness of certain drugs prone to metabolic degradation.
May 26, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
DRUG DISCLOSURES
New drugs for HIV infection, thrombosis, cancer, and schizophrenia are introduced at ACS symposium.
CAF? AU SCIENCE
A monthly evening of cabaret connects art and science.
FILAMENTOUS VIRUSES
Polarized Raman technique yields new details on bacteriophages.
H2O2 MYSTERY
Mechanism suggests how enzymes protect cells from damage while permitting peroxide to fulfill signaling function.
INSIGHTS
Book about new theory of scent goes too far in citing persecution by scientific community.
May 19, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
NEW ZEOLITES
Researchers use common reagents to synthesize novel products.
C&EN TALKS WITH
James Trevelyan discusses the urgent problems in humanitarian demining.
JACS AT 125
George S. Hammond explained structure-reactivity relationships in organic reactions.
WHAT'S THAT STUFF?
Jell-O's primary ingredient, gelatin, gives the dessert its appeal.
DIGITAL BRIEFS
New Software And Websites For The Chemical Enterprise
May 12, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
DNA REPAIR
Research probes cellular mechanisms that fix damage done by oxidative species.
NOVEL CATALYST HUNT
Transition-state analog is used to screen a library for potential catalysts.
NEW PRODUCTS
New And Notable In The Chemical Industry.
May 5, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
LONG-TERM RESEARCH
Experts explore new paradigms for innovation.
BISPHENOL A
Controversy arises over interpretation of new findings that implicate plastics monomer in chromosomal aberrations.
NOBCChE
Conference accentuates the positive and highlights career development.
April 28, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
COMPUTATIONAL NANOTECH
Theoretical and experimental approaches are used concomitantly to design nanosystems.
NANOSAFETY
Symposium looks at how nanomaterials interact with biological systems.
WHAT'S THAT STUFF?
Soap bubbles fascinate kids of all ages.
NEVILLE REED
C&EN talks with the Royal Society of Chemistry's general manager about membership expansion.
April 21, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
A LOOK BACK IN TIME
New methods for sequencing ancient proteins may allow retrieval of valuable genetic information.
JACS AT 125
Bruce Merrifield built peptides in a stepwise fashion on a solid support, eliminating tedious purification and repeated recrystallizations.
April 14, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
TRIBOLOGY
What happens when molecules rub each other the wrong way?
POLYMER BRUSHES
Tethered polymer chains create "smart surfaces" that can adapt to their environment.
GENDER EQUITY
How women chemists overcome obstacles.
NEW PRODUCTS
New And Notable In The Chemical Industry.
April 7, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
SYNTHETIC TOOLBOX
Poster session provides milieu for displaying new reactions and reagents.
OIL CLEANUP
Symposium presents alternative measures for countering oil spill damage.
ION CHANNELS
Researchers elucidate mechanism of how cell membranes respond to osmotic pressure changes.
March 31, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
INSIGHTS
Women scientists shine at symposium honoring 1963 Nobel Laureate Maria Goeppert-Mayer.
PITTCON 2003
Features analytical chemistry's contributions to brain chemistry analysis, IR spectroscopy, chemical weapons sensing, and petroleum science.
March 24, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
PRIESTLEY MEDALIST
Industrial chemist Edwin Vandenberg is honored for his contributions to polymer science and to the chemistry community.
AAAS SPOTLIGHT
Toxicogenomics, supertasters, and the protective diets of indigenous cultures highlighted at Denver meeting.
JACS AT 125
Pauling's predictions on the metallic radii of most elements provide further detail on the complexities of bonding.
March 17, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
PROCESS CHEMISTRY
ACS conference focuses on critical issues for industrial chemists involved in drug development.
March 10, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
HUMAN BLOOD TYPES
Subtle differences in sugars on red blood cell surface are crucial for transplants and transfusions.
STABLE SEMICONDUCTOR
Pt-based organometallic has better environmental stability than virtually all known semiconducting organic polymers.
DOUBLE HELIX AT 50
Watson and Crick's discovery of DNA structure defined a biological phenomenon at the chemical level, inspiring chemists.
March 3, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CHEMICAL GENETICS
Chemists explore the biological world by synthesizing diverse arrays of small molecules.
CHEMICAL SCIENCE
Envisioning how advances in chemistry and chemical engineering will contribute to a brighter future.
FLUORINE CHEMISTRY
Conference delivers findings on nontraditional topics, including enzymes and lithography.
February 24, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
CRYSTALLIZATION
Forming proper crystals is an important aspect in drug manufacturing.
CHEMISTRY IN BRITAIN
Report finds need to spur innovation in U.K. university research.
INSIGHTS
Are plastic and duct tape a reasonable response to the terrorist threat?
February 17, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
PROTEIN DEAMIDATION
Researchers pin down this modification's physiological role as a regulatory signal.
JACS AT 125
Pearson's hard and soft acid and base concept provides qualitative basis for predicting chemical reactivity.
February 10, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
PEPTIDE-POLYMER BIOCONJUGATES
Chemists direct nanoscale synthesis with controlled living radical addition onto a solid peptide support.
GIULIO NATTA'S CENTENNIAL
A look at the life of the 1963 Chemistry Nobel Laureate, a pioneer in the field of stereoregular polymers.
WHAT'S THAT STUFF?
Chemistry gives a brighter smile through teeth whiteners.
February 3, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
ENZYME INHIBITOR
Drug design combines theoretical and empirical methods to mimic enzyme's transition-state structure.
January 27, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
SNOOZE NEWS
Insights into the chemical regulation of sleep and new drugs for narcolepsy and insomnia nudge the field.
THIOGLYCOLIGASES
Technique for enzymatic synthesis of sulfur-linked oligosaccharides will be useful for constructing thioglycosylated proteins.
WHAT'S THAT STUFF?
Opal's play of color comes from parallel planes of quartz interspersed with water.
JACS AT 125
Woodward and Hoffmann paper in 1965 set rules for predicting stereochemistry of electrocyclic reactions.
January 20, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
ALTERNATIVE ENERGY
Fuel-cell prototypes for a host of applications are generally robust, but it will be a while before products are widely marketed.
UNDERWATER TREASURE
Recently discovered marine bacteria may lead to new classes of antibiotic and anticancer drugs.
NEW PRODUCTS
New And Notable In The Chemical Industry
January 13, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
BIOMOLECULE PROBE
Raman optical activity spectroscopy gains importance for investigating solution structure and behavior of biomolecules.
DRUG HUNTING
Anti-idiotypic imprinting and direct molding shape novel bioactive compounds from polymeric cavities and enzyme active sites, respectively.
DIGITAL BRIEFS
New Software And Websites For The Chemical Enterprise
January 6, 2003
SCIENCE/TECHNOLOGY CONCENTRATES
FLEXIBLE ELECTRONICS
Symposium on incorporating electronics into materials such as fabric and plastic highlights advances and challenges.
DYES PERFORM LOGIC FUNCTIONS
Ion indicators illuminated by various wavelengths of light make up a wet molecular logic system.