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December 18, 2006
Science & Technology Concentrates
Academic R&D Spending Trends
Chemical research sector grew 7.3% in 2004, slightly less than the average for science as a whole.
Golden Chemical Engineering Days
Annual AIChE meeting draws chemical engineers to San Francisco for science and camaraderie.
Meetings Briefs
Presentations made during the American Institute of Chemical Engineers annual meeting, held on Nov. 12?17 in San Francisco.
Clarions For Sustainability
Chemical engineers call for action and offer ways to meet future energy and natural resource needs.
December 11, 2006
Science & Technology Concentrates
Chemical Biology of the Cell
Symposium probed chemistry of nucleus, cytoplasm, cell division, metals, metabolites, membranes.
Inside Instrumentation
Technology and Business news for the laboratory world.
New Products
New And Notable In The Chemical Industry.
December 4, 2006
Science & Technology Concentrates
Scripps Takes A New Approach
Florida campus brings drug discovery to the academic arena.
Luminous With Promise
Geologists applaud an intelligent decision about intelligent design.
Weighing Reproducibility
Researchers confront an array of issues and questions when experimental work cannot be reproduced.
Living Organisms Join The Jet Set
London biophysicist is developing jet-based technologies to encapsulate living cells.
Fungi To The Rescue
Biopesticide derived from mold has promise as a greener method for eradicating insect pests.
Jamie Ginn
Miss America contestant representing Delaware is a chemical engineer, actor, and dancer.
November 27, 2006
Science & Technology Concentrates
Globalization Of Science Rolls On
Visible even from space, the conspicuous chemistry of bioluminescence continues to open new research and technology niches.
Judging Science
Geologists applaud an intelligent decision about intelligent design.
November 20, 2006
Science & Technology Concentrates
Walking The Line
Protein motors march cargo to the extremities of a cell and drag apart DNA during mitosis.
Complexity To Live By
This year's Nobel Prize In Chemistry highlights the elegant complexity biology musters to read genes.
Largest Synthetic Hetero-Oligosaccharide
Milestone could lead to better understanding of major bacterial diseases.
Perspective
Looming Threats To Society Journals.
Digital Briefs
New Software and Websites for the Chemical Enterprise.
November 13, 2006
Science & Technology Concentrates
A China-California Connection
French chemist carries out phosphorus research with one foot in the U.S. and the other in China.
Cover Story: RNA Interference
Industrial, academic researchers develop synthetic delivery systems for RNAi therapeutics and advance candidates toward the clinic.
Meeting Briefs
Inside Instrumentation
Technology and Business news for the laboratory world.
November 6, 2006
Science & Technology Concentrates
Making The Cover
Scientific art on journal covers raises visibility, but does it still serve a purpose in the Internet age?
Thomas E. Graedel
Industrial ecologist's work prompts scientists to plan ahead for possible limits on natural resources.
October 30, 2006
Science & Technology Concentrates
Polymers With Safe Amounts Of Copper
New polymerization techniques that reduce catalyst contamination of products could find broad industrial use.
What's That Stuff? Citronella Oil
New Software and Websites for the Chemical Enterprise.
A Dark Matter For Chemists
Powerful new evidence for existence of dark matter in the cosmos prompts speculation about its 'chemical' properties.
October 23, 2006
Science & Technology Concentrates
Chemistry For The Sake Of Art
For one Long Island artist, her studio is her laboratory.
Digital Briefs
New Software and Websites for the Chemical Enterprise.
Cover Story: Bacterial Conversations
Using a chemical language, bacteria coordinate everything from infection to plaque buildup.
Battling Biofilms
It took decades before researchers believed that bacteria were sophisticated enough to organize into slimy biofilms.
Talking To The Hosts
Bacteria find ways to have chemical conversations with their hosts as well.
October 16, 2006
Science & Technology Concentrates
Chemistry Tour De Force In Hungary
Budapest congress provides European forum for the key challenges at the frontiers of chemistry today.
Meetings Briefs
Presentations made during the 1st European Chemistry Congress, held on Aug. 27-31, in Budapest.
Five Decades Of Marcus Theories
Symposium celebrates golden anniversaryof seminal electron-transfer and reaction-rate theories.
San Francisco Surface Science
Potpourri of surface studies rangesfrom model systems to complex reactions.
New Products
New and notable in the chemical industry.
October 9, 2006

Cover Story: Richard E. Smalley
C&EN marks the 10th anniversary of the fullerene scientist's Nobel Prize and the first anniversary of the loss of this civic-minded nanotechnology pioneer.
Science & Technology Concentrates

Targeting Telomerase
Researchers believe enzyme could be a nearly universal target for anticancer drugs.
Environmental Nervous System
Rigging the world with chemical sensors is a technical challenge with big potential payoffs.
Inside Instrumentation
Technology and business news for the laboratory world.
October 2, 2006
Science & Technology Concentrates

Cover Story: Mass Spec Tackles Proteins
Mass spectrometry shines in applications from proteomics to structural biology, but challenges remain.
Measuring Natural Disasters' Punch
Scientists cite baseline environmental data as key to assessing hurricanes' impact.

Neuron Activation
Scientists crack how a family of brain cell receptors receives and responds to chemical signals.
September 25, 2006

Cover Story: Drugs To Fight Addictions
A better understanding of the mechanisms of drug and alcohol dependence is helping to further development and use of pharmacotherapies against addictions.
September 25, 2006
Science & Technology Concentrates

ACS Meeting Potpourri
Diverse research presented includes molecular knots and musical chemical reactions.
Farm Emissions Control
Research aims to characterize and control odors and VOC emissions from livestock.
Planning For Nuclear Energy R&D
DOE workshop draws nuclear scientists and engineers to identify key research needs.

Much Ado About Pluto
The former ninth planet's demotion has angered some, but it puts chemists in a good light.
September 18, 2006
Science & Technology Concentrates
September 18, 2006

Protein Control And Modification
At 20th Protein Society symposium, researchers show how to poke, perturb, and redesign proteins.
September 18, 2006
Digital Briefs
New software and websites for the chemical enterprise.
September 11, 2006
Science & Technology Concentrates

Incredible Colors
Scientific investigations unmask the secrets of 16th-century Venetian painters' palettes.
Inside Instrumentation
Technology and business news for the laboratory world.
September 4, 2006
Cover Story: Glycosylation Engineering
Controlling personalities tame wild sugars on proteins and natural products.
Science & Technology Concentrates
Road To Recovery
A year after the hurricanes, scientists and industry workers reflect on the impact on their work and lives.
September 4, 2006

Squint Busters
Tool builders are pushing optical microscope vision to single-molecule sharpness.
Meeting Briefs
Roundup from the American Society of Plant Biologists and the Canadian Society of Plant Physiologists joint annual conference on Aug. 5-9 in Boston.
August 28, 2006
Science & Technology Concentrates

Putting A Spin On Electronics
Potential for advanced technologies drives search for room-temperature magnetic semiconductors.
Chemistry Innovation Network Is Set Up In U.K.
Knowledge-transfer organization aims to benefit British chemistry-using industries.
Anniversary Of RNA Double-Helix Discovery
Structure was created in the lab by carrying out the first nucleic acid hybridization reaction.
The Dope On Testosterone Tests
Sound drug-testing procedures provide facts but don't determine the fate of athletes caught cheating.
New Products
New and notable in the chemical industry.
August 21, 2006
Science & Technology Concentrates
A Periodic Table Of Nanoparticles
Like chemical elements, nanoparticles of distinct types combine in definite proportions.
Biorefinery Gets Ready To Deliver The Goods
Italian levulinic acid facility is first to make targeted biomass-based chemical feedstocks.
Sulfation Code Found
Once thought to be simply tissue matrix, chondroitin sulfate is now shown to encode function.
What's That Stuff? Chicken Eggs
So ordinary yet so versatile, eggs are a complex scramble of chemical compounds.
August 14, 2006
Science & Technology Concentrates
Cover Story: Fine Chemicals & Pharmaceuticals
Producers are taking advantage of enzymes to prepare single-enantiomer compounds.
Online Archives On A Bumpy Road
Digital repositories have garnered mixed reviews?everything from enthusiasm to apathy.
Twist and Stretch
When small stretching forces are applied, DNA winds up more tightly rather than lengthening.
Reading The Neanderthal Code
German-U.S. collaborative effort embarks on project to sequence the Neanderthal genome.

Crucible Secrets
Archaeologists examine early labware in search of clues as to why they worked so well.
Inside Instrumentation
Technology and business news for the laboratory world.
August 7, 2006
Science & Technology Concentrates
Cover story: Battling Breast Cancer
By targeting multiple HER-family receptors, small-molecule drugs could fill the therapeutic gaps left by Herceptin.
A Boost For Biosensors
Beefing up signal of FRET kinase biosensors makes inexpensive high-throughput screening possible.
Digital Briefs
New software and websites for the chemical enterprise.
July 31, 2006
Cover Story: Systems Biology's Clinical Future
Although it now remains a research tool, systems biology is moving toward clinical applications, including personalized medicine.
Science & Technology Concentrates

Quadruplex In Its Element
Structures of human telomeric quadruplex in cell-like solution have implications for anticancer therapeutics.
Preston MacDougall
Chemistry professor weaves together science and society on his weekly radio gig.

July 24, 2006
Science & Technology Concentrates
Open-Source Science
Online research communities aim to unite scientists worldwide to find cures for neglected diseases.
Meetings Briefs
Presentations made during the 10th Green Chemistry & Engineering Conference, held June 26-30 in Washington, D.C.
July 17, 2006
Science & Technology Concentrates
Cover Story: Epigenetics
Chemical signposts on the genome's chromatin landscape turn genes on and off.
Still Blazing Trails At 75
Gordon Research Conferences celebrate a rich history of nurturing the frontiers of science.

Raven Hanna
A molecular biophysicist gives up the lab bench to follow another molecular muse.
July 10, 2006
Science & Technology Concentrates
Going Green Keeps Getting Easier
Presidential honors reward advances in chemistry that promote pollution prevention and sustainability.
ACHEMA Takes A Look At Nanomaterials
Symposium, exhibition spotlight developments in nanoparticle production technology.

Whipping Up Metal Foams
Combustion synthesis yields unprecedented nanoporous transition-metal materials.
Inside Instrumentation
Technology and Business News for the Laboratory World
Juy 3, 2006
Science & Technology Concentrates
Juy 3, 2006

Mood Of Optimism Reigns At ACHEMA
Frankfurt chemical process industries trade fair attracts increased number of exhibitors.
ACHEMA 2006 Highlights Analysis, Automation
Frankfurt trade fair features wide range of instrumentation for process industries.
Minimizing Drug Toxicity
Conference spotlights advances in mechanistic studies and in methods to predict toxicity.
Piercing The Veil Of Creativity
Conference shows that teachable tools, not just serendipity, can stimulate innovation.
Digital Briefs
New Software and Websites for the Chemical Enterprise.
June 26, 2006
Science & Technology Concentrates
Daly's Adventure
NIH scientist has trekked the world to chronicle nature's own chemistry but now faces toughest road.

Catalyst In A Cage
Researchers improve oxidation catalysis by incorporating ligands into metal-organic framework.
AIChE Recovers Its Footing
After years of net deficits, chemical engineering society announces 'dramatic financial turnaround'.
C&EN Talks With Rachel Morgan Theall
Postdoctoral fellow's passion is trying to get high school students interested in science.
New Products
New and notable in the chemical industry.
June 19, 2006
Science & Technology Concentrates

Special Issue
Pharma's Road Ahead
C&EN examines how the pharmaceutical industry, now on the defensive, is trying to win back the public's confidence and enhance productivity.
June 12, 2006
Science & Technology Concentrates

Lithium Batteries With More Muscle
Innovations in battery materials are leading to applications heftier than portable electronics.
Raincoats
Charles Macintosh's waterproof-fabric concept, patented more than 180 years ago, is still relevant.
Inside Instrumentation
Technology and Business News for the Laboratory World.

June 5, 2006
Fabulous Fluorine
Having fluorine in life sciences molecules brings desirable benefits, but the trick is getting it in place and making sought-after building blocks.
Constructing Life Sciences Compounds
Fluorinated building blocks are increasingly used as the basis of valuable active molecules.
Science & Technology Concentrates

Making Fuels Synthetically
Fundamental advances in Fischer-Tropsch chemistry may boost method's efficiency and popularity.
Quinone Ligand Ups Ante For Rhodium
Novel complexes expand role of premier catalyst metal, including applications in materials science.

In Pursuit of Synthetic EPO
Complex erythropoietin-like glycopeptides are made from scratch.
May 29, 2006

Science & Technology Concentrates
Fixing Phosphorus
Niobium complex allows MIT chemists to build compounds from elemental phosphorus.
The Power Of Procrastination
Caltech instructor and his comic strip champion a rethinking of the merits of putting things off.
Digital Briefs
New Software and Websites for the Chemical Enterprise.
May 22, 2006
Science & Technology Concentrates
Halogenases
Scientists are learning the structural and mechanistic secrets of the exquisitely selective enzymes that nature uses to install halogen atoms.

Analytica Meets For 20th Time
Attendance drops at biennial instrumentation trade show but still exceeds organizers' expectations.
Sugars Attach Nanotubes to Cells
Carbohydrate-coated carbon nanotubes mimic cell surfaces and interface with cells.

Imaging Spin Noise
New technique is analogous to magnetic resonance imaging, but without the radio pulses.
May 15, 2006
Science & Technology Concentrates
Archives For Africa
Royal Society of Chemistry offers free online access to its scientific journal archive.

Metallography
Striking photographs reveal metallic microscapes beautiful enough to hang in an art gallery.
May 8, 2006
Science & Technology Concentrates

Two-Body Solution
How dual-chemist couples found happiness, job satisfaction, and work/life balance.
Building On Success
Meeting of black chemists and chemical engineers highlights science, professional growth.

A Sweet Start For Inhalable Insulin
New approach to delivering insulin scores a first for both diabetes and pulmonary drug delivery.
Inside Instrumentation
Technology and Business News for the Laboratory World.
New Products
New and notable in the chemical industry.
May 1, 2006
Science & Technology Concentrates

Vintage Chemistry
The color changes that occur as wine ages are due to complex chemistry involving many compounds.
Big Molecules In Space
Prebiotic molecules in interstellar space are hard to detect and study, but astrochemists are closing in.
Digital Briefs
New Software and Websites for the Chemical Enterprise.
April 24, 2006
Science & Technology Concentrates

Digging Deeply Into The Past
Chemistry is increasingly helping archaeologists answer questions of what, where, and when.
Exploiting Polymer Nanostructures
Nanoscale control of polymer systems has been shown to influence macroscopic properties.
In Praise Of The Nose
Fragrance designer Michael Papas philosophizes about perfumes and reveals what goes into them.
From Manuscript To Journal Publication
Much of the process is automated, but technical editors still read every word of the manuscript.
April 17, 2006
Science & Technology Concentrates

Physicists Cast Anchor In Baltimore
Meeting spotlights novel electronic materials, antibiotic coatings, and an antiaging skin cream.
Planning Nanotech From The Ground Up
Scientists aim to design and produce safe, high-performance nanomaterials 'right the first time'.
Making Troubled Waters Potable
An inexpensive water treatment technology is making a difference in poor communities around the world.

What's That Stuff? Marshmallow
Gelatin has largely replaced the spongy confection's namesake, a plant-root ingredient.
New Products
New And Notable In The Chemical Industry.
April 10, 2006
Science & Technology Concentrates

Picking Apart Parkinson's
Researchers are seeking earlier detection and method to slow progression of disabling disease.
Journals Grapple With Ethics Issues
Scientific fraud and other serious ethical violations pose persistent questions, challenges for editors.

Deep-Sea Harvest
Marine microorganisms yield an abundance of new natural products with therapeutic potential.
A Taste Of Chemistry
Meeting highlights include ultrahydrophobic films, peptide antibiotics, gas chromatography detection.
Inside Instrumentation
Technology And Business News For The Laboratory World.
April 3, 2006
Science & Technology Concentrates

All That Glows
Bioluminescence provides practical applications while still remaining a mystery.
What's That Stuff? Beer
Brewing beer from cereals relies on a variety of biological, chemical, and physical processes.
Digital Briefs
New Software and Websites for the Chemical Enterprise.
March 27, 2006
Science & Technology Concentrates

Shedding Light On DNA Replication
Mechanistic studies fill holes in understanding of various aspects of DNA replication.
Storing Hydrogen In Polymer Pores
Polymers that inefficiently pack space adsorb significant quantities of hydrogen at 77 K.

Fullerene For The Face
Cosmetics containing C60 nanoparticles are entering the market, even if their safety is unclear.
March 20, 2006
Science & Technology Concentrates
Sprites Trigger Sky-High Chemistry
High-altitude lightning is visually stunning, but is it also a player in atmospheric chemistry?.

Molecules As Fossils
Mass spectrometry is helping paleontologists dig up molecular clues about prehistoric creatures.
Academic Chemistry After Katrina
Chemistry departments at New Orleans universities suffer less than some, but difficulties remain.
New Products
New and Notable in the Chemical Industry.
Science In India
Aided by the return of expatriates and ample money for R&D, India is building its drug discovery capabilities, fostering interdisciplinary science, and developing a vibrant postdoc culture.
Building R&D For Drug Discovery
Seasoned expatriates trickle back to help Indian pharmaceutical firms push into discovery research
Collaboration
Indian Pharma Bets On Links With Academia And Government
Bridges Wait To Be Built
India struggles to foster interdisciplinary science
Keeping Postdocs At Home In India
A vibrant postdoc culture could invigorate India's research climate, but recruiting remains difficult
A World Apart
Divergence of undergrad education and scientific research in India has been detrimental to both
A Funding Evolution
Some of India's scientists find research dollars easier than ever to obtain, but inequities remain
March 13, 2006
Science & Technology Concentrates
Supersize Enzymes Come Into Focus
Architectures of fungal and mammalian fatty acid synthases are determined at 5-? resolution.

Nanoparticles Form Diamond-like Crystals
Electrostatic interactions bring together oppositely charged nanoparticles in an unexpected way.
Enzyme Rescued for first time In Live Cells
Small molecules is used to partially restore lost activity of a disabled enzyme.

What's That Stuff? Motor Oil
Lubricant keeps car engines from clanging apart, sparks debates on how often it should be changed.
Inside Instrumentation
Technology and Business News for the Laboratory World.
March 6, 2006
Science & Technology Concentrates

Explaining C-H Bond Strengths
Alternative to hyperconjugation invokes steric strain, but not everyone is buying the idea.
Digital Briefs
New Software and Websites for the Chemical Enterprise
February 27, 2006
Science & Technology Concentrates
A Magnet For Talent
Singapore prepares to move up the R&D value chain by building a research infrastructure with both foreign and homegrown talent.
An Unlikely Center For Pharmaceuticals
India has skilled labor and China has raw materials, but big drug companies prefer Singapore.
Educational Alliance Takes Next Step
Singaporean universities and MIT launch second phase of their education and research partnership.
Sowing The Seeds Of Oriented Films
Technique allows systematic manipulation of pore orientation in molecular sieve thin films.
Trip Of A Century
Albert Hofmann, inventor of the mind-altering drug LSD, celebrates his 100th birthday

C&EN Talks With Haldor Tops?e
Veteran Danish catalysis developer's focus remains rooted in fundamental science.
February 20, 2006
Science & Technology Concentrates

Wiring Electronics With Nanotubes
Nanoscale carbon wire offers advantages as an electronic material in displays, flexible electronics.
New Journal Offers Open Peer Review
Biology Direct joins a small band of online journals that make their referees' reviews public.
Electrochemistry
Researchers are using electrochemical techniques to observe the chemistry of neurons in the human brain.
February 13, 2006
Science & Technology Concentrates

The Great Unplugging
Hunger for mobility energizes the battery business, drives efforts to develop longer lasting batteries.
Lithium-Ion Batteries
The Marketplace Beckons For More Innovation.
Naked-Eye Sensors Detect Anions
Thiourea-based colorimetric sensors recognize biologically important anions in aqueous solution.
Research Lab Disbanded
Dye derived from green henna leaves is used to decorate the body with intricate designs.
Radicals Tell Mice What's Up and Down
Reactive oxygen species are found to play a role in helping mice develop a sense of balance.
Inside Instrumentation
Technology and Business News for the Laboratory World.
February 6, 2006
Science & Technology Concentrates

The Secret Life Of Plant Crystals
Microscopic view of plant tissue reveals a hidden world of calcium oxalate crystals of diverse shapes.
What's That Stuff? Henna
Dye derived from green henna leaves is used to decorate the body with intricate designs.
January 30, 2006
Science & Technology Concentrates
Crystal Ball On The Environment
Detective work and expertise are used to evaluate environmental contaminants of emerging concern.

Shifting Sensibilities In Molecular Sensors
Molecular recognition arrays offer an alternative to lock-and-key approach.
What's Next In The Evolution Debate?
Dover ruling is a setback for intelligent design, but antievolutionists are pursuing other tactics.
Digital Briefs
New software and websites for the chemical enterprise.
January 23, 2006
Science & Technology Concentrates

Gentler X-Ray Spectroscopy
Symposium focuses on analytical applications of absorption and emission methods.
Seeking Chemical Clues To Earthquakes
Scientists are drilling miles into Earth to probe the chemistry and mechanics of the San Andreas Fault.
New Products
New And Notable In The Chemical Industry.
January 16, 2006
Science & Technology Concentrates

Bar Coding Life
A global project to create a new framework for identifying all biological species gains momentum.
Glassblowing
Trade may be in decline because of changing technologies and medical advances, but glassblowers still play a pivotal role.
January 9, 2006
Science & Technology Concentrates
Blocking Genome Gatekeepers
Scientists pin hopes on histone deacetylase inhibitors for cancer therapy, biological studies.
Ketenes Turn 100
Chemists gather to celebrate centennial of synthetically useful family of compounds.
Inside Instrumentation
Technology and Business News for the Laboratory World.

Polyurethane Foam
From furniture cushions to insulation, versatile polymer has found a world of applications.
January 2, 2006
Science & Technology Concentrates
Pacifichem Potpourri
Meeting highlights include magnetic wastewater treatment, potential peptide drugs, silole chemistry.
Cracking The Concrete Ceiling
Japanese government gets behind efforts to increase the number of women scientists in the country.

Salvaging NASA's Crashed Genesis Mission
After a year of cleaning up fragments of the solar-wind collectors, scientists are getting results.