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Science & Technology

December 18, 2006

Science & Technology Concentrates

Academic R&D Spending Trends

Chemical research sector grew 7.3% in 2004, slightly less than the average for science as a whole.

Golden Chemical Engineering Days

Annual AIChE meeting draws chemical engineers to San Francisco for science and camaraderie.

Meetings Briefs

Presentations made during the American Institute of Chemical Engineers annual meeting, held on Nov. 12?17 in San Francisco.

Clarions For Sustainability

Chemical engineers call for action and offer ways to meet future energy and natural resource needs.

December 11, 2006

Science & Technology Concentrates

Chemical Biology of the Cell

Symposium probed chemistry of nucleus, cytoplasm, cell division, metals, metabolites, membranes.

Inside Instrumentation

Technology and Business news for the laboratory world.

New Products

New And Notable In The Chemical Industry.

December 4, 2006

Science & Technology Concentrates

Scripps Takes A New Approach

Florida campus brings drug discovery to the academic arena.

Luminous With Promise

Geologists applaud an intelligent decision about intelligent design.

Weighing Reproducibility

Researchers confront an array of issues and questions when experimental work cannot be reproduced.

Living Organisms Join The Jet Set

London biophysicist is developing jet-based technologies to encapsulate living cells.

Fungi To The Rescue

Biopesticide derived from mold has promise as a greener method for eradicating insect pests.

Jamie Ginn

Miss America contestant representing Delaware is a chemical engineer, actor, and dancer.

November 27, 2006

Science & Technology Concentrates

Globalization Of Science Rolls On

Visible even from space, the conspicuous chemistry of bioluminescence continues to open new research and technology niches.

Judging Science

Geologists applaud an intelligent decision about intelligent design.

November 20, 2006

Science & Technology Concentrates

Walking The Line

Protein motors march cargo to the extremities of a cell and drag apart DNA during mitosis.

Complexity To Live By

This year's Nobel Prize In Chemistry highlights the elegant complexity biology musters to read genes.

Largest Synthetic Hetero-Oligosaccharide

Milestone could lead to better understanding of major bacterial diseases.

Perspective

Looming Threats To Society Journals.

Digital Briefs

New Software and Websites for the Chemical Enterprise.

November 13, 2006

Science & Technology Concentrates

A China-California Connection

French chemist carries out phosphorus research with one foot in the U.S. and the other in China.

Cover Story: RNA Interference

Industrial, academic researchers develop synthetic delivery systems for RNAi therapeutics and advance candidates toward the clinic.

Meeting Briefs

Inside Instrumentation

Technology and Business news for the laboratory world.

November 6, 2006

Science & Technology Concentrates

Making The Cover

Scientific art on journal covers raises visibility, but does it still serve a purpose in the Internet age?

Thomas E. Graedel

Industrial ecologist's work prompts scientists to plan ahead for possible limits on natural resources.

October 30, 2006

Science & Technology Concentrates

Polymers With Safe Amounts Of Copper

New polymerization techniques that reduce catalyst contamination of products could find broad industrial use.

What's That Stuff? Citronella Oil

New Software and Websites for the Chemical Enterprise.

A Dark Matter For Chemists

Powerful new evidence for existence of dark matter in the cosmos prompts speculation about its 'chemical' properties.

October 23, 2006

Science & Technology Concentrates

Chemistry For The Sake Of Art

For one Long Island artist, her studio is her laboratory.

Digital Briefs

New Software and Websites for the Chemical Enterprise.

Cover Story: Bacterial Conversations

Using a chemical language, bacteria coordinate everything from infection to plaque buildup.

Battling Biofilms

It took decades before researchers believed that bacteria were sophisticated enough to organize into slimy biofilms.

Talking To The Hosts

Bacteria find ways to have chemical conversations with their hosts as well.

October 16, 2006

Science & Technology Concentrates

Chemistry Tour De Force In Hungary

Budapest congress provides European forum for the key challenges at the frontiers of chemistry today.

Meetings Briefs

Presentations made during the 1st European Chemistry Congress, held on Aug. 27-31, in Budapest.

Five Decades Of Marcus Theories

Symposium celebrates golden anniversaryof seminal electron-transfer and reaction-rate theories.

San Francisco Surface Science

Potpourri of surface studies rangesfrom model systems to complex reactions.

New Products

New and notable in the chemical industry.

October 9, 2006

Cover Story: Richard E. Smalley

C&EN marks the 10th anniversary of the fullerene scientist's Nobel Prize and the first anniversary of the loss of this civic-minded nanotechnology pioneer.

Science & Technology Concentrates

Targeting Telomerase

Researchers believe enzyme could be a nearly universal target for anticancer drugs.

Environmental Nervous System

Rigging the world with chemical sensors is a technical challenge with big potential payoffs.

Inside Instrumentation

Technology and business news for the laboratory world.

October 2, 2006

Science & Technology Concentrates

Cover Story: Mass Spec Tackles Proteins

Mass spectrometry shines in applications from proteomics to structural biology, but challenges remain.

Measuring Natural Disasters' Punch

Scientists cite baseline environmental data as key to assessing hurricanes' impact.

Neuron Activation

Scientists crack how a family of brain cell receptors receives and responds to chemical signals.

September 25, 2006

Cover Story: Drugs To Fight Addictions

A better understanding of the mechanisms of drug and alcohol dependence is helping to further development and use of pharmacotherapies against addictions.

September 25, 2006

Science & Technology Concentrates

ACS Meeting Potpourri

Diverse research presented includes molecular knots and musical chemical reactions.

Farm Emissions Control

Research aims to characterize and control odors and VOC emissions from livestock.

Planning For Nuclear Energy R&D

DOE workshop draws nuclear scientists and engineers to identify key research needs.

Much Ado About Pluto

The former ninth planet's demotion has angered some, but it puts chemists in a good light.

September 18, 2006

Science & Technology Concentrates

September 18, 2006

Protein Control And Modification

At 20th Protein Society symposium, researchers show how to poke, perturb, and redesign proteins.

September 18, 2006

Digital Briefs

New software and websites for the chemical enterprise.

September 11, 2006

Science & Technology Concentrates

Incredible Colors

Scientific investigations unmask the secrets of 16th-century Venetian painters' palettes.

Inside Instrumentation

Technology and business news for the laboratory world.

September 4, 2006

Cover Story: Glycosylation Engineering

Controlling personalities tame wild sugars on proteins and natural products.

Science & Technology Concentrates

Road To Recovery

A year after the hurricanes, scientists and industry workers reflect on the impact on their work and lives.

September 4, 2006

Squint Busters

Tool builders are pushing optical microscope vision to single-molecule sharpness.

Meeting Briefs

Roundup from the American Society of Plant Biologists and the Canadian Society of Plant Physiologists joint annual conference on Aug. 5-9 in Boston.

August 28, 2006

Science & Technology Concentrates

Putting A Spin On Electronics

Potential for advanced technologies drives search for room-temperature magnetic semiconductors.

Chemistry Innovation Network Is Set Up In U.K.

Knowledge-transfer organization aims to benefit British chemistry-using industries.

Anniversary Of RNA Double-Helix Discovery

Structure was created in the lab by carrying out the first nucleic acid hybridization reaction.

The Dope On Testosterone Tests

Sound drug-testing procedures provide facts but don't determine the fate of athletes caught cheating.

New Products

New and notable in the chemical industry.

August 21, 2006

Science & Technology Concentrates

A Periodic Table Of Nanoparticles

Like chemical elements, nanoparticles of distinct types combine in definite proportions.

Biorefinery Gets Ready To Deliver The Goods

Italian levulinic acid facility is first to make targeted biomass-based chemical feedstocks.

Sulfation Code Found

Once thought to be simply tissue matrix, chondroitin sulfate is now shown to encode function.

What's That Stuff? Chicken Eggs

So ordinary yet so versatile, eggs are a complex scramble of chemical compounds.

August 14, 2006

Science & Technology Concentrates

Cover Story: Fine Chemicals & Pharmaceuticals

Producers are taking advantage of enzymes to prepare single-enantiomer compounds.

Online Archives On A Bumpy Road

Digital repositories have garnered mixed reviews?everything from enthusiasm to apathy.

Twist and Stretch

When small stretching forces are applied, DNA winds up more tightly rather than lengthening.

Reading The Neanderthal Code

German-U.S. collaborative effort embarks on project to sequence the Neanderthal genome.

Crucible Secrets

Archaeologists examine early labware in search of clues as to why they worked so well.

Inside Instrumentation

Technology and business news for the laboratory world.

August 7, 2006

Science & Technology Concentrates

Cover story: Battling Breast Cancer

By targeting multiple HER-family receptors, small-molecule drugs could fill the therapeutic gaps left by Herceptin.

A Boost For Biosensors

Beefing up signal of FRET kinase biosensors makes inexpensive high-throughput screening possible.

Digital Briefs

New software and websites for the chemical enterprise.

July 31, 2006

Cover Story: Systems Biology's Clinical Future

Although it now remains a research tool, systems biology is moving toward clinical applications, including personalized medicine.

Science & Technology Concentrates

Quadruplex In Its Element

Structures of human telomeric quadruplex in cell-like solution have implications for anticancer therapeutics.

Preston MacDougall

Chemistry professor weaves together science and society on his weekly radio gig.

July 24, 2006

Science & Technology Concentrates

Open-Source Science

Online research communities aim to unite scientists worldwide to find cures for neglected diseases.

Meetings Briefs

Presentations made during the 10th Green Chemistry & Engineering Conference, held June 26-30 in Washington, D.C.

July 17, 2006

Science & Technology Concentrates

Cover Story: Epigenetics

Chemical signposts on the genome's chromatin landscape turn genes on and off.

Still Blazing Trails At 75

Gordon Research Conferences celebrate a rich history of nurturing the frontiers of science.

Raven Hanna

A molecular biophysicist gives up the lab bench to follow another molecular muse.

July 10, 2006

Science & Technology Concentrates

Going Green Keeps Getting Easier

Presidential honors reward advances in chemistry that promote pollution prevention and sustainability.

ACHEMA Takes A Look At Nanomaterials

Symposium, exhibition spotlight developments in nanoparticle production technology.

Whipping Up Metal Foams

Combustion synthesis yields unprecedented nanoporous transition-metal materials.

Inside Instrumentation

Technology and Business News for the Laboratory World

Juy 3, 2006

Science & Technology Concentrates

Juy 3, 2006

Mood Of Optimism Reigns At ACHEMA

Frankfurt chemical process industries trade fair attracts increased number of exhibitors.

ACHEMA 2006 Highlights Analysis, Automation

Frankfurt trade fair features wide range of instrumentation for process industries.

Minimizing Drug Toxicity

Conference spotlights advances in mechanistic studies and in methods to predict toxicity.

Piercing The Veil Of Creativity

Conference shows that teachable tools, not just serendipity, can stimulate innovation.

Digital Briefs

New Software and Websites for the Chemical Enterprise.

June 26, 2006

Science & Technology Concentrates

Daly's Adventure

NIH scientist has trekked the world to chronicle nature's own chemistry but now faces toughest road.

Catalyst In A Cage

Researchers improve oxidation catalysis by incorporating ligands into metal-organic framework.

AIChE Recovers Its Footing

After years of net deficits, chemical engineering society announces 'dramatic financial turnaround'.

C&EN Talks With Rachel Morgan Theall

Postdoctoral fellow's passion is trying to get high school students interested in science.

New Products

New and notable in the chemical industry.

June 19, 2006

Science & Technology Concentrates

cover image

Special Issue

Pharma's Road Ahead

C&EN examines how the pharmaceutical industry, now on the defensive, is trying to win back the public's confidence and enhance productivity.

June 12, 2006

Science & Technology Concentrates

Lithium Batteries With More Muscle

Innovations in battery materials are leading to applications heftier than portable electronics.

Raincoats

Charles Macintosh's waterproof-fabric concept, patented more than 180 years ago, is still relevant.

Inside Instrumentation

Technology and Business News for the Laboratory World.

June 5, 2006

Fabulous Fluorine

Having fluorine in life sciences molecules brings desirable benefits, but the trick is getting it in place and making sought-after building blocks.

Constructing Life Sciences Compounds

Fluorinated building blocks are increasingly used as the basis of valuable active molecules.

Science & Technology Concentrates

Making Fuels Synthetically

Fundamental advances in Fischer-Tropsch chemistry may boost method's efficiency and popularity.

Quinone Ligand Ups Ante For Rhodium

Novel complexes expand role of premier catalyst metal, including applications in materials science.

In Pursuit of Synthetic EPO

Complex erythropoietin-like glycopeptides are made from scratch.

May 29, 2006

Science & Technology Concentrates

Fixing Phosphorus

Niobium complex allows MIT chemists to build compounds from elemental phosphorus.

The Power Of Procrastination

Caltech instructor and his comic strip champion a rethinking of the merits of putting things off.

Digital Briefs

New Software and Websites for the Chemical Enterprise.

May 22, 2006

Science & Technology Concentrates

Halogenases

Scientists are learning the structural and mechanistic secrets of the exquisitely selective enzymes that nature uses to install halogen atoms.

Analytica Meets For 20th Time

Attendance drops at biennial instrumentation trade show but still exceeds organizers' expectations.

Sugars Attach Nanotubes to Cells

Carbohydrate-coated carbon nanotubes mimic cell surfaces and interface with cells.

Imaging Spin Noise

New technique is analogous to magnetic resonance imaging, but without the radio pulses.

May 15, 2006

Science & Technology Concentrates

Archives For Africa

Royal Society of Chemistry offers free online access to its scientific journal archive.

Metallography

Striking photographs reveal metallic microscapes beautiful enough to hang in an art gallery.

May 8, 2006

Science & Technology Concentrates

Two-Body Solution

How dual-chemist couples found happiness, job satisfaction, and work/life balance.

Building On Success

Meeting of black chemists and chemical engineers highlights science, professional growth.

A Sweet Start For Inhalable Insulin

New approach to delivering insulin scores a first for both diabetes and pulmonary drug delivery.

Inside Instrumentation

Technology and Business News for the Laboratory World.

New Products

New and notable in the chemical industry.

May 1, 2006

Science & Technology Concentrates

Vintage Chemistry

The color changes that occur as wine ages are due to complex chemistry involving many compounds.

Big Molecules In Space

Prebiotic molecules in interstellar space are hard to detect and study, but astrochemists are closing in.

Digital Briefs

New Software and Websites for the Chemical Enterprise.

April 24, 2006

Science & Technology Concentrates

Digging Deeply Into The Past

Chemistry is increasingly helping archaeologists answer questions of what, where, and when.

Exploiting Polymer Nanostructures

Nanoscale control of polymer systems has been shown to influence macroscopic properties.

In Praise Of The Nose

Fragrance designer Michael Papas philosophizes about perfumes and reveals what goes into them.

From Manuscript To Journal Publication

Much of the process is automated, but technical editors still read every word of the manuscript.

April 17, 2006

Science & Technology Concentrates

Physicists Cast Anchor In Baltimore

Meeting spotlights novel electronic materials, antibiotic coatings, and an antiaging skin cream.

Planning Nanotech From The Ground Up

Scientists aim to design and produce safe, high-performance nanomaterials 'right the first time'.

Making Troubled Waters Potable

An inexpensive water treatment technology is making a difference in poor communities around the world.

What's That Stuff? Marshmallow

Gelatin has largely replaced the spongy confection's namesake, a plant-root ingredient.

New Products

New And Notable In The Chemical Industry.

April 10, 2006

Science & Technology Concentrates

Picking Apart Parkinson's

Researchers are seeking earlier detection and method to slow progression of disabling disease.

Journals Grapple With Ethics Issues

Scientific fraud and other serious ethical violations pose persistent questions, challenges for editors.

Deep-Sea Harvest

Marine microorganisms yield an abundance of new natural products with therapeutic potential.

A Taste Of Chemistry

Meeting highlights include ultrahydrophobic films, peptide antibiotics, gas chromatography detection.

Inside Instrumentation

Technology And Business News For The Laboratory World.

April 3, 2006

Science & Technology Concentrates

All That Glows

Bioluminescence provides practical applications while still remaining a mystery.

What's That Stuff? Beer

Brewing beer from cereals relies on a variety of biological, chemical, and physical processes.

Digital Briefs

New Software and Websites for the Chemical Enterprise.

March 27, 2006

Science & Technology Concentrates

Shedding Light On DNA Replication

Mechanistic studies fill holes in understanding of various aspects of DNA replication.

Storing Hydrogen In Polymer Pores

Polymers that inefficiently pack space adsorb significant quantities of hydrogen at 77 K.

Fullerene For The Face

Cosmetics containing C60 nanoparticles are entering the market, even if their safety is unclear.

March 20, 2006

Science & Technology Concentrates

Sprites Trigger Sky-High Chemistry

High-altitude lightning is visually stunning, but is it also a player in atmospheric chemistry?.

Molecules As Fossils

Mass spectrometry is helping paleontologists dig up molecular clues about prehistoric creatures.

Academic Chemistry After Katrina

Chemistry departments at New Orleans universities suffer less than some, but difficulties remain.

New Products

New and Notable in the Chemical Industry.

Science In India

Aided by the return of expatriates and ample money for R&D, India is building its drug discovery capabilities, fostering interdisciplinary science, and developing a vibrant postdoc culture.

Building R&D For Drug Discovery

Seasoned expatriates trickle back to help Indian pharmaceutical firms push into discovery research

Collaboration

Indian Pharma Bets On Links With Academia And Government

Bridges Wait To Be Built

India struggles to foster interdisciplinary science

Keeping Postdocs At Home In India

A vibrant postdoc culture could invigorate India's research climate, but recruiting remains difficult

A World Apart

Divergence of undergrad education and scientific research in India has been detrimental to both

A Funding Evolution

Some of India's scientists find research dollars easier than ever to obtain, but inequities remain

March 13, 2006

Science & Technology Concentrates

Supersize Enzymes Come Into Focus

Architectures of fungal and mammalian fatty acid synthases are determined at 5-? resolution.

Nanoparticles Form Diamond-like Crystals

Electrostatic interactions bring together oppositely charged nanoparticles in an unexpected way.

Enzyme Rescued for first time In Live Cells

Small molecules is used to partially restore lost activity of a disabled enzyme.

What's That Stuff? Motor Oil

Lubricant keeps car engines from clanging apart, sparks debates on how often it should be changed.

Inside Instrumentation

Technology and Business News for the Laboratory World.

March 6, 2006

Science & Technology Concentrates

Explaining C-H Bond Strengths

Alternative to hyperconjugation invokes steric strain, but not everyone is buying the idea.

Digital Briefs

New Software and Websites for the Chemical Enterprise

February 27, 2006

Science & Technology Concentrates

A Magnet For Talent

Singapore prepares to move up the R&D value chain by building a research infrastructure with both foreign and homegrown talent.

An Unlikely Center For Pharmaceuticals

India has skilled labor and China has raw materials, but big drug companies prefer Singapore.

Educational Alliance Takes Next Step

Singaporean universities and MIT launch second phase of their education and research partnership.

Sowing The Seeds Of Oriented Films

Technique allows systematic manipulation of pore orientation in molecular sieve thin films.

Trip Of A Century

Albert Hofmann, inventor of the mind-altering drug LSD, celebrates his 100th birthday

C&EN Talks With Haldor Tops?e

Veteran Danish catalysis developer's focus remains rooted in fundamental science.

February 20, 2006

Science & Technology Concentrates

Wiring Electronics With Nanotubes

Nanoscale carbon wire offers advantages as an electronic material in displays, flexible electronics.

New Journal Offers Open Peer Review

Biology Direct joins a small band of online journals that make their referees' reviews public.

Electrochemistry

Researchers are using electrochemical techniques to observe the chemistry of neurons in the human brain.

February 13, 2006

Science & Technology Concentrates

The Great Unplugging

Hunger for mobility energizes the battery business, drives efforts to develop longer lasting batteries.

Lithium-Ion Batteries

The Marketplace Beckons For More Innovation.

Naked-Eye Sensors Detect Anions

Thiourea-based colorimetric sensors recognize biologically important anions in aqueous solution.

Research Lab Disbanded

Dye derived from green henna leaves is used to decorate the body with intricate designs.

Radicals Tell Mice What's Up and Down

Reactive oxygen species are found to play a role in helping mice develop a sense of balance.

Inside Instrumentation

Technology and Business News for the Laboratory World.

February 6, 2006

Science & Technology Concentrates

The Secret Life Of Plant Crystals

Microscopic view of plant tissue reveals a hidden world of calcium oxalate crystals of diverse shapes.

What's That Stuff? Henna

Dye derived from green henna leaves is used to decorate the body with intricate designs.

January 30, 2006

Science & Technology Concentrates

Crystal Ball On The Environment

Detective work and expertise are used to evaluate environmental contaminants of emerging concern.

Shifting Sensibilities In Molecular Sensors

Molecular recognition arrays offer an alternative to lock-and-key approach.

What's Next In The Evolution Debate?

Dover ruling is a setback for intelligent design, but antievolutionists are pursuing other tactics.

Digital Briefs

New software and websites for the chemical enterprise.

January 23, 2006

Science & Technology Concentrates

Gentler X-Ray Spectroscopy

Symposium focuses on analytical applications of absorption and emission methods.

Seeking Chemical Clues To Earthquakes

Scientists are drilling miles into Earth to probe the chemistry and mechanics of the San Andreas Fault.

New Products

New And Notable In The Chemical Industry.

January 16, 2006

Science & Technology Concentrates

Bar Coding Life

A global project to create a new framework for identifying all biological species gains momentum.

Glassblowing

Trade may be in decline because of changing technologies and medical advances, but glassblowers still play a pivotal role.

January 9, 2006

Science & Technology Concentrates

Blocking Genome Gatekeepers

Scientists pin hopes on histone deacetylase inhibitors for cancer therapy, biological studies.

Ketenes Turn 100

Chemists gather to celebrate centennial of synthetically useful family of compounds.

Inside Instrumentation

Technology and Business News for the Laboratory World.

Polyurethane Foam

From furniture cushions to insulation, versatile polymer has found a world of applications.

January 2, 2006

Science & Technology Concentrates

Pacifichem Potpourri

Meeting highlights include magnetic wastewater treatment, potential peptide drugs, silole chemistry.

Cracking The Concrete Ceiling

Japanese government gets behind efforts to increase the number of women scientists in the country.

Salvaging NASA's Crashed Genesis Mission

After a year of cleaning up fragments of the solar-wind collectors, scientists are getting results.

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