DNA's regular structure and predictable chemistry make it an ideal building block for bottom-up fabrication. Scientists have been using it for years to build nanoscale cubes, cages, and octahedrons. Now, with his so-called DNA origami, Rothemund has taken DNA nanofabrication to a new level, creating DNA nanodesigns 10-fold more complex than any made previously. With DNA origami, Rothemund can knit the nucleic acid into any two-dimensional shape or pattern. Stars, snowflakes, and smiley faces just 100 nm wide are among his tiny creations. "Rothemund has taken a new step in DNA nanotechnology and has built an origami system that allows the formation of arbitrary patterns with what appears to be relatively little effort and expense," says New York University chemistry professor and DNA nanotechnology pioneer Nadrian C.
by Bethany Halford |
March 20, 2006