—Protein dance on nanoparticle surface revealed “NMR technique glimpses ubiquitin dynamics on nanoparticle” The growing use of nanomaterials in biomedical applications makes understanding nanoparticle-protein interactions an important goal. Nuclear magnetic resonance spectroscopy is a promising way to probe such interactions. But because of the huge size difference between nanoparticles and proteins, protein peaks disappear in nanoparticle NMR spectra, making the interactions invisible. G. Marius Clore, Vitali Tugarinov, and coworkers at the National Institute of Diabetes & Digestive & Kidney Diseases have now developed an NMR technique that can image protein dynamics on lipid-based nanoparticle surfaces (J.
by Stu Borman |
May 16, 2016