—Iridium Double Clutch Produces Triborylalkenes “Catalysis: Adding carbon monoxide mid-reaction switches gears for the catalyst, leading to a two-step, one-pot alkyne borylation/boronation” Tetrasubstituted olefins are important structural motifs in drugs and functional materials. Chemists have many ways to make them, including using polyborylated alkenes as intermediates. In exploring alternative routes to the borylated compounds, Oleg V. Ozerov of Texas A&M University and his colleagues previously reported the first example of dehydrogenative borylation of terminal alkynes, in which they used an iridium catalyst with a polydentate SiNN ligand and pinacolborane to make an alkynylboronate.
by Stephen K. Ritter |
October 12, 2015