—Probe Delivers Fluids, Light To Brain “Neuroscience: Thin, flexible optofluidic device causes minimal tissue inflammation” Collaboration between neuroscientists and materials scientists has yielded a new minimally invasive neural probe and wireless device that delivers liquid pharmaceuticals and light stimulation to brain tissue in mice and rats (Cell 2015, DOI: 10.1016/j.cell.2015.06.058). At about 80 µm thick and 500 µm wide, the soft, flexible polydimethylsiloxane (PDMS) probe caused a less severe inflammatory response than did conventional metal cannulas and optic fibers. The system, mounted on a rodent’s head, pumps fluids from four reservoirs through four 10-µm-wide channels deep into brain tissue.
by Judith Lavelle |
July 27, 2015