||Forged in St. Anthony's Fire: Drugs for migraine
Ergot, a potent neurotoxin and vasoconstrictor found in a
fungus that grows on rye, was one of the first effective
migraine medications and has been a springboard for
further migraine drug development.
||Restoring magic to the bullets
Humanized monoclonal antibodies (MAbs) are succeeding as
drugs where mouse MAbs failed. Fully humanized MAbs are in
the development pipeline, and therapeutic bispecific MAbs
are extending the versatility of nature's magic bullets.
||A conversation with Stelios Papadopoulos
A master biotech dealmaker talks about the difference
between science and Wall Street, pharma mergers, the risks
of biotechnology, job security, and what a scientist needs
to raise venture capital.
Listeria monocytogenes causes food poisoning that can be
fatal. Nevertheless, the unveiling of its life inside
infected cells has inspired scientists to develop Listeria
as a vehicle for vaccination against infectious disease