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  September 2003
 
 


September 2003 Table of Contents
Product Information

Featured Product: Mass Flow Sensors for GC, HPLC
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Mass Flow Sensors for GC, HPLCMass Flow Sensors for GC, HPLC

For more than 30 years, thermal mass flow measurements using coils around steel capillaries have been the standard in the precise measurement and dosing of mass flow rates.

Now CMOSens technology from Sensirion AG (Zurich, Switzerland) integrates this basic physical measuring principle in an extremely fast, miniaturized thermal sensor with all of the high-precision signal-conditioning circuitry on a single CMOS (complementary metal oxide semiconductor) microchip.

For liquid mass flow measurement in LC applications, lab-on-a-chip systems and liquid handling, CMOSens microchips can be placed in the position of being able to detect flow rates in the range of a few microliters or nanoliters per minute. Mounted on the outside of fused silica, PEEK, or steel capillaries, the highly sensitive CMOSens microchips detect the flow through the tubing material and a simple straight capillary forms the flow path. Further, by using this technology, great repeatability for analyses—the most important criterion in HPLC—is ensured. It works totally media isolated and with minimized inner volume, so the reliable monitoring of the process is guaranteed.

The fused silica-based, fully digital, calibrated, and temperature-compensated liquid flow sensor SLG1430 works with a repeatability greater than 0.8% of the measured value and achieves a fast response time of <50 ms. Moreover, the device offers resolutions of 0.5 nL/min and better. It is equipped with microfluidic connectors for OD360 capillaries and a digital RS232 interface. Ultra-fast response times in the millisecond range help users to monitor effects in their systems that they have not previously been able to observe.

Sensirion AG 248


More Products

Separation System.The CARR Powerfuge Pilot benchtop separation system expedites challenging liquid/solid separations before full process scale-up in the biotechnology, pharmaceutical, and specialty-chemical industries. Flow rates from 0.1 to 4 L/min and RCFs from 500 to 20,000 x g accommodate specific applications such as fermentation, vaccine production, plasma fractionation, and cell debris clarification.
Kendro Laboratory Products 230

HPTLC Plates.Macherey-Nagel has introduced Nano-ADAMANT plates, which feature a new organic binder system for a harder silica layer. Because of very high abrasion resistance, the formation of dust on the surface of the ADAMANT is minimized. The plate can be easily marked (e.g., with a lead pencil) for clear identification. Abrasion resistance prevents undesired changes or damage to the layer (thickness) during transportation and/or in handling.
Macherey-Nagel 231

HPLC Autosamplers.The Shimadzu SIL-10AF autosampler directly replaces the SIL-10A and includes a fast injection pretreatment routine that reduces sampling time by 30% with no loss of precision. The SIL-10AP is the prep version and comes standard with a 5-mL syringe and sample loop for large-volume injections.
Shimadzu Scientific Instruments 232

Gas Generator.The model N2-15 is a self-contained membrane nitrogen generator that produces 99% pure nitrogen with pressures up to 100 psig. High- and low-pressure compressors filtered by high-efficiency coalescing filters remove all contaminants down to 0.01 µm. Hollow fiber membranes subsequently separate the clean air into a concentrated nitrogen stream and oxygen-enriched permeate stream, which is vented from the system.
Parker Balston 233

Mixer Mill.Retsch introduces the MM 301, a model particularly suited for dry and wet grinding of small quantities, as well as mixing and homogenizing powders and suspensions. The MM 301 features a quick-action clamp on the grinding jar, which ensures easy handling and optimizes reproducibility of the sample preparations.
Retsch, Inc. 234

Software.NuGenesis Technologies Corp. has released v6.01 of its scientific data management system (SDMS). Important new features have been added to enhance support for users of Apple Macintosh computers running Mac OSX 10.2.5. Along with the ability to restore raw data files from a Macintosh, report summaries and other “human-readable” data can now be viewed in SDMS.
NuGenesis Technologies 235

Balances.The Ohaus Analytical Plus models feature a lockout switch to safeguard the user’s pre-set parameters and motorized internal calibration at the touch of a button. These balances also offer 11 weighing modes to meet a variety of applications needs; full GLP protocol for users involved with quality systems like ISO 9001; and an RS232 bidirectional interface to facilitate easy integration with peripherals.
Ohaus 236

GC Ovens.By heating only the GC columns rather than the surrounding air and oven walls, Antek’s 3600 Series Microwave GC column oven provides 6 °C/sec heating and over 240 °C/min cooling rates, to speed every analysis. The Dual-Oven Microwave GC (Model 3602) converts an existing one-analysis-at-a-time GC into a simultaneous dual analyzer that can use concurrent yet different temperature pro grams, doubling GC capability.
Antek Instruments 237

Thermo Prep Ovens.Models Büchi B-540 and Automatic B-545 provide temperature ranges from ambient to 400 °C. Both ovens can provide simultaneous melting point determinations of two boiling samples or three melting points and are equipped with viewing chambers for visual determinations.
Brinkmann Instruments 238

Chillers.Upgraded midsize industrial chillers are available in various sizes, configurations, and capacities. These handy rugged chillers provide convenience and can be equipped with shutoff valves, tank level indicators, and flow meters. They provide cooling for plastic molding equipment, lasers, printers and electronics, and other process equipment.
Polyscience 239

Gas Purifiers.The Valco helium purifier provides point-of-use gas purification of helium or other noble gases, such as Ar, Ne, Kr, and Xe, to sub-ppm levels of reactive gaseous impurities. The nitrogen purifier does the same for nitrogen. The gas purification substrate in Valco gas purifiers is a non-evaporable heat-activated gettering alloy, in a welded assembly for safety.
Valco Instruments 240

Mixers.These modular units can be customized to almost any size. Containing a high-torque stepping motor for precise control for demanding applications, the high- or low-speed mixing (orbital) assists in obtaining repeatable mixing results. Some applications include process development and combinatorial chemistry. Mixer is controlled through a PC with Glas-Col’s Labnetix software or with the aid of a virtual instrument for Labview.
Glas-Col 241

Circulator.The Huber Unistat 169W offers an operating temperature range of -60 to 200 °C with increased cooling of 40 kW at -40 °C. The 169W is hydraulically sealed to provide temperature control for a variety of processes and applications. Its low fluid volume and high cooling power density provide fast rates with less power.
Caron Products 242

Analyzer.The Pegasus 4D with advanced ChromaTOF 2.0 software fully integrates four dimensions of problem-solving capabilities to deliver better information from the most challenging chromatographic analyses. It combines the chromatographic resolving power of GCxGC separations and the analytical resolving power of the Pegasus III GC-TOFMS. The automated Peak Find and Mass Spectral Deconvolution algorithms of ChromaTOF simplify GCxGC data collection and processing.
LECO Corp. 243

Spectrometer.The PANalytical Epsilon 5 is an energy-dispersive X-ray fluorescence (EDXRF) spectrometer for low-level detection of heavy elements. It detects elements from sodium to uranium in solid, pressed-powder, granule, liquid, thin-film, and loose material samples. Measurements can be performed in a vacuum or helium atmosphere.
PANalytical 244

X-ray Optics System.The Rigaku HomeLab LightSource is designed to approach the intensity of a synchrotron bending magnet beamline in a “home lab” environment. Combining Osmic, Inc.’s VariMax optics with the Rigaku FR-E X-ray generator, this system has more than twice the usable X-ray flux of previous generation CMF/FR-E systems, and also features an adjustable beam for resolving cell lengths in excess of 450Å.
Rigaku/MSC 245

Spectrometer.Jobin-Yvon’s GD-PROFILER is dedicated to the surface, depth profile, and bulk analysis of almost any material or coating—conductive or nonconductive. It can simultaneously analyze up to 64 elements including the gases H, O, N, and Cl. It features the highest optical resolution available with a 1-m polychromator and an optional 1-m monochromator.
JY Horiba 246

Elemental Analyzer.The Multi EA 3100 model achieves detection limits of 10 ppb for sulfur determination by UV fluorescence and 50 ppb for nitrogen determination by chemiluminescence. With luminescence methods, there is no interference between sulfur and nitrogen in case of low sulfur and high nitrogen contents. The detection limit for chlorine determination is 100 ppb.
Analytik Jena 247

Counting Scales.The DIGI DC-200/300 Series counting scales provide precision and accuracy for stockroom inventory, receiving parts verification, parts scanning, and counting and labeling applications. With three RS-232 interfaces and Ethernet connectivity, the DC-200/300 Series allows users to transfer information to a database for real-time inventory and eliminate handwritten errors.
Rice Lake Weighing Systems 249

Detector.ESA’s Chromachem Evaporative Light Scattering Detector (ELSD) for use with HPLC provides universal detection of nonvolatile compounds. The modular ELSD features higher peak resolution, a sophisticated microprocessor, small footprint, RS232 interface, and a larger graphic display with more information.
ESA, Inc. 250

Calibration Service.Temperature calibrations are provided for resistance-type measuring devices like liquid gas thermometers and thermistors. Fixed-point primary calibrations and secondary calibrations can be performed for less accurate temperature devices. Calibrations can be tailored to customers’ specifications from -196 to 700 °C in an ISO/IEC 17025-compliant setting.
Troemner 251

Evaporator.The Zipvap 18 provides sample preparation by nitrogen evaporating or concentrating 1–18 samples sized from <1 mL to 100 mL. It has a swing-up-and-away manifold that is also height adjustable. It comes with individual fine-needle valve flow control for each of the 18 positions and includes a triple block heater.
Zanntek Scientific 252

ICP Chamber.Glass Expansion has developed the Helix user-friendly nebulizer fitting. Helix’s main features are: no more tedious o-ring replacement; totally inert interior surface; smooth nebulizer insertion and removal; special release/lock mechanism to seal the chamber; and positive stop to ensure correct nebulizer position.
Glass Expansion, Inc. 253

Strip Chart Recorder.The DACS Digital Strip Chart Recorder is a scaled-down version of the GOW-MAC DACS Chromatography Data Handling Software. This device provides the same information as conventionally larger models, including peak area, retention times, and chromatogram without having to perform a calibration. Displays signals in real-time and via ACSII connection data that can be imported and exported for processing.
Gow-Mac 254

Imaging System.PRISm is a portable imaging system that provides hyperspectral imaging that is ideal for in vivo Raman imaging for medical applications such as surgery and dermatology, as well as other demanding applications, including HTS. It can also be used in process Raman applications to monitor numerous reaction control points simultaneously.
JY Horiba 255

Analyzers.The Konelab series provides complete automated analysis of routine wet chemistry/photometric tests of water and wastewater samples. Up to 84 samples, plus six STAT samples, can be loaded into the analyzer without interrupting ongoing analysis. With no stabilization time or pump tubes to change, up to 600 tests can be completed without any intervention from the analyst.
EST Analytical 256

Monochromator.The TEEM system has been developed to detect sub-ppb levels of explosives, environmental contaminants, compounds associated with chemical warfare agents, and bacterial spores. Using a patented ionization technique, it will eliminate spectral interferences, clearly illuminating minute traces of specific compounds in samples of dirt, packing foam, and other substances. It also forms negative ions without using a moderating gas and produces an electron beam with an electron energy that can be adjusted from 0 to 25 eV.
JEOL 257

Distillation System.The Midi-Vap 2000 supports semiautomatic colorimetry methods for drinking, surface, saline, and domestic and industrial wastewaters, using up to 10 economically sized samples. The units meet EPA/600/R-93/100 methods for the determination of inorganic substances in environmental samples and are available in three complete component assemblies to process water samples for ammonia, cyanide, and phenols, or in a combination assembly that permits processing of all three.
Kimble Kontes 258

Columns.These packed single-use Chroma bond columns are designed for automated systems and upscaling procedures. They include alternative Chromabond flash cartridges for the automation systems of Jones Chromatography/IST, ISCO, Biotage, and Gilson. The selection of column systems, sorbent weights, and stationary phases results in a great deal of flexibility in process development work.
Machery-Nagel 259

Data System.Atlas 2002 R2 includes a series of features to offer easy retrieval and reprocessing capabilities for chromatographic data from other CDSs previously archived in a normalized data format, improved instrument management and control, and enhanced file security. It supports the import of CDS data previously exported and stored in the generalized analytical markup language (GAML) format. It also allows the importation of an entire Atlas workbook as a GAML file, including raw data, processed data and results, methods, reports, calibration details, the audit trail for reprocessing, and further reporting and subsequent re-archival.
Thermo Electron 260

Evaporators.These rotary evaporators are available with vertical or diagonal condensers, and each features a stirred heating bath, an ergonomic stand for easy raising and lowering, a rotary drive motor, and a full set of glassware. The rotovaps were engineered for the highest safety requirements and operational flexibility. With numerous glassware attachments available, the units can accommodate a wide variety of applications.
IKA Works 261

Data System.The CLASS-VP v7.2 client/server chromatography data system has built-in features to ensure compliance with 21 CFR Part 11 requirements. Enhancements include a signing authority hierarchy to enforce proper application of electronic signatures and optional comments for e-signatures, thin client interaction to simplify validation of large software deployments, and activity logs and audit trails. It supports a wide range of HPLC and GC systems, including digitally configured injection and detector modules.
Shimadzu 262

Sample Prep.The Captiva starter kit for plasma protein precipitation and filtration is available from Varian. Each kit contains a vacuum collar, filtration plates, 96-well plate seals, collection plates, and collection plate covers that can be pierced.
Varian 263

Flask.The MantaRay is a single-use, disposable, pre-sterilized spinner flask for cell cultures that is designed to be a cost-effective alternative to glass spinner flasks. It consists of a freestanding plastic container with a fill cap and sealed ports for pumps or injectors. It has a working volume range of 0.4–1 L. It also includes an integral stirring mechanism, which is designed to efficiently mix at low speeds while avoiding damage to fragile cells.
Wheaton Science 264

Software.This control software is used for a range of centrifugal evaporators that have an “Auto Stop When Dry” function that provides significant productivity savings by enabling the solvent removal system to determine automatically when the last samples are dry.
GeneVac 265

Scale.Standard features on these precision lab balances include autocalibration, a 17-mm-high LCD, a weight below hook, stainless steel pans, programmable auto shutoff, a security bracket, a stability indicator, and a low-battery indicator. It is a 120 V, AC and includes a 50/60-Hz adapter. The scale measures 6 x 2.4 x 8 in.
Scientifics 266

Thermal Analysis.HyperDSC is a thermal analysis method for material characterization that delivers sensitivity and insight into materials processes that cannot be obtained with differential scanning calorimetry methods. It provides sample information within seconds, significantly increasing throughput in the polymer and pharmaceutical industries. It is an ideal method for the polymer, pharmaceutical, life sciences, and forensics industries in applications ranging from polymorphism to thermal screening of enzymes to high-throughput screening and characterization of microgram quantities of materials.
PerkinElmer 267

Trace Analysis.This PC-controlled system for trace metal analysis optimizes voltammetry measurements through mechanical stability and signal-to-noise ratio software capabilities. The Model 757 is suited for both simple routine and research analyses and for running numerous current-measuring techniques with automatic options. Evaluation and calibration can be achieved by standard addition or calibration curve, either manually or automatically.
Brinkmann 268

Indicator/Controller.Designed for multiscale, data acquisition, batching, and industrial automation applications, the 920i programmable indicator/controller features a large LCD screen that can be custom-configured with weight character sizes up to 1.2 in., active bar graphs, status messages and ions, operator prompts, and multiple soft-key functions. The 920i allows up to 4 scale displays with legal-for-trade information, or up to 32 weight-only displays that can include individual scales and any combination of totalized scales.
Rice Labs 269

Troughs.These 8- and 12-channel reservoir troughs are designed to minimize dead volume while adding standards, wash rinses, or reagents in high-throughput cleanups. The V-bottom design has a 200-µL residual volume. The 8-channel trough is made from high-impact polystyrene and has a 1–7-mL capacity per channel. The 12-channel trough is made from clear PETG and has a 1–3-mL capacity per channel.
Bio Tech Solutions 270

Reagents.The Mpak Reagent package is a closed-system delivery technology that prevents contamination while it simplifies analytical testing. The premixed custom reagents are sealed in a flexible ultrapure bag.
Metrohm Peak 271

Circulators.More than 100 different refrigerated and/or heating baths/circulators are available that feature active cooling at any selected temperature and work at a variety of voltages without a loss in overall performance. There is a 2-year warranty on parts and labor.
Julabo 272

Moisture Analyzer.The compact Sartorius MA45 will perform most moisture analyses in >15 min instead of the hours typical with oven-drying methods. The analyzer features a design that is specifically engineered for food, pharmaceutical, and chemical applications, with a special version available that meets the requirements of the FDA and HACCP protocols. It offers a manually adjustable, semiautomatic mode in addition to the timer mode and a fully automatic mode of end-point determination.
Sartorius 273


Literature

Catalog.The SGE Analytical Science catalog includes a comprehensive range of syringes, tubing, GC, LC, and MS products such as capillary LC columns and accessories, metal ferrules for GC-MS systems, and electron multipliers. Handy trouble-shooting tips and maintenance guides are also included. For a free copy, call 800-945-6154, e-mail usa@sge.com, or visit www.sge.com.
SGE 274

Demo CD.Leeman Labs’ demonstration CD showcases its inductively coupled plasma optical emission spectrometry, the Prodigy High Dispersion ICP. Prodigy incorporates a large-format, programmable array detector (L-PAD) and an advanced high-dispersion Echelle spectrometer. The CD allows anyone in the market for an ICP to “test drive” the Prodigy.
Leeman Labs 275



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