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Table of Contents

January 1998
Volume 7, Number 1

FEATURES

27 SFC BOOSTS DRUG DISCOVERY AND OTHER PROCESSES
Both single-column and packed-column SFC are useful tools in drug discovery; the latter is an official method of the Swiss Pharmacopoeia
Julie K. Poudrier
34 EFFORTS IN COMBINATORIAL CHEMISTRY
The research shifts toward designing focused libraries that are more interactive and multidisciplinary to facilitate drug discovery
Joanna McNeal

DEPARTMENTS

8 UPDATE
10 LETTERS
11 COMPUTERS IN CHEMISTRY
Reshaping the drug discovery environment
Michael Sullivan
16 KEEPING UP
23 CHEMISTS AT WORK
Scientific leader or technical manager?
Brian R. Strohmeier
39 PERSONAL BUSINESS
Hang up on phone fraud
Dickinson J. Miller
43 HEALTH PERSPECTIVES
Lifestyle changes and motivation
Trevor Smith
49 REGULATIONS AND YOU
Don't let the year 2000 bug bite your lab
Helen Gillespie
55 THE WAY WE WERE
Teflon: The case of the not-quite-empty cylinder
David M. Kiefer
59 NEW PRODUCTS
68 COMMENT
Welcome
James F. Ryan
Cover photo: Tripos