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Table Of Contents: Volume 83, Number 49: December 5, 2005

Cover Story

Pharma Reformulates

Sales grew in the past year, but the pharmaceutical industry saw many major products come under fire and was challenged in moving new ones forward.

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News of the Week

Merck Schedules Big Shake-Up

Job cuts and plant closings are among initial steps in restructuring

Carbon Emissions Trading Picks Up

As UN conference gets under way, firms eye emissions profit potential.

Canada Hosts UN Climate meeting

Industry wants Congress to end drilling restrictions to increase natural gas supplies.

Protein's Lipid Coat Revealed

High-resolution structure of membrane protein captures its lipid environment.

Open Access

Britain's Royal Society says hasty moves to open-access publishing could be harmful.

Tracking Cellular Machine Assembly

Technique observes how parts of a macromolecular complex bind in real time.

Modifying DNA

Chemical strategy provides new way to derivatize DNA sequence specifically.

Mammalian Amyloid Has Useful Role

Fibers that have amyloid structure serve as templates for melanin biosynthesis.

Plant Security

New Jersey s acting governor signs off on the nation s first set of chemical plant security standards.

Business (Suscriber Content)

PerkinElmer Hones Life Sciences Plan

With sale of fluid sciences business under way, instrument maker focuses on life sciences.

Steady R&D For Agchem

Discovery and development account for half of spending by top crop protection chemical companies

C&EN Talks With Agnes Varis

A champion for the generic drug industry deftly mixes business and Democratic politics.

Government & Policy (Suscriber Content)

Nanotech's Safety Risks

House Science Committee holds hearing to ensure risks of small technology aren't being ignored.

Push On Hill For Fuel Independence

Lawmakers seek to cut U.S. demand for oil, boost biofuels and alternative-technology vehicles.

Science & Technology (Suscriber Content)

Long Live RIKEN

At 88, Japan's premier research institute thrives but struggles with global isolation.

New Products

New And Notable In The Chemical Industry.

Books

ACS News

Awards

Editor's Page

The Departments

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COVER: Structure of Lipitor superimposed on Stockdisc image.

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