Table of Contents
Volume 85, Number 9: February 26, 2007
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Table of Contents
- News of the Week
- Business
- Government & Policy
- Science & Technology
- Awards
- Books
- Editor's Page
- The Departments

Cover Story
Biopharma
Hsp90, a molecular chaperone protein, has come into its own as a target for cancer therapies.
COVER: Kosan's second-generation inhibitor of the protein Hsp90 is firmly anchored in the pocket created by a portion of Hsp90 and ATP. Kosan Biosciences

News of the Week
Halogen-Induced Cyclization
Long-sought enantioselective reaction leads to halogenated steroidal compounds.
Shire Acquires New River
Shire buys partner to have ADHD drug all to itself.
Detecting Nuclear Materials
Two agencies unite to spur academic research in breakthrough technologies.
Molecular Close-Up
Images show motions of single, confined molecule.
F. Albert Cotton Dies
Inorganic chemistry pioneer was first to show existence of metal-metal quadruple bond.
Rail Strike Hits Canadian Firms
Chemical company executives call on Canadian government to act.
Largest Chemically Made Protein
HIV protease analog assembled using kinetic ligation approach.
Columbus' Silver Mining Debunked
Chemistry rewrites history of precious-metal processing in New World.
Environmental Justice
Hazardous waste facilities are often sited in poor, minority areas, study shows.
Business
Business Concentrates
Brushing Up On Plant Riches
Phytochemicals get boost from advanced chemical analysis, synthesis.
Chemical Earnings Show Strong Rise
But year-to-year fourth-quarter performance masks slowing of growth as 2006 ended.
Pharma Takes Action
Restructuring in the face of disappointing financial results obscures improving pipelines.
Biotech Milestones
Product successes in 2006 translate into growing sales and profits for biopharmaceutical firms.
Government & Policy
Government & Policy Concentrates
Industry Adapts To New Congress
Business groups maintain ambitious agenda but face tough battles on Capitol Hill.
Power Struggle
Lawmakers probe Bush directive, fearing decrease in their influence on regulations.
Science & Technology
Science & Technology Concentrates
Quinine Revisited ... Again
Historical research helps untangle the complex mythology of quinine synthesis.
Avoiding Global Collapse
Chemists have a vital role to play in achieving sustainability.
Awards
Call for Nominations for Linus Pauling Award
2007 Midwest Award Nominations
Nominations Sought for Citation for Chemical Breakthroughs
Nominations Wanted For Paul Marks Prize
Ryoji Noyori Prize goes to Evans; 2007 Nominations Sought
Books
Science News As An Object of Study
A seasoned science writer analyzes how news is made.