The President's Budget

Quote of the Week
"Here, you have to order chemicals well in advance, and I mean well in advance. You're lucky if your chemicals arrive in four months."
TEVITA VORO, CHEMISTRY LECTURER, UNIVERSITY OF THE SOUTH PACIFIC, LAUCALA CAMPUS, FIJI – p. 53
February 28, 2011
In This Issue:
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Highlights

Cover Story
Federal Budget 2012
President Obama provides targeted gains for science. (pp. 13-25)

Business
Rebuilding The Supply Chain (Member Content)
At Informex, suppliers worked to create new and stronger ties with customers. (pp. 19-22)
» Pharmaceutical Roundtable Shares Assessment Tool With Suppliers

Meetings
Pittcon 2011 In Atlanta (Member Content)
Gathering aims to be the premier annual conference and exposition on laboratory science. (pp. 66-67)
Table of Contents
Cover Story
More Support For Science pp. 13-14
President's 2012 budget proposal provides continued growth for science.
NSF: President Keeps Agency On Doubling Track pp. 14-15
NIH: Agency Growth Matches Biomedical Inflation Rate pp. 15-16
Defense: Science And Technology Funding Is Down p. 16
DHS: Additional Funds For National Security R&D pp. 16, 18-19
Energy: Support Up For Renewable Energy pp. 19-20
Commerce: Request Provides Gains For Laboratory Services pp. 20-22
NASA: Funding Is Flat, But Earth Science Programs Grow pp. 22-23
Agriculture: Research Funds Are Down p. 23
EPA: Budget Cut, But Gains In Select Areas pp. 23-24
Interagency Initiatives: Education, Climate Science, And Nanotech All Grow p. 25
News Of The Week
House Slashes Federal Funding p. 7
Congress: Senate, House budget battle could lead to government shutdown.
Scripps Changes Leadership p. 8
Biomedical Research: Richard Lerner will step down as president to be succeeded by Berkeley chemist Michael Marletta.
Takeda Splurges On Research p. 8
Pharma R&D: Japanese firm opens $1.8 billion center.
Chemists Join Wisconsin Budget Battle p. 9
Worker's Rights: Bill to limit collective bargaining for state employees sparks widespread protests.
Gilead Sciences To Buy Calistoga Pharmaceutical p. 9
Acquisitions: Deal adds key oncology compound to acquisitive firm's pipeline.
Pushing For A Phthalate p. 10
European Union: Industry wants to continue use of DEHP, which is facing a ban under REACH.
The Case Of The Missing Xenon p. 10
Noble Gases: First XeO2 synthesis could provide the final clue to one of Earth’s geochemical mysteries.
Poor Management Led To BP Spill p. 11
Technical Findings: Long-running problems caused Gulf spill, commission finds.
Big Enzyme Takes On Tiny Target p. 11
Catalysis: Modifying a huge active site enables conversion of methane to methanol.
Business

Rebuilding The Supply Chain pp. 28-31 (Member Content)
At Informex, suppliers worked to create new and stronger ties with customers.
Green Chemistry: Pharmaceutical Roundtable Shares Assessment Tool With Suppliers pp. 30-31 (Member Content)
Chemical Earnings Gain Steam pp. 32-34 (Member Content)
As the economy heats up, demand for chemicals spreads to all regions and sectors.
Pharma's Next Transformation pp. 36-38 (Member Content)
Companies continued to overhaul R&D amid tepid fourth-quarter results.
Little-Known HEC Beefs Up R&D pp. 40-41 (Member Content)
From 26 scientists in 2005, Chinese drug firm expects its research payroll to hit 1,500 by next year.
Assessing The Cost Of Greenhouse Gases p. 43
Climate Change: Two studies try to measure long-term impact on business and investors.
Business Concentrates pp. 26-27 (Member Content)
- Mideast Unrest Leads To Plant Shutdowns
- As Libya heads toward civil war, owners of chemical and oil operations in the country have taken steps to safeguard employees and assets...
- Chinese Firm To Make Ethylene Glycol
- Japanese firms Ube Industries and HighChem have licensed their process to make ethylene glycol from...
- Kemira Will Expand Coagulants In Europe
- Kemira will spend about $55 million to build coagulant plants adjacent to Bayer isocyanate facilities...
- BMW To Wrap Electric Cars In Carbon Fiber
- German automaker BMW says its new BMW i series electric cars, scheduled for launch in 2013....
- Dow, Rusnano Mull Nanotech Projects
- Dow Chemical and Russian Corp. of Nanotechnologies (Rusnano) will consider investing together...
- Abengoa Advances Cellulosic Ethanol
- Spanish alternative energy firm Abengoa has established an enzyme research program to increase yields...
- Solvay Buys Fluorspar Mine
- Solvay has acquired a fluorspar mine in Chiprovtsi, Bulgaria, not far from the Serbian border...
- Thermo Fisher Sells Off Two Businesses
- Thermo Fisher Scientific has signed agreements to sell its Athena Diagnostics and Lancaster Laboratories businesses...
- Forest Labs To Buy Clinical Data Inc.
- Looking to acquire new products that will offset declining revenues from drugs facing patent expirations...
- CO2-To-Plastics Plant Starts Up
- Bayer has started up a pilot plant in Leverkusen, Germany, to make polyether polycarbonate polyols...
- Kyowa Hakko Kirin Nabs ProStrakan
- Kyowa Hakko Kirin has agreed to pay roughly $470 million for Scottish specialty pharmaceutical firm ProStrakan Group...
- AstraZeneca To Build Russian Pharma Plant
- AstraZeneca will invest more than $150 million to build a drug production facility...
- GSK Cuts Jobs In North Carolina
- As GlaxoSmithKline retrenches its early-stage research, it is shedding several dozen clinical development jobs...
- Business Roundup
- Valspar, Bruker, Rhodia, Amyris, LanzaTech, Vical, Monsanto, Carbogen Amcis, Viropro...
Meetings
Pittcon 2011 In Atlanta pp. 66 - 67 (Member Content)
Gathering aims to be the premier annual conference and exposition on laboratory science.
2011 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community.
This Week Online
Government & Policy

FDA Budget Set To Expand p. 45 (Member Content)
President requests 29.3% boost for agency in fiscal 2012.
Diversifying Chemistry Faculty p. 46 (Member Content)
Workshop examines diversity inequity in academia.
Government & Policy Concentrates p. 44 (Member Content)
- EPA Limits Emissions From Industrial Boilers
- EPA last week issued final standards to curtail emissions of mercury, soot, and other pollutants from industrial boilers...
- Supreme Court Curbs Lawsuits Over Vaccines
- The Supreme Court ruled last week that a federal law prohibits product liability lawsuits against pharmaceutical companies for the rare but serious side effects...
- EPA Updates Pesticide Use Data
- EPA has released its latest estimates of U.S. pesticide sales and usage, for 2006 and 2007...
- Lower Fees Proposed For Rail Complaints
- The Surface Transportation Board (STB), is proposing to significantly reduce the fees it charges shippers...
- NIH Advisory Board Okays Reorganization
- NIH is forging ahead with its decision to abolish the National Center for Research Resources (NCRR) to make way...
» more government & policy news...
2011 ACS National Award Winners pp. 58 - 65 (Member Content)
Recipients are honored for contributions of major significance to chemistry.
- Awards: February 28
- Arthur C. Cope Award: Nicholas J. Turro
- Arthur C. Cope Scholar Awards: Zhenan Bao
- Arthur C. Cope Scholar Awards: Martin D. Burke
- Arthur C. Cope Scholar Awards: David Crich
- Arthur C. Cope Scholar Awards: Vy M. Dong
- Arthur C. Cope Scholar Awards: Craig J. Hawker
- Arthur C. Cope Scholar Awards: Seth R. Marder
- Arthur C. Cope Scholar Awards: Tobin J. Marks
- Arthur C. Cope Scholar Awards: Keiji Maruoka
- Arthur C. Cope Scholar Awards: Andrew J. Phillips
- Arthur C. Cope Scholar Awards: Suzanne Walker
- Hackerman Award To Jason Hafner
- Victor McCrary Named Scientist Of The Year
- Hurvitz And Wilchek Win Israel Chemical Society Medal
- Bill Dellinger Receives Technician Award
- Radding Award Seeks Nominations
- ACS Building Garners Green Award

Social Networking And C&EN
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Science & Technology

Navigating Nagoya pp. 50-51
Natural product hunters prepare to adapt to new biodiversity treaty.
Science & Technology Concentrates pp. 48-49 (Member Content)
- Sequestered Antibiotics
- Shuttling drugs away from their intended targets can sometimes transform them into good antimicrobials.
- A Revised Picture Of Deep-Earth Sulfur
- Under extreme conditions, sulfur may exist as S3-, rather than the presumed sulfide and sulfate species.
- Picking Prion Infectivity Apart
- New research suggests that infectious protein misfolding and Prion diseases’ neurological toxicity are independent processes.
- Iron(V) Nitride Mimics Nitrogenase Activity
- Chemists have isolated a rare Fe≡N complex and show that it readily produces ammonia.
- Catalytic Methanol Coupling Achieved
- An iridium complex catalyzes the direct C–H functionalization of methanol, a first for the single-carbon compound.
- Fish Poop Establishes A Geologic Record
- Scientists find that the aquatic vertebrates generate a large portion of the carbonate mud that deposits on the ocean floor.
- Palladium-Allyl Bridges Snatch CO2
- Unusual double-bridging complexes reveal their ability to insert CO2 and form carboxylates.
- Peptide Induces Hair Regrowth In Mice
- Astressin B helps genetically altered mice to regain skin pigmentation and regrow nearly all their hair.
» more science & technology news...
ACS News
IYC Profile: Fiji p. 53
For Fijian ACS member Tevita Voro, living in paradise can have its challenges.
ACS Updates Its Policy Statements pp. 54-56
Society calls for action on job creation, chemicals management, and climate change.
Policy Priorities: Current ACS Position Statements pp. 54-55
ACS Committees Seek Member Input On Policy Statements Web Exclusive
ACS Introduces Middle School Chemistry Curriculum p. 57
ACS Offers Funds For International Research Travel p. 57
Welcome: ACS hosted a reception for new officers. p. 57
Editor's Page
A Fundamental Divide p. 3
The Departments
Letters pp. 4-5

Newscripts p. 72
Chemistry Kit Chemophobia, Goof-Proof Golf Balls
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Environmental SCENE News
Fertilizer May Help Bacteria Slip Into Groundwater
Water Safety: High phosphate levels allow deadly microbes to pass through soil.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Sunlight Is An Effective Disinfectant
Public Health: Field work shows that a cheap water treatment method improves children's health.
House Takes Aim At Clean Air Act
Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.
Analytical SCENE News
New Method Isolates Membrane Proteins
Protein Purification: Technique separates proteins on a lipid bilayer.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Mapping Drugs In Human Tissue
Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.
Skeletons Come To Light
Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.
Analyzing Nuclear Processes
ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.
JACS Research In C&EN
Indole Changeup Yields Elusive Alkaloid
ACS Meeting News: Cyclization and nitrene insertion star in synthesis.
Prefab Synthesis Moves Ahead
Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.
Multiple Bradykinin States Revealed
The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.
Scaling Up The Axinellamines
A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.
A Revamped Vancomycin
Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.
CENtral Science
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