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Global Top 50
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Quote of the Week

"Sometimes it's the wacky science that you most don't want to miss supporting."
FRANCIS S. COLLINS, DIRECTOR, NATIONAL INSTITTUTES OF HEALTHp. 32

July 25, 2011

In This Issue:

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October 24, 2011 Issue
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October 3, 2011 Issue

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Highlights

Cover Story

Global Top 50

Chemical producers show surprisingly good profits soon after the recession. (pp. 12-15)

Science & Technology

Biomarkers Wanted

Discovery of potential diagnostic tools has been plagued with problems. (pp. 40-43)

Career & Employment

Expats In China

International assignments are returning, but with far fewer perks. (pp. 49-50)

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Table of Contents

News Of The Week

One Home For Various Guests p. 7

Supramolecular Chemistry: Chemical cage captures a variety of compounds, regardless of charge.

Taking Home The Gold p. 8

Academics: U.S. high school students earn two gold and two silver medals at International Chemistry Olympiad.

Ecolab To Buy Water Firm Nalco p. 8

Specialties: Transaction will create a leader in water treatment and cleaning products.

A Personal Meter For Everything p. 9

Sensors: System allows glucose monitors to measure other analytes.

Sweet Biopolymers Deal p. 9

Mitsui & Co., Dow Chemical joint venture in Brazil will be based on sugarcane.

Seattle Genetics Hits A Key Target p. 10

Pharmaceuticals: FDA panel gives thumbs up to antibody-drug conjugate.

The (Synthetic) Nose Knows p. 10

Bioelectronics: Chemical sensor combines olfactory proteins and carbon nanotubes to mimic biology.

Blueprint For Science Education p. 11

Curriculum: Framework is supposed to yield national teaching standards by 2012.

Slate Set For ACS Fall Ballot p. 11

Election: Candidates for president-elect, director-at-large, and district III and VI directors.

Business

Paying Attention To Manufacturing pp. 18-22 (Member Content)

Consortia aim to bridge the gap between drug development and manufacturing with a technology and engineering focus.

China Draws Catalyst Suppliers pp. 24-26 (Member Content)

Technology providers see opportunity as China seeks to make better plastics.

Business Concentrates pp. 16-17 (Member Content)

Career & Employment

Expats In China pp. 49-50

International assignments are returning, but with far fewer perks.

This Week Online

Meals Modify Proteins

Proteomics: Levels of protein acetylation may change in response to feasting or fasting.

How To Become A Video Star

C&EN's YouTube channel is collecting videos from chemists around the world. Contributing Editor Aaron Rowe explains the easy steps behind an effective video.

A Tragedy And Synthetic Marijuana

C&EN blogger David Kroll explains the origins of synthetic marijuana products, their intense psychoactive effects, and how governments are trying to regulate them.

Government & Policy

Preventing Disaster pp. 30-32 (Member Content)

Chemical industry seeks regulatory certainty in antiterrorism standards.

Aiding Innovation In Tough Fiscal Times pp. 34-35 (Member Content)

Experts warn that scientific creativity in the U.S. will decline without adequate funding.

Insights: Bidding Adieu To The Shuttle p. 36 (Member Content)

Program ends after 30 years, leaving a mixed legacy.

Government & Policy Concentrates p. 28 (Member Content)

ACS Comment

Meeting The Challenges Of National Meetings p. 46 (Member Content)

ACS News

IYC Profile: Ghana p. 47

David Dodoo studies the environmental impact of mining on this West African nation.

Facebook

Social Networking And C&EN

Social Networking And C&EN

You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.

Science & Technology

Biomarkers Wanted pp. 40-43

Discovery of potential diagnostic tools has been plagued with problems.

More Than Just Cancer: Some Biomarkers Move Toward Validation p. 43

Fishing For Biomarkers Web Exclusive

Why Water Fills Nanotubes p. 44 (Member Content)

Researchers probe origin of puzzling phenomenon and discover emptying, too.

Science & Technology Concentrates pp. 38-39

Meetings

2011 C&EN Calendar Web Exclusive

C&EN's latest list of meetings and events of interest to those in the chemical community.

The Departments

Letters pp. 4-5

Newscripts p. 56

Glitches In Time, Navel Residents.

C&EN Archives

C&EN Archives

Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.

Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives

Environmental SCENE News

Fertilizer May Help Bacteria Slip Into Groundwater

Water Safety: High phosphate levels allow deadly microbes to pass through soil.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Sunlight Is An Effective Disinfectant

Public Health: Field work shows that a cheap water treatment method improves children's health.

House Takes Aim At Clean Air Act

Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.

Analytical SCENE News

New Method Isolates Membrane Proteins

Protein Purification: Technique separates proteins on a lipid bilayer.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Mapping Drugs In Human Tissue

Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.

Skeletons Come To Light

Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.

Analyzing Nuclear Processes

ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.

JACS Research In C&EN

Indole Changeup Yields Elusive Alkaloid

ACS Meeting News: Cyclization and nitrene insertion star in synthesis.

Prefab Synthesis Moves Ahead

Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.

Multiple Bradykinin States Revealed

The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.

Scaling Up The Axinellamines

A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.

A Revamped Vancomycin

Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.

CENtral Science

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


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