Global Top 50

Quote of the Week
"Sometimes it's the wacky science that you most don't want to miss supporting."
FRANCIS S. COLLINS, DIRECTOR, NATIONAL INSTITTUTES OF HEALTH – p. 32
July 25, 2011
In This Issue:
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Highlights

Cover Story
Global Top 50
Chemical producers show surprisingly good profits soon after the recession. (pp. 12-15)

Science & Technology
Biomarkers Wanted
Discovery of potential diagnostic tools has been plagued with problems. (pp. 40-43)

Career & Employment
Expats In China
International assignments are returning, but with far fewer perks. (pp. 49-50)
Table of Contents
News Of The Week
One Home For Various Guests p. 7
Supramolecular Chemistry: Chemical cage captures a variety of compounds, regardless of charge.
Taking Home The Gold p. 8
Academics: U.S. high school students earn two gold and two silver medals at International Chemistry Olympiad.
Ecolab To Buy Water Firm Nalco p. 8
Specialties: Transaction will create a leader in water treatment and cleaning products.
A Personal Meter For Everything p. 9
Sensors: System allows glucose monitors to measure other analytes.
Sweet Biopolymers Deal p. 9
Mitsui & Co., Dow Chemical joint venture in Brazil will be based on sugarcane.
Seattle Genetics Hits A Key Target p. 10
Pharmaceuticals: FDA panel gives thumbs up to antibody-drug conjugate.
The (Synthetic) Nose Knows p. 10
Bioelectronics: Chemical sensor combines olfactory proteins and carbon nanotubes to mimic biology.
Blueprint For Science Education p. 11
Curriculum: Framework is supposed to yield national teaching standards by 2012.
Slate Set For ACS Fall Ballot p. 11
Election: Candidates for president-elect, director-at-large, and district III and VI directors.
Business

Paying Attention To Manufacturing pp. 18-22 (Member Content)
Consortia aim to bridge the gap between drug development and manufacturing with a technology and engineering focus.
China Draws Catalyst Suppliers pp. 24-26 (Member Content)
Technology providers see opportunity as China seeks to make better plastics.
Business Concentrates pp. 16-17 (Member Content)
- CPChem’s Fate Unsure in ConocoPhillips Split
- ConocoPhillips' plan to divide into two independent companies has left undecided the fate of the firm's polypropylene business...
- SEC Looks Into Insider Trading
- At the request of the U.S. Securities & Exchange Commission, a judge has frozen the assets of three firms suspected of insider trading just before...
- Kissam To Be CEO At Albemarle
- Albemarle has named Luther C. Kissam as its next CEO, effective on Sept. 1...
- DuPont Sued Over New Herbicide
- A homeowner in Pennsylvania and a chain of golf courses in Indiana have filed a class-action lawsuit against DuPont claiming...
- Dow Sells Plants In Germany To H.I.G.
- The private equity firm H.I.G. Capital has purchased Haltermann Products from Dow Chemical...
- Huntsman Boosts Electrolyte Capacity
- Huntsman Corp. is increasing capacity for its Ultrapure electrolyte solvents in response to growth in the lithium-ion battery market...
- Catylix Licenses Fluorine Technology
- Catylix has licensed technology developed by University of Illinois, Urbana-Champaign...
- Ajinomoto Launches Indian Pharma Chemicals
- Ajinomoto OmniChem and Granules India have agreed to form a 50-50 contract manufacturing joint venture...
- Pfizer Buys Icagen In Pain Drug Deal
- Pfizer has agreed to pay $6.00 per share, or $50 million, for Research Triangle Park, N.C...
- Roche Buys Oncology Diagnostics Firm
- Roche has agreed to acquire MTM Laboratories, a privately held German firm that develops in vitro diagnostics...
- LEO Pharma, Scripps Target Skin Disease
- After deciding to increase its focus on dermatology, LEO Pharma has set up a collaboration with Scripps Research Institute...
- Altana Unit Opens New Jersey Lab
- The Actega unit of the German specialty chemicals maker Altana has opened a laboratory in Cinnaminson, N.J....
- Allergan And Valeant Expand In Dermatology
- Three dermatology businesses have changed hands in recent weeks. Allergan is paying $75 million up front and...
- Business Roundup
- Ashland, Showa Denko, Thermo Fisher Scientific, DuPont, Impax Pharmaceuticals, Synthos, AMAG Pharmaceuticals, Ascletis, Lonza...
Career & Employment

Expats In China pp. 49-50
International assignments are returning, but with far fewer perks.
This Week Online

Meals Modify Proteins
Proteomics: Levels of protein acetylation may change in response to feasting or fasting.
How To Become A Video Star
C&EN's YouTube channel is collecting videos from chemists around the world. Contributing Editor Aaron Rowe explains the easy steps behind an effective video.
A Tragedy And Synthetic Marijuana
C&EN blogger David Kroll explains the origins of synthetic marijuana products, their intense psychoactive effects, and how governments are trying to regulate them.
Government & Policy

Preventing Disaster pp. 30-32 (Member Content)
Chemical industry seeks regulatory certainty in antiterrorism standards.
Aiding Innovation In Tough Fiscal Times pp. 34-35 (Member Content)
Experts warn that scientific creativity in the U.S. will decline without adequate funding.
Insights: Bidding Adieu To The Shuttle p. 36 (Member Content)
Program ends after 30 years, leaving a mixed legacy.
Government & Policy Concentrates p. 28 (Member Content)
- House Passes Energy-Water Appropriations Bill
- The U.S. House of Representatives passed the fiscal 2012 energy-water appropriations bill on July 15...
- Manufacturers Oppose Tighter Ozone Standard
- The American Chemistry Council and the American Petroleum Institute are among large industry groups that are calling for...
- National E-Waste Strategy Unveiled
- Representatives from industry and the Obama Administration last week announced a strategy for the responsible design, purchase, management, and recycling of ...
- NIST Posts New Values For Constants
- The National Institute of Standards & Technology is posting the latest internationally recommended values for the fundamental constants of nature...
- Senate Bill To Delay Boiler Rules
- EPA would have 15 months to repropose and finalize rules governing hazardous industrial-boiler emissions under a draft bill introduced in the Senate last week...
» more government & policy news...
ACS Comment
Meeting The Challenges Of National Meetings p. 46 (Member Content)
ACS News

IYC Profile: Ghana p. 47
David Dodoo studies the environmental impact of mining on this West African nation.

Social Networking And C&EN
You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.
Science & Technology

Biomarkers Wanted pp. 40-43
Discovery of potential diagnostic tools has been plagued with problems.
More Than Just Cancer: Some Biomarkers Move Toward Validation p. 43
Fishing For Biomarkers Web Exclusive
Why Water Fills Nanotubes p. 44 (Member Content)
Researchers probe origin of puzzling phenomenon and discover emptying, too.
Science & Technology Concentrates pp. 38-39
- A More Stable Silyl Ether
- Making more robust silyl ethers just got easier, thanks to a protecting group developed by Harvard University
- Making Better Sodium-Ion Batteries
- The performance of sodium-ion batteries can be markedly improved by substituting common carbon-based anode materials
- Getting FlaK
- The first X-ray structure of a membrane aspartyl protease helps explain how the enzyme does its difficult job
- Electrical DNA Sequencing Unveiled
- A light-free DNA sequencing method harnesses the same semiconductor manufacturing technology used to make computer chips
- Isotope Effects On Acidity Resolved
- The answer to a 50-year-old question about the origin of secondary isotope effects on acidity could lead to new insights on molecular structure and reactivity
- Computing A Four-Atom Reaction
- Pushing the envelope of what can be calculated by using the Schrödinger equation
- Grubbs Ruthenium Catalysts Explained
- In a bid to solve a long-standing chemical mystery and to help improve catalyst design
- Improving Polymer Tandem Solar Cells
- Blending gold nanoparticles into the layer connecting the two subcells of a polymer tandem solar cell boosts the device’s performance
» more science & technology news...
Meetings
2011 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community.
The Departments
Letters pp. 4-5

Newscripts p. 56
Glitches In Time, Navel Residents.
C&EN Archives

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Environmental SCENE News
Fertilizer May Help Bacteria Slip Into Groundwater
Water Safety: High phosphate levels allow deadly microbes to pass through soil.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Sunlight Is An Effective Disinfectant
Public Health: Field work shows that a cheap water treatment method improves children's health.
House Takes Aim At Clean Air Act
Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.
Analytical SCENE News
New Method Isolates Membrane Proteins
Protein Purification: Technique separates proteins on a lipid bilayer.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Mapping Drugs In Human Tissue
Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.
Skeletons Come To Light
Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.
Analyzing Nuclear Processes
ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.
JACS Research In C&EN
Indole Changeup Yields Elusive Alkaloid
ACS Meeting News: Cyclization and nitrene insertion star in synthesis.
Prefab Synthesis Moves Ahead
Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.
Multiple Bradykinin States Revealed
The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.
Scaling Up The Axinellamines
A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.
A Revamped Vancomycin
Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.
CENtral Science
» News, notes, and musings from C&EN
Check out some of the recent posts from C&EN's blog, "C&ENtral Science"
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