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May 20, 2002
Volume 80, Number 20
CENEAR 80 20 pp. 32-36
ISSN 0009-2347


PNNL RESEARCH
Biodetection Enabling Analyte Delivery System

The Biodetection Enabling Analyte Delivery System (BEADS) is an automated front-end sample preparation device for pathogen detection. The system literally uses a packed bed of beads--tiny glass, polymer, or magnetic spheres--to capture chemical or biological species of interest. BEADS works for liquid, gas, or solid contaminants by suspending them in liquids and placing them in contact with the beads, says Jay W. Grate, PNNL senior chief scientist. The beads are automatically delivered and released for each sample. Bacteria, spores, viruses, or their DNA bind to the beads while other material is washed away. The system concentrates and purifies the protein or DNA from environmental samples for biodetection. BEADS has many applications, such as monitoring air and water contamination and for detecting food contamination or the presence of biowarfare agents.

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PHOTO BY JEFF JOHNSON

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Chemical & Engineering News
Copyright © 2002 American Chemical Society



 
Cover Story
CELLULAR FUTURE
Creative chemistry, biology, plus powerful instruments and computers propel Pacific Northwest National Laboratory into proteomics era

MISSION
Chemistry And Biosciences Are Priorities At PNNL

CLEANUP
The Hanford Connection

PNNL RESEARCH
Biodetection Enabling Analyte Delivery System

PNNL RESEARCH
Solid Oxide Fuel Cells

PNNL RESEARCH
Spiders, Fireflies, And Microbes

PNNL RESEARCH
The Virtual Lung

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