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March 1, 2010 - Volume 88, Number 9
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October 24, 2011
Celanese Takes An Ethanol Plunge (Member Content)
(October 24, 2011 | Vol. 89 Issue 43 | pp. 20-21)The chemical producer seeks to make ethanol a major business but is secretive about details of its process.
Building On The Momentum (Member Content)
(October 24, 2011 | Vol. 89 Issue 43 | p. 22)BWA Water Additives rides crest of rising demand for specialty water treatment chemicals.
European Firms Invest In China
(October 24, 2011 | Vol. 89 Issue 43 | p. 6)Specialty Chemicals: Companies pursue local research and production.
Investors Bet On Cleantech
(October 24, 2011 | Vol. 89 Issue 43 | p. 9)Green Chemistry: Close to $1 billion is slated for start-up firms.
Business Concentrates (Member Content)
(October 24, 2011 | Vol. 89 Issue 43 | p. 18)
October 17, 2011
Emerging Strategies
(October 17, 2011 | Vol. 89 Issue 42 | pp. 15-26)Faced with change, pharmaceutical firms shift business mix to generics and emerging markets.
A Sense of Urgency (Member Content)
(October 17, 2011 | Vol. 89 Issue 42 | pp. 30-32)Call for drug safety pushes the mundane art of supply chain management to the front burner.
Growing Businesses The Scottish Way (Member Content)
(October 17, 2011 | Vol. 89 Issue 42 | pp. 33-35)Development authorities seek to harness industry‑academia cooperation in the life sciences.
An Update On Dow (Member Content)
(October 17, 2011 | Vol. 89 Issue 42 | pp. 36-38)CEO Andrew N. Liveris believes the major pieces are in place to continue the company's transformation.
AstraZeneca Shifts Operations
(October 17, 2011 | Vol. 89 Issue 42 | p. 10)Pharmaceuticals: Firm will add manufacturing in China while cutting jobs in the U.S.
Investment Deterrent
(October 17, 2011 | Vol. 89 Issue 42 | p. 11)Venture capital firms say FDA regulations hamper their support of biopharma companies.
Business Concentrates (Member Content)
(October 17, 2011 | Vol. 89 Issue 42 | pp. 28-30)
When the French beauty giant L'Oréal considers launching a new product, it has always sought to fulfill characteristics such as safety, innovation, and performance. In recent years, that list has been expanded to include sustainability. Pictures of a preening frog around L'Oréal's ecotoxicity lab have a caption that illustrate the goal: "On peut être vert et beau," or, "We can be green and beautiful."
The effort around sustainability coincides with growing pressure from European regulators to provide clear information on how raw materials affect the environment. The Registration, Evaluation, Authorization & Restriction of Chemical substances (REACH) program, initiated in Europe in 2006, requires companies to provide toxicology data on thousands of chemicals. For cosmetics makers such as L'Oréal, that has meant retrospectively testing ingredients and products in development to ensure that they are safe to consumers and that they don't stick around in the environment once they are used.
When assessing the environmental impact of a raw material, L'Oréal looks at five characteristics, says Marc Leonard, who is in charge of ecotoxicity testing at the company's R&D facility in Aulnay, France. As always, consumer safety is paramount. But the company also looks at an ingredient's impact on the environment, how harvesting could impact biodiversity, fair trade in natural ingredients sourcing, and the social impact of sourcing an ingredient from an indigenous population.
"From a regulatory standpoint, 100% of raw materials go back into the environment after they are used by a customer," Leonard says.
To truly understand where a sunscreen, for example, ends up, L'Oréal scientists must consider the circuitous route it takes from store shelves to the nearby ecosystem. They then must assess whether small levels of an ingredient can disrupt the sophisticated microbial systems in sewage treatment facilities or whether a swimmer wearing a new sunscreen can contaminate a lake.
Algae are the most sensitive components of an aquatic environment, so L'Oréal begins by testing the impact of a new ingredient or formulation on them. The process is more complicated than it sounds. Because many substances used in cosmetics contain ingredients that interfere with light, biomass can't be measured with fluorescence, the most straightforward tool. Instead, a researcher has to count algae under a microscope to determine whether they are losing numbers after being exposed to a product.
If an ingredient passes muster in algae, it then is used in more complex systems: first daphnid, known more commonly as the water flea, then zebrafish.
Ecotoxicity is critical for L'Oréal, but it is not always understood by consumers. A growing number of consumers are demanding that their personal care products be biodegradable. This is an admirable quality, but as Leonard points out, an ingredient that biodegrades is not guaranteed to be safe. "We don't care if a product doesn't degrade in one month if it kills everybody in a river in two days," Leonard points out.
L'Oréal has assessed more than 97% of its own raw materials, Leonard says, and the company is now looking at those it sources from other suppliers.
As another way of softening its impact on Earth, L'Oréal is trying to make its manufacturing processes more efficient, says Michel D. Philippe, green chemistry manager at the Aulnay site. When considering a new raw material, either discovered in its labs or sourced externally, the company measures its "E factor"—the waste generated per kilogram produced. If the number comes up too high, L'Oréal tries to come up with an alternative synthesis to lessen the environmental impact.
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- Copyright © 2011 American Chemical Society
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