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July 12, 2010
Volume 88, Number 28
p. 4

July 12, 2010 Letters

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Chemical Safety: Dangers Of Diglyme

Reading the investigators’ account of the T2 Laboratories explosion, which was attributed to metallic sodium and hot di­glyme, we suspect this may be an example of a much wider phenomenon, already met in other guises (C&EN, Sept. 21, 2009, page 8). A previous account of a violent runaway in diglyme, postulated as powered by reaction with finely divided active metal (in this case aluminum) has long been in “Bretherick’s Handbook of Reactive Chemical Hazards,” but, having its primary entry under “lithium aluminium hydride,” might be missed by the hasty searcher.

We are also strongly reminded of the Seveso, Italy, accident of 1976 (and its several precursors). Investigation showed that these were the result of a high-temperature, base-induced decomposition of diethylene glycol, or ethylene glycol itself, to materials including hydrogen and water, the coreagent sodium hydroxide, not sodium metal, and the temperature again around 200 °C.

Thermodynamic calculations from “Heats of Formation” suggest that 1,2 diols are higher energy than they look and may dehydrate exothermically. This, no doubt, is why biology finds sugars so useful as fuels and energy stores (and why sugar refineries occasionally have explosions from a hot molasses decomposition usually attributed to Maillard reaction with protein impurities).

Capping the glycol as an ether, so that methanol, or dimethyl ether, is eliminated rather than water, will do little to the thermodynamics—and perhaps not much to the kinetics—of reaction. The simplest diethyleneglycol ether, dioxan, is known to decompose exothermically at around 200 °C.

Martin J. Pitt
Assistant Editor, Bretherick’s Handbook
Chemical & Process Engineering, University of Sheffield
Sheffield, U.K.
Peter G. Urben
Editor, Bretherick’s Handbook
Kenilworth, U.K.

Chemical & Engineering News
ISSN 0009-2347
Copyright © 2011 American Chemical Society
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