-
May 23, 2011 - Volume 89, Number 21
- p. 33
Science & Technology Concentrates
More Science & Technology Concentrates
- Safer Synthesis Of Fluorophosphate Crystals
- Method for making analogs of metal oxides avoids hydrofluoric acid
- Biomass Burning Generates Isocyanic Acid
- Mass spectrometry method detects part-per-trillion levels of inflammation agent
- C-C Protein Crosslink Creates Substrate Pocket
- Novel structure found in microscopic algae protein
- Weak Acids Irritate Ion Channel
- Mechanism identifies action of acetic acid on cell membrane
- Metathesis Catalyst Catches A Few More Zs
- Revised version of ruthenium catalyst improves selectivity for Z alkenes in olefin metathesis reactions
- Spotting Clotting
- Detection strategy for blood clot regulator combines oligonucleotide, fluorescent probe and reversible inhibitor
- Molecules Vanish In Nanotubes
- Molecular dipoles induce mirror-image nanotube dipole that screen molecules from IR light
- Natural Halocarbon In Boar Meat
- Fungi chemical could aid understanding of halogenated pollutants
Topics Covered
More Science Stories
October 24, 2011
Bryostatins Retain Promise
(October 24, 2011 | Vol. 89 Issue 43 | pp. 10-17)New results in total synthesis reinvigorate a 40-year-old field of research.
For Cave's Art, An Uncertain Future
(October 24, 2011 | Vol. 89 Issue 43 | pp. 38-40)Disagreement on conservation course of action complicates a potential reopening.
Cancer Stem Cells
(October 24, 2011 | Vol. 89 Issue 43 | pp. 41-43)Researchers zero in on the pathways that allow cancer to bounce back after treatment.
What's That Stuff? Blue Jeans
(October 24, 2011 | Vol. 89 Issue 43 | p. 44)Making the iconic pants requires both color-addition and color-removal chemistry.
Shedding Nanoparticles
(October 24, 2011 | Vol. 89 Issue 43 | p. 5)Materials Science: Chemists observe metal objects sloughing off ions to form nanoparticles.
Modifying Messenger RNA
(October 24, 2011 | Vol. 89 Issue 43 | p. 7)Chemical Biology: Methylated bases in mRNA may have roles in gene regulation and obesity.
Lab-On-A-Chip For Planets, Moons
(October 24, 2011 | Vol. 89 Issue 43 | p. 8)Microfluidics: Automated chip is designed to detect extraterrestrial amino acids.
New Editor For Analytical Chemistry
(October 24, 2011 | Vol. 89 Issue 43 | p. 9)Publishing: Jonathan Sweedler to take the helm.
Science & Technology Concentrates
(October 24, 2011 | Vol. 89 Issue 43 | p. 37)
October 17, 2011
Improving Shop Safety
(October 17, 2011 | Vol. 89 Issue 42 | pp. 56-57)Yale updates policies on machine shop use after student death.
Cleaning Acrylics
(October 17, 2011 | Vol. 89 Issue 42 | pp. 58-59)Conservation scientists seek new ways to keep modern paintings looking their best.
Detecting H2S In Vivo (Member Content)
(October 17, 2011 | Vol. 89 Issue 42 | p. 60)Studies could lead to sensitive and selective analyses for tiny signaling agent.
Rules For Design
(October 17, 2011 | Vol. 89 Issue 42 | p. 9)Materials Science: Guidelines predict structures formed by nanoparticles and DNA linkers.
Identifying Modified Cells
(October 17, 2011 | Vol. 89 Issue 42 | p. 11)Molecular Biology: Technique tags and enriches cells genetically altered by nucleases.
Linker-Free Molecular Wires
(October 17, 2011 | Vol. 89 Issue 42 | p. 12)Electronics: Metal-carbon bonds increase electrical conductance.
Asymmetry From A Guest
(October 17, 2011 | Vol. 89 Issue 42 | p. 13)Stereochemistry: Enzymelike pocket that hosts chiral species controls catalyst's enantioselectivity.
Science & Technology Concentrates
(October 17, 2011 | Vol. 89 Issue 42 | pp. 54-56)
Angew. Chem. Int. Ed.
A DNA aptamer (black) tightly binds thrombin (green) while a reversible inhibitor (pink) keeps natural inactivators away.
A three-molecule tag team could help physicians monitor a patient’s blood clotting during major surgeries such as hip replacements, scientists in Germany report (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201007032). Excessive bleeding and excessive clotting lead to complications during surgery, so monitoring clotting could save both costs and lives. An enzyme called thrombin sits at the nexus of the complex biochemical network that controls clotting, but so far no diagnostic tests that measure thrombin activity are available. A team led by Bernd Pötzsch of the University Clinic Bonn and Günter Mayer of the University of Bonn surmised that previous thrombin testing hasn’t panned out because naturally occurring thrombin inhibitors rapidly inactivate thrombin in blood samples. So they developed a strategy that begins by adding a reversible thrombin inhibitor to a blood sample, which keeps natural inhibitors out of the picture. After attaching the inhibitor-thrombin complex to a surface via a two-pronged DNA aptamer, the team washes away the reversible inhibitor and measures the captured thrombin’s activity with a fluorescent probe. With their technique, the Bonn team kept tabs on thrombin activity in five patients undergoing hip replacements.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © 2011 American Chemical Society
Services & Tools
ACS Resources
ACS Careers
ACS is the leading employment source for recruiting scientific professionals. ACS Careers and C&EN Classifieds provide employers direct access to scientific talent both in print and online. Jobseekers | Employers
» Join ACS
Join more than 161,000 professionals in the chemical sciences world-wide, as a member of the American Chemical Society.
» Join Now!
Popular Sections
ACS, Analytical SCENE, Business, Careers, Economy, Editor, Education, Employment, Environmental SCENE, Letters, Government, Photo Galleries, Policy, Movies, Multimedia, Nanotechnology, Newscripts, Reel Science, Safety Letters, Science, Stem Cells, Stimulus Funds, Technology, Vaccines, Videos, What's That Stuff
Advertisements
