Here are three of C&EN’s favorite structures of 2016. /articles/94/i49/Biological-structures-year.html 20161208 Nearsighted pictures portend farsighted applications 94 49 /magazine/94/09449.html /departments/.html Biological structures of the year Science & Technology Sarah Everts Surprisingly, a DNA enzyme, or DNAzyme, had never been visualized before this year because researchers had been unable to crystallize this type of catalyst. The feat comes thanks to a team led by Claudia Höbartner and Vladimir Pena of the Max Planck Institute for Biophysical Chemistry, who reported the structure of a DNAzyme called 9DB1, which specializes in stitching together RNA strands. The new structure could enable more rational design of single-stranded DNAzymes for biomedical use (Nature 2016, DOI: 10.1038/nature16471).
by Sarah Everts |
December 08, 2016