Acceptance both within the agency and by the public for the use of computational toxicology in EPA’s regulatory decisions is likely to grow as this science matures, the draft states. EPA’s integration of computational toxicology data into its regulatory work is apt to begin by supplementing, then probably replacing, existing methods such as experiments with lab animals, it adds. To ensure acceptance, scientists need to demonstrate that computational toxicology data are valuable in predicting a chemical’s hazard, showing that this information is sufficiently able to estimate toxicity in lab animals and, ultimately, in people. Only then will agency decisions relying only on computational toxicology data “be scientifically defensible within an acceptable level of uncertainty,” the draft says.
by Cheryl Hogue |
March 04, 2013