—NONSTEROIDAL CONTRACEPTIVE “Compound may have fewer side effects than current steroidal agents” FROM THE ACS MEETING Researchers disclosed for the first time at the ACS national meeting in Philadelphia the design, synthesis, and structure of Tanaproget, a nonsteroid that is now in clinical test ing as an oral contraceptive for women. All oral contraceptives in current use contain steroid-based progesterone receptor (PR) agonists. These agonists tend to interact with other receptors and pathways, leading to side effects that range from nausea, headaches, cramps, tenderness, and pain to mood changes and increased risk of cardiovascular complications.
by Stu Borman |
August 30, 2004