—DNA cytoskeleton strengthens liposomes “Three DNA sequences self-assemble to form an artificial cytoskeleton that shores up lipid membranes” Liposomes have many potential uses: as models for biological cells, as biosensor platforms, and as drug delivery systems. But these lipid membrane structures are fragile. To shore up these structures, Miho Yanagisawa of Tokyo University of Agriculture & Technology, Masahiro Takinoue of Tokyo Institute of Technology, and coworkers use DNA as a structural material to build a cytoskeleton for liposomes (Proc. Natl. Acad. Sci. USA 2017, DOI: 10.1073/pnas.1702208114). The researchers make the cytoskeleton out of three DNA sequences that self-assemble into a Y-shaped double-stranded motif with overhanging pieces of single-stranded DNA.
by Celia Henry Arnaud |
July 10, 2017