The small flow setup the team used could be dedicated to making this single compound and then discarded, if necessary, at no great cost, Cole said. The success of using flow to make prexasertib prompted Lilly to build a continuous-flow facility in Kinsale, Ireland, which opened in October. Flow chemistry was popular elsewhere this year. Flow chemistry company Snapdragon partnered with Pfizer to prepare the highly reactive reagent allenyllithium en route to making an important drug intermediate. Snapdragon also formed a pact with Johnson Matthey, a leading supplier of bulk pharmaceutical chemicals, to collaborate on flow chemistry for drug manufacturing. /articles/95/i49/Flow-chemistry-advanced-industry.html 20171213 Lilly chemists capitalized on continuous chemical manufacturing to make a chemotherapy drug candidate 95 49 /magazine/95/09549.html /departments/.html Flow chemistry advanced in industry Science & Technology Bethany Halford A walk-in fume hood contains newly designed continuous-flow equipment at Eli Lilly’s facility in Kinsale, Ireland.
by Bethany Halford |
December 13, 2017