—A Little Palladium Does A Lot Of Cross-Coupling “Green Catalysis: Iron nanoparticles containing traces of palladium facilitate workhorse reactions in a recyclable aqueous solution” As part of their efforts in developing greener chemistry, Bruce H. Lipshutz and his group at the University of California, Santa Barbara, have already pared Suzuki-Miyaura cross-coupling reactions down to no organic solvent, little if any heating, and a minimum of palladium catalyst. But the fact that their recyclable aqueous reaction system still requires a relatively expensive amount of scarce palladium has bothered Lipshutz. His group has now found a way to reduce the amount of palladium further. Working in collaboration with Novartis, the researchers discovered that some types of inexpensive, commercially available FeCl3 naturally contain parts-per-million amounts of the precious metal.
by Stephen K. Ritter |
September 07, 2015