—Light-sensitive gel forms 3-D cell matrix “Multiphoton lithography makes cell-compatible microenvironment from photosensitive hydrogel” Researchers have developed a photosensitive hydrogel that could aid the development of high-resolution 3-D cell microenvironments for engineering tissues, growing miniorgans, modeling diseases, and screening drug candidates. Scientists have made cell microenvironments primarily from two substances: collagen gels, which are natural protein-based systems that are not readily customizable, and polyethylene glycol, which is not photosensitive and therefore not tunable at subcellular resolution. Now, Xiao-Hua Qin of Empa, the Swiss Federal Laboratories for Materials Science & Technology, and coworkers have developed a high-resolution, light-induced technique for forming polyvinyl alcohol cell matrices (Adv.
by Stu Borman |
February 12, 2018