The comprehensive proteomic, transcriptomic, and metabolomic analysis of the pneumonia-causing bacterium sets a new standard for systems biologists seeking to understand the underpinnings of a biological cell. It also provides new information that could help design drugs against the pathogen. In three back-to-back Science papers (2009, 326, 1235, 1263, and 1268), scientists reveal that M. pneumoniae has “features of transcription controls and protein organization that are much more subtle and intricate than were previously considered possible in bacteria and, in many ways, appear similar to mechanisms in eukaryotes,” Howard Ochman and Rahul Raghavan of the University of Arizona, Tucson, write in an associated commentary.
by Sarah Everts |
November 30, 2009