Modern Drug Discovery Home Page

Table of Contents

January-February 1999
Volume 2, Number 1

FEATURES

	The price of a pill Finding the correct pricing stategy is a complex, high-stakes puzzle for drug companies. Even war games have been found helpful in deciding how much a new medicine should cost. Crispin Littlehales
	Russian jailhouse genomics: Enlisting a genome to fight MDR tuberculosis Jim Kling The genomic DNA sequence of Mycobacterium tuberculosis brings a new drug discovery tool to the fight against multiple drug resistant tuberculosis.
	Rational drug design: Controlling the size of the haystack Donald B. Boyd Combinatorial chemistry creates larger and larger haystacks in which to find the needle. Rational design attempts to focus the design process on the smallest possible set of viable compounds.
	Taming the monster haystack: The challenge of compound management Randy Wedin There's nothing glamorous about software that keeps track of library compounds. But whether you build it or buy it, it's essential for success with high-throughput technologies.
	E pluribus product Robert A. Lipper How can we optimize selection of drug development candidates from many compounds at the discovery stage?

DEPARTMENTS

	Editorial
	In Brief Tomato and potato steroids inhibit anesthetics metabolism Trichomoniasis opens door for HIV infection A once-every-three-months drug for multiple sclerosis Studying bone growth in space Using bacteria to put the brakes on cancer Government may fund human stem cell research To your health
	Analysis Getting past the politics and paperwork of pediatric drug studies
	Reviews The PHARM Game: Drug Discovery and Development Viruses, Plagues, and History
	New Products
	Meetings
	Ad Index
	EtCetera