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| Volume 7, Issue 4 | ||
| Table of Contents | ||
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| Article Indexes | |
| Author Indexes | |
| Product Info Now: April 2004 | Table of Contents | |
| Featured Product: | ||
| View more products below | ||
Solid reagent option for microwave flow reactor The Voyager Microwave Flow-Through Synthesis System offers options for handling solids, slurries, and highly viscous fluids. Two separate flow-through modules are designed to handle the entire range of scale-up applications. The Voyager CF (Continuous Flow) module is the choice for scaling up solution-based chemistries, while the Voyager SF (Stop Flow) module (pictured above) is the option for scaling up chemistries with solid reagents, highly viscous materials, or insoluble products. Both modules allow the automated scale-up of chemistries with microwave energy, all with a completely safe, self-monitored platform. The SF option allows for the synthesis of up to 50 mL of material automatically, giving chemists all of the safety advantages of the Voyager flow-through design while yielding the productivity and solids compatibility found with static batch systems. As part of the Discover family of microwave synthesis products, Voyager can handle single, small-scale reactions as well as scale-up to kilogram quantities. The system also can perform atmospheric and pressurized reactions, and it has temperature and pressure feedback control. The use of active flow cells allows the user to suspend reagent beds in the flow stream. These solid reagent beds can consist of immobilized reagents, catalysts, scavengers, or coupling enhancers. Active flow cells can be prepared by the user to allow maximum versatility in the process. CEM Corp. - www.cem.com |
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| More Products | ||
Cells. Supercharge EZ10
Electro competent Cells offer the highest available transformation efficiency,
1010 transformants/µg pUC19. The high transformation efficiency
is especially useful for large constructs such as adenoviral vectors. Electroporation
of constructs into these cells provides better stability. The cells are supplied
prealiquotted, preserving transformation efficiency and viability because there
is no need to refreeze and thaw them. Each tube contains 80 µL, enough to
perform two transformations. Chromatography guide. The 48-page Effective
Organic Compound Purification handbook is a comprehensive resource of purification
guidelines and tactics for organic chemists using flash chromatography. This first
edition provides valuable reference information as well as a variety of detailed
illustrations, a handy Column Selection Guide, reference information on solvent
characteristics, and a Troubleshooting Guide for LC Systems. Label printers. The H-426 and H-434 series
of all-metal thermal transfer printers are available in 203 or 300 dpi. Suited
for high-volume printing, these models feature a full backlit LCD and standard
real-time clock. Serial, parallel, PS/2, and USB interfaces are standard. The
H-series’ internal memory, which is used for storing downloaded label formats,
graphics, and fonts, allows the printers to be operated without being connected
to a computer. Resequencing system. The VariantSEQr Resequencing
System is a complete solution for the discovery of DNA variants that includes
high-confidence, ready-to-use primers for thousands of genes in the human genome.
The system enables researchers to conduct sequence variation studies, such as
correlating genotypes with biological function or response to treatment, cost-effectively
and in a manner not previously possible. Labeling program. LabelMark V3 software
lets users design and print vial, tube, slide, and well-plate labeling. The software
makes it possible to create date- and time-stamped, vial top and wraparound labels.
Simple to advanced serialization can be easily done, making aliquotting a simple
process. The program even includes graphic elements for commonly used laboratory
symbols and a custom template for laboratory applications. Features include simplified
importing of data, redesigned toolbars and menus, and a “find and replace”
utility. Bottle-top filter unit. The Stericap PLUS
is a vacuum-driven device that rapidly sterilizes up to 10 L of tissue culture
media, microbiological media, buffers, and other biological solutions. The unit
features a low-protein-binding poly(ether sulfone) (PES) membrane that provides
both rapid flow rates and high throughput. Its proprietary hydrophilic surface
ensures sterilizing-grade retention of bacteria and other potential contaminants.
The Stericap PLUS unit comes presterilized and requires no setup or cleanup. A
built-in air vent prevents air locking during filtration. ELISA system. The Mouse GITR/TNFRSF18 DuoSet
ELISA Development System features glucocorticoid-induced tumor necrosis factor
receptor (GITR), also known as activation-inducible tumor necrosis factor receptor
(AITR), a type I transmembrane receptor and member of the TNF superfamily designated
TNFRSF18. Mouse GITR is expressed in normal T cells from thymus, spleen, and lymph
nodes and is not expressed in nonlymphoid tissues. The only known ligand for GITR
is GITR Ligand/ TNFRSF18, also known as AITR Ligand and TL6. Diaphragm pumps. T Squared Compact High-Performance
Diaphragm Pumps offer compact, reliable solutions for portable and self-contained
air/gas OEM applications. The T Squared family begins with the T2-01 and T2-02,
which feature flow capabilities up to 35 and 13 SLPM, respectively. T Squared
T2-03 and T2-04 address 2.5–5 SLPM flow requirements in which performance,
pump life, and cost are critical yet compact size is key. T Squared pumps are
proven performers in NIBP, pathogen detection, and gas analyzer OEM applications. Workstation. The Biomek 3000 Laboratory
Automation Workstation is designed for systems biology-focused genomic, proteomic,
and cell-based research. This flexible platform fits in standard laminar flow
hoods for applications requiring a controlled environment. The Biomek 3000 features
interchangeable tools for a wide variety of functions, including gripper single-
and eight-channel pipetting tools. The system’s multichannel tools are designed
with true 9-mm center-to-center tip spacing, allowing the use of ANSI/SBS standard
tip racks. Gel purification. Available for unmodified
oligonucleotides of all lengths up to 150 bases, the MWG-HYPUR gel purification
system combines nontoxic hydrogel electrophoresis with a revolutionary elution
technology, resulting in higher yields and better quality than polyacrylamide
gel electrophoresis (PAGE). Other advantages are faster turnaround time, quality
control by MALDI TOF MS analysis for all oligos up to 120-mer, and gel slice excision
in blue light. Assay platform. HALO is a rapid, high-throughput,
multifunctional hemotoxicity testing system that can be used at all stages of
drug development, from screening to clinical trials. Based on the classical semisolid
colony-forming procedure, the system is a proliferation assay with nonsubjective
luminescence readout. HALO is a standardized assay performed in 96-well plates.
The HALO Kit Platform detects and measures at least 14 different hematopoietic
populations either individually or in combination for 5 different species. The
kits are available in different sizes for maximum flexibility to perform any in
vitro hematopoietic/hemotoxicity testing. Workstation. The Eppendorf epMotion 5070
liquid-handling workstation enables rapid and reproducible liquid handling through
automated pipetting, dispensing, and dispensing variants. Pipetting sequences
and protocols previously performed manually can be transferred to the epMotion
5070, which is controlled via the mouse and keyboard of the integrated control
panel instead of a PC. An optical sensor system controls and ensures the reliability
of the procedure. RNA isolation. With tissue samples for
genomic analysis often small and irreplaceable, an RNA isolation service helps
ensure maximum RNA recovery and high-quality gene expression data. GenUs BioSystems’
bioarray service laboratory offers researchers an alternative to performing this
delicate step in the gene expression profiling process in their own laboratory.
Established and proven RNA isolation methods take small amounts of cell and tissue
samples and generate gene expression data on which researchers can draw sound
conclusions. Chromatography medium. For optimized purification
of His-tagged proteins, the Ni Sepharose High Performance affinity chromatography
medium provides better protein binding capacity, negligible Ni leakage, and compatibility
with a wide range of reducing agents, detergents, denaturants, and other additives.
Its 34-µm bead matrix offers the highest binding capacity available to provide
more-concentrated samples, higher efficiency, time savings, and increased yield. Screening system. The LabChip 3000 Drug
Discovery System performs unattended biochemical and cell-based screening assays
using Caliper’s microfluidic chips. The company notes that this addition
to its suite of LabChip microfluidic systems is the first major product introduction
since Zymark Corp. and Caliper Technologies combined to create Caliper Life Sciences.
The LabChip 3000 system is an updated, much smaller, more affordable version of
the Caliper 250 system. Plasma analysis. The Plasma Metanephrine
Analysis Kit extracts free metanephrine (MN) and normetanephrine (NMN) from plasma
for HPLC–electrochemical detection analysis of the catecholamines’ metabolites.
The kit offers more direct correlation of plasma free metanephrine concentration
to the catecholamine and metanephrine production of adrenomedullary and pheochromocytoma
cells than other sources. Its method detects all but the smallest of pheochromocytomas,
yielding fewer false positive results than traditional biochemical tests. High-throughput synthesis. The Navigator
Automated Microwave Compound Factory brings the full potential of microwave synthesis
to a high-throughput application. Designed with open-architecture hardware and
software, Navigator can grow and adapt to the user’s needs. The system is
available with an integrated weighing station, automatic liquid and/or solid reagent
addition stations, purification capabilities, and separation accessories, as well
as deconvolution capabilities and a capping station. Navigator is configured with
96-position racks and an XYZ robotic arm that can act independently of the microwave
synthesis program. Antigen system. The Human CD58/LFA-3 system
features CD58, also known as lymphocyte function-associated antigen (LFA-3), a
cell-bound immunoglobulin superfamily receptor with only one known ligand, CD2.
CD58 is widely expressed on human hematopoietic and nonhematopoietic tissues,
leukocytes, eryth ro cytes, endothelial and epithelial cells, and fibroblasts.
As a receptor–ligand pair, the engagement of CD58 with CD2 optimizes immune
recognition and initiates T-cell expansion and activation. HPLC mobile phases. CHEM+ NECT packaging
technology provides a disposable, closed-system alternative to the traditional
and potentially hazardous preparation of HPLC mobile phases. These premixed mobile
phases are manufactured to customer specifications using reagent-grade components
to ensure equivalent performance, and they can be easily connected to any HPLC
system. CHEM+NECT solutions are also offered with stability data to validate long-term
consistency. Particle size analyzers. The Insitec is
the only fully compliant on-line analyzer that makes use of industry-standard
laser diffraction particle size analysis. It is therefore uniquely placed to serve
the process analytical technology needs of pharmaceutical milling, micronization,
spray drying, compaction, and granulation manufacturers looking to tighten quality
control, minimize off-specification material, and gain greater insight into individual
processes. Pipette tips. ART (aerosol-resistant tip)
pipette tips contain a patented barrier, are scientifically proven to eliminate
carryover contamination, and are suitable for PCR procedures and handling radioactive
and highly infectious samples. The barrier material is nonwicking, self-sealing,
hydrophobic HDPE that effectively blocks all liquid and aerosol passage. In addition,
the tips are certified to be RNase- and DNase-free by independent laboratories. Reagents. Brilliant SYBR Green-based QRT-PCR
reagents provide a universal solution to real-time PCR detection and gene quantification.
The SYBR Green dye binds specifically to double-stranded PCR products without
the need for sequence-specific probes. The QRT-PCR reagents are optimized on Stratagene’s
Mx4000 multiplex quantitative PCR system and Mx3000 real-time PCR system, and
are validated on most other QPCR instruments. |
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