TABLE OF CONTENTS
December 7, 1998
Volume 76, Number 49
CENEAR 76 49 1-80
ISSN 0009-2347

Quote of the Week

"Let's adopt another mind-set: There are methods that work and methods that don't. . . . Let's replace the uncertainty of anecdote with the power of clinical trials." Harold Varmus, NIH director page 14

NEWS OF THE WEEK

ROAD TO MERGER:   10
Joint venture is first step toward merger of Hoechst, Rhône-Poulenc.

REALLY BIG MERGER:   10
Exxon and Mobil will form world's largest company.

YET ANOTHER MERGER:   11
Viag, Alusuisse Lonza join forces, chemical businesses.

ONE LAST MERGER:   12
Total and Petrofina merge, chemical business worth some $8 billion.

TERROR ATTACK:   12
Institute of Medicine committee offers 61-point plan for responding to civilian chemical/biological threats.

DEACTIVATING NICOTINE:   13
European epilepsy drug blocks nicotine's addictive pathway in animals.

BREAST IMPLANTS:   13
No connection between silicone implants and certain diseases, science panel tells judge.

NEWS FOCUS

ALTERNATIVE MEDICINE:   14
Upgrading NIH's Office of Alternative Medicine means greater focus on clinical trials.

BUSINESS

BUSINESS CONCENTRATES:  23

SINGLE-SITE CATALYSTS:   25
Specialty chemical producers bring their technical strengths to a lucrative market.

BIOMASS ETHANOL:   29
New wave of companies takes on the challenges of commercial production of alternative fuel.

BUSINESS INSIGHTS:   33
Where's the science in environmental groups' campaign to ban soft vinyl toys?

GOVERNMENT

GOVERNMENT CONCENTRATES:  35

PLANNING FOR DISASTER:   36
Chemical industry is gearing up to meet requirements for risk management plans.

SCIENCE/TECHNOLOGY

SCIENCE/TECHNOLOGY CONCENTRATES:  39

COVER STORY

SELF-REPLICATION:   40
New experiments with peptide and nucleic acid chemistry may help to decipher molecular origins.

CARBENES AND NITRENES:   45
Character of elusive conjugated biradical intermediates is in hand at long last.

BOOKS

"THE BALTIMORE CASE":   47
Convergence of "minor" errors, personality conflicts, and politics that fueled infamous story are recounted.

ACS NEWS

NATIONAL CHEMISTRY WEEK:   50
All 188 ACS local sections participated in 11th annual event.

THE DEPARTMENTS

EDITOR'S PAGE

LETTERS

59 MEETINGS

80 NEWSCRIPTS


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Copyright © 1998 American Chemical Society