TABLE OF CONTENTS
TABLE OF CONTENTS
December 21, 1998
Volume 76, Number 51
CENEAR 76 51 1-56
ISSN 0009-2347

Quote of the Week

"Most people recognize now that the submarine volcanic environment, which we don't understand very well, is a potential site on any planet for life to evolve." John R. Delaney, University of Washington page 35

NEWS OF THE WEEK

SHELL REVAMPS:  6
Company to sell 40% of chemical operations, cutting back to core businesses.

DISAPPEARING LINK:  7
Solid-phase reaction products cleaved cleanly from support media.

BOVINE GROWTH HORMONE:  7
Monsanto has sold 100 million doses of its bioengineered product, but consumer groups ask FDA to halt its sale.

STEREOCHEMISTRY:  8
Contributions of single atoms, groups of atoms to molecules' chirality are mapped.

NUCLEAR CLEANUP:  8
DOE will shell out $6.25 million so its critics can monitor its efforts.

OUTSOURCING R&D:  9
Hoechst contracts out its U.S. drug development work to Quintiles Transnational.

BUSINESS

BUSINESS CONCENTRATES:  11

CAPITAL SPENDING:  13
C&EN poll of chemical firms finds spending on new plants and equipment projected to drop in 1999.

FINE CHEMICALS:  17
Pharmaceutical ingredients producers highlighted new products, capacity at annual exhibition.

POLYCARBONATES:  20
Producers are adding capacity to meet forecast rise in global demand.

COOLING WATER:  21
Two companies find ways around persistent treatment problem.

GOVERNMENT

GOVERNMENT CONCENTRATES:  23

DATA LAW:  24
Provision in federal appropriations bill may change availability of experimental data.

GOVERNMENT INSIGHTS:  26
Too many studies manipulate data to support an agenda.

ENVIRONMENT

OZONE LAYER:  27
Meeting on Montreal protocol takes further steps toward phaseout of ozone-depleting substances.

INTERNATIONAL

EU RESEARCH:  29
European Union launches 5th Framework Program for funding science and technology research.

SCIENCE/TECHNOLOGY

SCIENCE/TECHNOLOGY CONCENTRATES:  33

COVER STORY

HYDROTHERMAL VENTS:  35
Geochemists probing the ocean subfloor find dynamic chemistry and hints of microorganisms at work.

UNUSUAL CLUSTER:  40
Hydrogenase crystal structure may aid design of industrially useful catalysts.

STUDENT JOURNAL:  41
National Journal of Young Investigators, in electronic format, gets undergraduates involved.

THE DEPARTMENTS

LETTERS

EDITOR'S PAGE

42 SOFTWARE/DATABASE UPDATE

44 ACS NEWS

55 AWARDS

56 NEWSCRIPTS


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