TABLE OF CONTENTS
February 14, 2000
Volume 78, Number 7
CENEAR 78 7 p. 3
ISSN 0009-2347

NEWS OF THE WEEK

FEDERAL R&D BUDGET:   17
Administration seeks 3 increase overall in fiscal 2001, 7 more for basic research.

PFIZER TAKES THE PRIZE:   18
Hostile takeover bid of $90 billion secures Warner-Lambert.

PETROCHEMICALS DEAL:   18
Phillips and Chevron combine their chemicals businesses in a $6 billion, 50-50 venture.

ULTRA-COLD MAGIC:   19
Preparation of nearly motionless Rb2 dimers may point way to molecular lasers.

ACRYLIC ACID:   19
Three new joint ventures set for production of fast-growing monomer.

DEFANGING A TOXIN:   20
Polyvalent ligand tenaciously binds to cell-grabbing subunit of deadly Shiga toxin.

BUSINESS

BUSINESS CONCENTRATES: 23

FMC:   26
Restructuring of firm's industrial chemicals businesses pays off in 1999.

MAKING GLYCERIN:   28
Ethanol producer plans to recover, purify, and sell by-product glycerin.

SHIP AHOY:   30
Methanex's huge Millennium Explorer is on her maiden voyage.

CHINA:   33
Country's transition into a world trade partner will not proceed smoothly.

CEFIC'S HUGO LEVER:   41
Longtime leader steps down after steering European chemical industry through political, societal minefields.

PERSPECTIVE
SCIENCE & THE LAW:   49
Disconnects between legal and scientific truth seeking take on a new dimension in e-commerce.

GOVERNMENT & POLICY

GOVERNMENT CONCENTRATES:  62

BIOSAFETY PACT:   65
Protocol on transgenic products is finalized, leaving most parties reasonably satisfied.

FOREIGN STUDENT FEES:   74
Universities chafe under government rule to collect fee to track foreign students.

SCIENCE/TECHNOLOGY

SCIENCE/TECHNOLOGY CONCENTRATES:  79

PROTEOMICS CONFERENCE:   81
International experts address how genome sequences might best be analyzed, archived, and used.

PITZER TRIBUTE:   84
Late scientist's colleagues convene a conference on theoretical chemistry.

ENZYME COOPERATION:   86
X-ray crystal structure of DNA repair enzyme APE1 provides insight into enzyme pathways.

SPECIAL REPORT
COVER STORY
CUSTOM CHEMICALS:   91
Slowdowns in outsourcing production are hampering growth; firms regroup, add new technologies.

ACS NATIONAL AWARDS
2000 WINNERS:   119
Wasan, Wheelwright, Wolynes, Evans, Bercaw, Cane, Ellman, Herschlag, Kool, Padwa, Porter, Swager, Van Vranken, and Winkler.

THE DEPARTMENTS

   5 EDITOR'S PAGE

   8 C&EN ADVISORY BOARD

  13 LETTERS

  47 CHEMICAL HINDSIGHTS

  87 NEW PRODUCTS

 144 NEWSCRIPTS


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Copyright © 2000 American Chemical Society