Table of Contents - February 16, 2004

NEWS OF THE WEEK
			TUBULAR TRANSFER Tunneling nanotubes transport organelles from one cell to another.
			SLEEP DRUG DEAL Merck gains U.S. rights to Lundbeck's gaboxadol.
			VACCINE SAFETY Researchers disagree over preservative thimerosal's link to autism.
			DNA REPAIR MANUAL Structure reveals how enzyme finds and removes damaged base pair.
			NSF HEAD RESIGNS Director Rita Colwell will step down on Feb. 21.
			ALTERNATIVE FUELS Dow tests advanced fuel cell at Texas facility; Novozyme slashes cost of key enzyme for making renewable fuels.
			CORPORATE SCORECARD Chemical industry attains average ranking in accountability survey.
			ARCTIC FISH ANTIFREEZE Synthesis of glycoproteins helps explain how they inhibit ice formation.
			AGING ARMS STOCKPILE NRC report urges the Army to improve its monitoring of stored chemical weapons.

COVER STORY

PHARMA INDUSTRY
Major drug firms battle slump in new drug introductions by reorganizing and absorbing new tools for discovery and development; companies also face external pressures on the public, political, and regulatory fronts.

COVER: Abbott Laboratories photo

BUSINESS

BUSINESS CONCENTRATES

INFORMEX REVIEW
Annual custom chemicals conference focuses on kilogram-scale production, catalysis, and low-cost manufacturing.

GOVERNMENT & POLICY

GOVERNMENT CONCENTRATES

FEDERAL R&D
Proposed fiscal 2005 budget emphasizes defense and homeland security.

SCIENCE/TECHNOLOGY

SCIENCE/TECHNOLOGY CONCENTRATES

MOLD RISKS
There is growing concern over the health effects of indoor mold, and current building design and materials may be partly to blame.

NOVEL CHEMISTRY
At Informex, K. Barry Sharpless talked about click chemistry--a new approach to organic synthesis that's inspired by nature.

DIGITAL BRIEFS