H1N1 Pandemic
Quote of the Week
"It's very important for researchers to know that it makes no sense to fabricate data. It will always come out because science relies on reproducibility."
RALPH EICHLER, PRESIDENT, ETH ZURICH – p. 11
September 28, 2009
In This Issue:
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Highlights
Cover Story
Flu Fervor
In response to the H1N1 viral pandemic, manufacturers ramp up production of antiviral drugs; vaccine makers race to deliver doses in time. (pp. 15-26, 27-33)
Business
Stateside Surge In Pharma Chemicals (Member Content)
Investment flows into the U.S. as drugmakers reassess their supply chains. (pp. 38-41)
Science & Technology
Getting By On Little Water
Advances in breeding and basic science confer drought tolerance to crops. (pp. 60-62)
» Photo Gallery
Table of Contents
News Of The Week
Moon's Surface Holds Water p. 9
Planetary Science: Spectral results from three different spacecraft confirm presence of H2O or HO•.
Solar Cells Get Chemistry Help p. 10
Photovoltaics: Chemical makers see efficiency opportunity.
Progress, But No Breakthroughs p. 10
Climate-Change Summit: U.S., China endorse Copenhagen talks.
Data Manipulation At ETH p. 11
Misconduct: Fabricated chemistry data at Switzerland's premier research institution leads to resignation.
Biotech Stocks p. 11
Falling share prices could lead to market delisting for many firms.
Unusual Aluminum Bonding Geometry p. 12
Catalysis: Pentacoordinated Al joins Pt in supported catalysts.
Heads Butt Over Deadly Explosion p. 12
Dust Accident: Safety board seeks better maintenance; unions want tougher regulations.
Unearthing Nature's Bounty p. 13
Chemical Biology: Mass spectrometry anchors tactic for finding new natural products from microbes.
White House Honors Top Scientists And Inventors p. 13
Awards: Chemists among this year's winners of the National Medal of Science, National Medal of Technology.
Business
Stateside Surge In Pharma Chemicals pp. 38-41 (Member Content)
Investment flows into the U.S. as drugmakers reassess their supply chains.
Gaining Focus pp. 43-45 (Member Content)
Small-molecule drugs to treat dry age-related macular degeneration are heading to the clinic.
DuPont Accuses Scientist Of Theft pp. 47-48 (Member Content)
Colleagues, puzzled by charges, wonder whether it is all a misunderstanding.
Business Concentrates pp. 35-36 (Member Content)
- Green Lists Proliferate
- In advance of the United Nations-sponsored climate conference in Copenhagen in December, the magazine Newsweek and the Carbon Disclosure Project investors group separately issued rankings...
- Solvay Indupa To Cut One Plant
- Solvay’s South American affiliate, Solvay Indupa, is closing its polyethylene plant in Santo André, Brazil...
- Ineos Nova Shuts Another Plant
- Ineos Nova, the styrenics joint venture between Ineos and Nova Chemicals, is closing a 90,000-metric-ton-per-year polystyrene plant in Breda, the Netherlands...
- Lucite Closes A Third Unit
- Over the next few months, Lucite International will be closing its acrylonitrile plant, which employs 75 workers in Beaumont, Texas...
- Teijin, Chinese Firm Recycle Polyester
- Japan’s Teijin is working with the Chinese sports-apparel firm Li Ning to collect and recycle used polyester garments in China...
- Georgia Gulf Reworks Debt
- In a special meeting, Georgia Gulf shareholders approved an amendment to the company’s charter that increases the number of authorized shares of common stock to 100 million...
- Borealis Donates Polyethylene
- Borealis is donating polyethylene to make water pipe to supply temporary housing for 1,200 people in the earthquake-ravaged town of L’Aquila, Italy...
- Warner Sells Rights To Leo For $1 Billion
- Warner Chilcott is selling U.S. rights to topical psoriasis treatments and other development-stage dermatology products...
- Qiagen Acquires Diagnostics Maker
- Qiagen, a Dutch assay technology company, has acquired DxS, a diagnostics firm, for $95 million in cash, plus up to $35 million more if certain milestones are met...
- AstraZeneca Licenses Two Nektar Compounds
- AstraZeneca is licensing two drugs from Nektar Therapeutics that are being developed to treat opioid-induced constipation...
- New Technology Bows At Seattle Genetics
- Seattle Genetics has come up with a new technology that increases the potency of monoclonal antibodies...
- Animal-Health Deals In The Offing
- Pfizer and Wyeth have agreed to sell certain Wyeth animal-health assets to Boehringer Ingelheim...
- Business Roundup
- Makhteshim Agan Industries, Halocarbon Products, Arkema, American Pacific, Perstorp, Arch Chemicals, Chemtura, Wyeth Pharmaceuticals and Ambrx, SuperGen, Biogen Idec...
ACS News
Board, Council Meet In Washington pp. 70-72
Governance bodies receive reports, debate election procedure.
Rubber Division Oral History Collection Online p. 72
Oral-history interviews with innovators and leaders of the early rubber industry collected by the ACS Rubber Division are now available in a digital audio format.
Government & Policy
Innovators Score pp. 51-53 (Member Content)
Makers of brand-name biologics get closer to winning 12 years of exclusivity before generic versions can come to market.
Genetic Testing Goes Mainstream pp. 54-57 (Member Content)
Direct-to-consumer companies are proliferating, raising questions about quality and lack of standards.
Government & Policy Concentrates p. 50 (Member Content)
- Reporting CO2 Emissions
- Tens of thousands of industrial plants will have to report their emissions...
- More Oversight Of Biolabs Needed
- The federal government needs to do more to ensure the safety of high-containment laboratories...
- Court Rules Against Monsanto Beets
- USDA's approval of Monsanto's genetically engineered Roundup Ready sugar beets violated...
- Chemicals, Estrogens Targeted In Water
- Pharmaceutical estrogens, pesticides, and two major perfluorinated compounds are among...
- Rail Antitrust Bill Advances In House
- The House Judiciary Committee has approved legislation that would repeal the freight railroad...
Science & Technology
Getting By On Little Water pp. 60-62
Advances in breeding and basic science confer drought tolerance to crops.
» Photo Gallery
Targeting RNA pp. 63-66 (Member Content)
Unique challenges face developers of drugs that hit disease-related RNAs rather than disease-related proteins.
Inside Instrumentation p. 68 (Member Content)
Technology And Business News For The Laboratory World.
Science & Technology Concentrates pp. 58-59 (Member Content)
- Chirality’s Atmospheric Role
- Oxidation reactions of chiral organic molecules with ozone on aerosol particles in the atmosphere depend on the molecules’ stereochemistry.
- Direct RNA Sequencing
- Helicos BioSciences reports a method for direct RNA sequencing that avoids first converting RNA to complementary DNA.
- Listerias Soften Up Cells For Infection
- Scientists unravel a new mechanism by which pathogenic bacteria spread from cell to cell within an infected mammalian host.
- Tin Alkyne Analog’s On-Off Cycloaddition
- A tin analog of acetylene, a compound with a rare Sn≡Sn bond, reversibly adds ethylene across the triple bond under ambient conditions.
- Mass Spectrometry As A Surgical Tool
- An ambient ionization technique enables collection of mass spectra of tissue samples in real time during cancer surgery.
- Seek-And-Detox For Nerve Agents
- Small-molecule sensors not only detect organophosphorus chemical warfare agents but also disarm them in the process.
- Lattice Mismatches Limit Zeolites
- Chemists apply microscopy and spectroscopy methods to probe crystal defects that obstruct the diffusion of molecules through catalyst pores.
- Cod Fillets Keep Bad Proteins Away
- Proteins extracted from Atlantic cod have remarkable antifouling properties that keep metal and plastic surfaces free from gunk.
» more science & technology news...
Editor's Page
Pharmaceuticals Issue p. 3
The Departments
Letters pp. 4-7 (Member Content)
Newscripts p. 80
Bionic Eyesight, Cell-Phone Microscopes
This Week Online
C&EN Webinar
New C&EN Webinar on Outsourcing in Drug Discovery
Join us for the next C&EN Webinar, "Outsourcing is a Key Pathway in the Future of Drug Discovery."
Learn about the current state of outsourcing in the pharmaceutical industry and examine developments that have emerged in the past few years, including:
- Outsourcing drug discovery, including lead discovery and optimization
- Outsourcing to Asia
- Balancing cost and quality
- Pharma's R&D commitment to new drug development
- Outsourcing market's size and geography
This free webinar will be held Thursday, October 1, 2009, 1:00-2:00 PM ET. Register online.
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