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Quote of the Week

"It's very important for researchers to know that it makes no sense to fabricate data. It will always come out because science relies on reproducibility."
RALPH EICHLER, PRESIDENT, ETH ZURICHp. 11

September 28, 2009

In This Issue:

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October 24, 2011 Issue
October 17, 2011 Issue
October 10, 2011 Issue
October 3, 2011 Issue

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Highlights

Cover Story

Flu Fervor

In response to the H1N1 viral pandemic, manufacturers ramp up production of antiviral drugs; vaccine makers race to deliver doses in time. (pp. 15-26, 27-33)

Business

Stateside Surge In Pharma Chemicals (Member Content)

Investment flows into the U.S. as drugmakers reassess their supply chains. (pp. 38-41)

Science & Technology

Getting By On Little Water

Advances in breeding and basic science confer drought tolerance to crops. (pp. 60-62)

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Table of Contents

News Of The Week

Moon's Surface Holds Water Progress, But No Breakthroughs Heads Butt Over Deadly Explosion Unearthing Nature's Bounty

Moon's Surface Holds Water p. 9

Planetary Science: Spectral results from three different spacecraft confirm presence of H2O or HO.

Solar Cells Get Chemistry Help p. 10

Photovoltaics: Chemical makers see efficiency opportunity.

Progress, But No Breakthroughs p. 10

Climate-Change Summit: U.S., China endorse Copenhagen talks.

Data Manipulation At ETH p. 11

Misconduct: Fabricated chemistry data at Switzerland's premier research institution leads to resignation.

Biotech Stocks p. 11

Falling share prices could lead to market delisting for many firms.

Unusual Aluminum Bonding Geometry p. 12

Catalysis: Pentacoordinated Al joins Pt in supported catalysts.

Heads Butt Over Deadly Explosion p. 12

Dust Accident: Safety board seeks better maintenance; unions want tougher regulations.

Unearthing Nature's Bounty p. 13

Chemical Biology: Mass spectrometry anchors tactic for finding new natural products from microbes.

White House Honors Top Scientists And Inventors p. 13

Awards: Chemists among this year's winners of the National Medal of Science, National Medal of Technology.

Business

Stateside Surge In Pharma Chemicals pp. 38-41 (Member Content)

Investment flows into the U.S. as drugmakers reassess their supply chains.

Gaining Focus pp. 43-45 (Member Content)

Small-molecule drugs to treat dry age-related macular degeneration are heading to the clinic.

DuPont Accuses Scientist Of Theft pp. 47-48 (Member Content)

Colleagues, puzzled by charges, wonder whether it is all a misunderstanding.

Business Concentrates pp. 35-36 (Member Content)

  • Green Lists Proliferate
  • In advance of the United Nations-sponsored climate conference in Copenhagen in December, the magazine Newsweek and the Carbon Disclosure Project investors group separately issued rankings...
  • Solvay Indupa To Cut One Plant
  • Solvay’s South American affiliate, Solvay Indupa, is closing its polyethylene plant in Santo André, Brazil...
  • Ineos Nova Shuts Another Plant
  • Ineos Nova, the styrenics joint venture between Ineos and Nova Chemicals, is closing a 90,000-metric-ton-per-year polystyrene plant in Breda, the Netherlands...
  • Lucite Closes A Third Unit
  • Over the next few months, Lucite International will be closing its acrylonitrile plant, which employs 75 workers in Beaumont, Texas...
  • Teijin, Chinese Firm Recycle Polyester
  • Japan’s Teijin is working with the Chinese sports-apparel firm Li Ning to collect and recycle used polyester garments in China...
  • Georgia Gulf Reworks Debt
  • In a special meeting, Georgia Gulf shareholders approved an amendment to the company’s charter that increases the number of authorized shares of common stock to 100 million...
  • Borealis Donates Polyethylene
  • Borealis is donating polyethylene to make water pipe to supply temporary housing for 1,200 people in the earthquake-ravaged town of L’Aquila, Italy...
  • Warner Sells Rights To Leo For $1 Billion
  • Warner Chilcott is selling U.S. rights to topical psoriasis treatments and other development-stage dermatology products...
  • Qiagen Acquires Diagnostics Maker
  • Qiagen, a Dutch assay technology company, has acquired DxS, a diagnostics firm, for $95 million in cash, plus up to $35 million more if certain milestones are met...
  • AstraZeneca Licenses Two Nektar Compounds
  • AstraZeneca is licensing two drugs from Nektar Therapeutics that are being developed to treat opioid-induced constipation...
  • New Technology Bows At Seattle Genetics
  • Seattle Genetics has come up with a new technology that increases the potency of monoclonal antibodies...
  • Animal-Health Deals In The Offing
  • Pfizer and Wyeth have agreed to sell certain Wyeth animal-health assets to Boehringer Ingelheim...
  • Business Roundup
  • Makhteshim Agan Industries, Halocarbon Products, Arkema, American Pacific, Perstorp, Arch Chemicals, Chemtura, Wyeth Pharmaceuticals and Ambrx, SuperGen, Biogen Idec...

ACS News

Board, Council Meet In Washington pp. 70-72

Governance bodies receive reports, debate election procedure.

Rubber Division Oral History Collection Online p. 72

Oral-history interviews with innovators and leaders of the early rubber industry collected by the ACS Rubber Division are now available in a digital audio format.

Government & Policy

Innovators Score pp. 51-53 (Member Content)

Makers of brand-name biologics get closer to winning 12 years of exclusivity before generic versions can come to market.

Genetic Testing Goes Mainstream pp. 54-57 (Member Content)

Direct-to-consumer companies are proliferating, raising questions about quality and lack of standards.

Government & Policy Concentrates p. 50 (Member Content)

Science & Technology

Getting By On Little Water pp. 60-62

Advances in breeding and basic science confer drought tolerance to crops.

» Photo Gallery

Targeting RNA pp. 63-66 (Member Content)

Unique challenges face developers of drugs that hit disease-related RNAs rather than disease-related proteins.

Inside Instrumentation p. 68 (Member Content)

Technology And Business News For The Laboratory World.

Science & Technology Concentrates pp. 58-59 (Member Content)

Editor's Page

Pharmaceuticals Issue p. 3

The Departments

Letters pp. 4-7 (Member Content)

Newscripts p. 80

Bionic Eyesight, Cell-Phone Microscopes

This Week Online

C&EN Webinar

Outsourcing is a Key Pathway in the Future of Drug Discovery.

New C&EN Webinar on Outsourcing in Drug Discovery

Join us for the next C&EN Webinar, "Outsourcing is a Key Pathway in the Future of Drug Discovery."

Learn about the current state of outsourcing in the pharmaceutical industry and examine developments that have emerged in the past few years, including:

  • Outsourcing drug discovery, including lead discovery and optimization
  • Outsourcing to Asia
  • Balancing cost and quality
  • Pharma's R&D commitment to new drug development
  • Outsourcing market's size and geography

This free webinar will be held Thursday, October 1, 2009, 1:00-2:00 PM ET. Register online.

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