New Directions In R&D
Quote of the Week
"We need to follow the research wherever it leads us, without fear of the consequences of speaking truth to power."
BENJAMIN D. SANTER, CLIMATE SCIENTIST, LAWRENCE LIVERMORE NATIONAL LAB. – p. 31
June 7, 2010
In This Issue:
Jump to Table of Contents ↓
Highlights
Cover Story
Research Recalibrated
The spending race is over in pharmaceutical R&D, with companies now focused on doing more with less. (pp. 13-18)
» R&D On The Chopping Block
Business
Growing Chemicals
New biotech traits enable fuel and polymer production in crops. (pp. 25-28)
Government & Policy
Climate Debate Turns Foul(Member Content)
Scientists are being intimidated and harassed because of their research, they tell Congress. (pp. 31-32)
Table of Contents
News Of The Week
House Passes Science Bill p. 9
Legislation: Third time's the charm for the measure to bolster science research, education, and innovation.
Bock To Head BASF In 2011 p. 10
Succession: Finance chief gets nod to lead chemical industry icon.
Metabolites Turn On Pathogen's Virulence p. 10
Natural Products: Staph produces molecules that help it colonize humans.
Catalysis In Crystals p. 11
Inorganic chemistry: Single crystals of iridium complex can exchange ligands and hydrogenate ethylene.
Drug Prices p. 11
Companies to pull products from Greek market after price cuts.
FDA Approval Is Not A Shield p. 12
Liability: Like brand-name companies, generic drug firms can be sued for not warning about risks.
Downsizing Ethylene p. 12
Petrochemicals: Two Japanese firms prepare for onslaught of Middle Eastern capacity.
Business
Eastman Finds Its Stride pp. 21-23 (Member Content)
Executives have sworn off reinvention, instead focusing on what they think the company does best.
Growing Chemicals pp. 25-28
New biotech traits enable fuel and polymer production in crops.
In Pursuit Of Purity p. 29 (Member Content)
Private equity firm forays into high-purity chemicals with former Rohm and Haas CEO Raj Gupta.
Business Concentrates pp. 19-20 (Member Content)
- J&J Strengthens Its Respiratory Pipeline
- Johnson & Johnson has snapped up several small-molecule assets to bolster its respiratory drug pipeline...
- Dow’s Credit outlook Upgraded By Fitch
- Fitch Ratings has raised its outlook on Dow Chemical’s BBB credit rating from negative to stable...
- Dow Is Selling One European Facility To Monument …
- Indiana-based specialty hydrocarbons maker Monument Chemicals has acquired a multipurpose facility in Antwerp, Belgium, from Dow Chemical...
- Japan’s Arakawa
- Osaka, Japan-based Arakawa Chemical has initiated talks with Dow Chemical for the acquisition of a 15,000-metric-ton-per-year hydrogenated hydrocarbon resins plant...
- OCI And Cabot Hike Asian Carbon Black
- South Korea’s OCI plans to build a $60 million carbon black plant in Gunsan, South Korea...
- Evonik Ups Silica, Nylon Intermediate
- Citing high demand, Evonik Industries is expanding capacity for a nylon intermediate and precipitated silica...
- Borealis Opens One Plant, Plans Another
- Borealis, the Austrian polyolefins firm, has opened a $500 million high-pressure, low-density polyethylene plant in Stenungsund, Sweden...
- Leukemia Group Backs Onconova Treatment
- Onconova Therapeutics and the Leukemia & Lymphoma Society have partnered to push Estybon toward commercialization...
- Radiochemical Supplies Enhanced
- Lantheus Medical Imaging has received U.S. approvals to use molybdenum-99 from the Nuclear Research Institute in Rez, Czech Republic...
- Grace Opens Aussie Construction Plant
- W.R. Grace has opened a new site in Epping, Australia, to serve construction industry customers in Australia, New Zealand, and nearby Pacific islands...
- BASF Will Enter L-Menthol Market
- BASF has started constructing what it says will be the world’s largest plant for the aroma chemical L-menthol...
- SEC Charges Biotech R&D Head With Lying
- The Securities & Exchange Commission has charged Elizabeth A. Dragon with making false statements to investors about her company’s prenatal...
- Business Roundup
- DuPont, Dow Corning, DSM, Nichia, Air Liquide, Sanofi-Aventis, VaxGen, Sanofi-Aventis, Tetraphase Pharmaceuticals...
Meetings
2010 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community is for June through December.
This Week Online
Reel Science
"Splice"
Reel Science sifts through the schlock to review a film depicting
genetic engineering gone terribly wrong.
» read more...
Government & Policy
Climate Debate Turns Foul pp. 31-32 (Member Content)
Scientists are being intimidated and harassed because of their research, they tell Congress.
Health Agencies Under Scrutiny pp. 33-34 (Member Content)
Congress, GAO point to consistent flaws in CDC units’ environmental health practices.
Greenpeace Targets DuPont Facilities pp. 35-36 (Member Content)
Environmental group draws attention to risks posed by use of toxic chemicals.
Government & Policy Concentrates p. 30 (Member Content)
- EPA Proposes Pesticide Permit
- EPA has released a draft pesticide permit that sets the stage for a debate about pesticide spraying activities...
- UVA Challenges Climate Grant Probe
- The University of Virginia is pushing back against Virginia Attorney General Kenneth T. Cuccinelli II’s fraud probe...
- Formaldehyde Linked To Cancer In Humans
- Formaldehyde is carcinogenic when inhaled by humans, EPA concludes...
- Report Looks At REACH Compliance
- A new report finds 24% noncompliance levels among companies inspected for their enforcement of Europe’s Registration, Evaluation, Authorization & Restriction of Chemical substances...
- House Passes R&D Tax Credit Bill
- The House of Representatives passed a $116 billion bill that includes a one-year retroactive renewal of the R&D tax credit...
» more government & policy news...
People
Obituaries p. 44 (Member Content)
Social Networking And C&EN
You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.
Science & Technology
Enzyme's Metal Cluster Is Nailed pp. 39-40 (Member Content)
Definitive solution of the structure of an enzyme in isoprenoid biosynthesis could lead to new antibiotics.
Palladium-Mediated Insertive Behavior p. 41 (Member Content)
Studies pin down key intermediates in versatile migratory alkene insertion reactions.
Imaging Single Atoms In Zeolites p. 42
Materials: Microscopy method reveals positions of catalytic metals anchored inside pores.
Mother Nature's Tenuous Respite p. 43 (Member Content)
Insights: Forty years of environmental protection is showing some benefits.
Science & Technology Concentrates pp. 37-38 (Member Content)
- Needling Adenosine
- Acupuncture appears to stimulate release of the natural painkilling compound.
- Clay Layers Help Fabrics Fight Flames
- A polymer-montmorillonite layered composite imparts flame resistance to clothing and other materials.
- Imaging Enzyme Replacement Therapy
- PET imaging is used for the first time to monitor therapeutic enzyme distribution and lifetime.
- New Molecular Way To Combat The Flu
- Microbiologists uncover a new protein target and a small molecule that inhibits the protein.
- Atmospheric Trioxy Radical Idea Banished
- Transient fusing of O2 and ·OH to form ·HO3 doesn’t seem to be important in atmospheric chemistry.
- Glowing Proteins On The Spot
- Mutant bacterial enzyme labels proteins site-specifically inside live cells.
- Tagging Peptides Enables C-Terminomics
- A strategy is unveiled for easily finding proteins activated by cleavage at the C-terminus, rather than the N-terminus.
- Waste Plastics Become Functional Carbon Microspheres
- Plastic bags are “upcycled” into a material that could find new life printer toner, tires, and more.
» more science & technology news...
Editor's Page
Ganging Up On Chemicals p. 5
The Departments
Letters pp. 6-7
Newscripts p. 48
Dissolvable Design, MJ In The Classroom, Chemistry Snack Time
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