Clot-Preventing Drugs
Quote of the Week
"A better understanding of exposures will exonerate the majority of chemicals people are afraid of."
TINA BAHADORI, EXPOSURE SCIENTIST AND MANAGING DIRECTOR, LONG-RANGE RESEARCH INITIATIVE, AMERICAN CHEMISTRY COUNCIL – p. 42
August 16, 2010
In This Issue:
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Highlights
Cover Story
To Clot, Or Not
Anticoagulants in the pipeline may overcome the drawbacks of well-entrenched drugs. (pp. 15-22)
Government & Policy
Recasting TSCA(Member Content)
Congressional hearing probes safety and other provisions of bill to reform chemical control law. (pp. 35-37)
Science & Technology
Exposing The Exposome(Member Content)
Individuals' records of environmental exposures may yield clues to the causes of disease. (pp. 32-33)
Table of Contents
News Of The Week
A Wire For Spying On Cells p. 9
Nanotechnology: Tiny bioprobe features a field-effect transistor built from a kinked silicon nanowire.
Economy Buoys Chemical Deals p. 10
Business: Acquisitions are brisk for the first half of 2010.
OSHA Levies Fine For Fatal Explosion p. 10
Safety: Agency cites 371 violations but stops short of prohibiting use of natural gas for pipe cleaning.
Reviving An Antibiotic Target p. 11
Structural Biology: Novel binding interaction could lead to new class of antibacterial drugs.
Directing Materials Research p. 11
Engineering professor Ian M. Robertson will head the Materials Research Division at NSF.
Activists, Industry Clash Over Security p. 12
Antiterrorism: Chemical companies use financial clout to thwart stricter measures, report charges.
DSM Tries Again To Sell Special Products Unit p. 12
Divestitures: Earlier attempt was blocked by antitrust authorities.
Setting Sites On Sustainability p. 13
ACS News: Chemical societies’ websites focus on global environmental challenges.
Industrial Biotechnology p. 13
Firms move to commercialize biobased fuels and chemicals.
Business
Strong Demand Buoys Chemicals pp. 26-28 (Member Content)
Jump in earnings in the second quarter might be difficult to maintain.
Pharma Continues Its Turnaround pp. 30-32 (Member Content)
Second-quarter earnings rise despite restructuring moves, product problems, and manufacturing issues.
A Chinese Chemical Supplier Matures p. 33 (Member Content)
Intermediates provider Kingchem adds capabilities to withstand competition.
Business Concentrates pp. 24-25 (Member Content)
- Merck To Buy Back Cherokee Pharmaceuticals
- Counter to industry trends and its own moves to shed manufacturing operations, Merck & Co. has agreed to buy back a former facility in Riverside, Pa...
- Dow Corning Invests In Silicon Metal
- Dow Corning has agreed to pay nearly $40 million for a 49% interest in Timminco’s silicon metal facility in Bécancour, Quebec...
- ADM Adds Isosorbide To Biobased Slate
- Archer Daniels Midland has begun offering isosorbide as part of its slate of chemicals derived from renewable resources...
- Nippon Shokubai Hikes Superabsorbents
- Seeking to enhance its role as a top global supplier of superabsorbent acrylic polymers, Japan’s Nippon Shokubai will build a new plant in Indonesia...
- SEC Charges Two In Bribery Case
- The Securities & Exchange Commission has charged David P. Turner and Ousama M. Naaman...
- Teijin To Spin Off Polyester Business …
- Teijin will spin off its Japanese polyethylene terephthalate (PET) resin business into a venture with Mitsui Chemicals...
- … And Buy U.S. Materials Company NanoGram
- Teijin has acquired NanoGram, a Milpitas, Calif.-based nanomaterials firm that employs 25 people...
- Hong Kong Gets DuPont Solar Modules
- DuPont supplied the thin-film photovoltaic modules that were recently installed at Hongkong Electric’s Lamma Power Station...
- GSK And Vectura Sign Licensing Deal
- GlaxoSmithKline and Vectura have signed a licensing agreement under which GSK will gain nonexclusive rights to Vectura’s dry-powder drug formulation technology...
- P&G To Use Braskem Renewable Plastic
- Procter & Gamble plans to use sugarcane-derived high-density polyethylene for select packaging of its Pantene Pro-V...
- Endo Will Acquire Drug Partner Penwest
- Endo Pharmaceuticals plans to acquire drug delivery technology specialist Penwest Pharmaceuticals...
- Sigma-Aldrich Expands Boronic Acid Deal
- Sigma-Aldrich has signed a licensing agreement with the University of Illinois, Urbana-Champaign, enabling it to expand the range of boronic acid surrogates...
- Medicago Advances Vaccine Production
- Canada’s Medicago has been awarded a $21 million grant...
- Business Roundup
- The European Commission, Cristal Global, Eastman Chemical, Chemtura, Ashland, Dow Chemical, Tata Chemicals, Sanofi-Aventis...
Employment
Connecting In New England pp. 48-50
For new grads searching for a job in this tough economy, networking is not an option but a necessity.
Resources For Chemists: In The Job Market? Get Out There And Network p. 50
Government & Policy
Recasting TSCA pp. 35-37 (Member Content)
Congressional hearing probes safety and other provisions of bill to reform chemical control law.
A Focus On The Cause: Rallying For Congress To Overhaul U.S. Chemical Production Law p. 36 (Member Content)
Public-Access Debate Continues p. 38 (Member Content)
Supporters and opponents of free access to all federally funded published research argue anew at congressional hearing.
Modern Agriculture p. 28 (Member Content)
Insights: Industry gears up to promote benefits of chemicals, new technologies.
Government & Policy Concentrates p. 34 (Member Content)
- EPA Proposes Changes To Chemical Data Reports
- Chemical makers would have to provide data about production, processing, and use of their compounds every four years...
- Chu Revives Energy Advisory Panel
- Energy Secretary Steven Chu last week reestablished the Energy Advisory Board that was dismantled by the Bush Administration in 2006...
- Milestone Reached At Umatilla Depot
- The Umatilla Chemical Depot, in eastern Oregon, has passed the halfway mark for eliminating its stockpile of chemical warfare agents...
- Gasification Plant Funds Shifted By DOE
- What was to be the first commercial-scale gasification plant to generate electricity and capture and sequester CO2 underground was canceled...
- Rail Agency Forms Committee On Toxics
- The federal Surface Transportation Board is forming an advisory committee to study and suggest ways to safely move toxic cargo...
» more government & policy news...
Social Networking And C&EN
You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.
Science & Technology
Exposing The Exposome pp. 42-44 (Member Content)
Individuals' records of environmental exposures may yield clues to the causes of disease.
Safeguarding NASA's Moon Rocks pp. 46-47 (Member Content)
Lab at Johnson Space Center preserves 40-year-old lunar samples for study.
Science & Technology Concentrates pp. 40-41 (Member Content)
- Peptide Rounds Up Amyloid-β
- Potential Alzheimer's drug renders toxic amyloid-β oligomers into innocuous clumps.
- Fullerene-like Boron Analog Reevaluated
- B80 is likely to have an unsymmetrical core-shell structure, not a symmetrical hollow cage structure as previously thought.
- Isotopes Help Home In On Ancient Rock
- Arctic region lava samples provide an unprecedented view of nascent Earth's geochemical evolution.
- Computations Clarify Oxidation Pathways
- Radical oxidation of vinyl alcohol follows different routes in atmospheric and combustion processes.
- Drug Design Leads To Desired Enzyme Inhibitors
- Non-bisphosphonate inhibitors of farnesyl pyrophosphate synthase could lead to cancer treatments.
- SANE Approach To Soft Lithography
- Method offers an easy way to make many different patterns starting with a single master pattern.
- Role Of Iron Regulatory Proteins Ironed Out
- On top of other functions, IRPs make it possible for cell mitochondria to maintain proper iron balance.
- Scaffolding Ligand Directs Quaternary Carbon Synthesis
- A bifunctional amine-phosphine ligand is proving to be a versatile directing group for organic syntheses.
» more science & technology news...
ACS Meetings
» 240th ACS National Meeting: Technical Program
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2010–11 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community is for August 2010 through June 2011.
Editor's Page
This And That p. 5
The Departments
Letters pp. 6-7
Newscripts p. 56
Mattress Scare Tactics, Squeaky-Clean Videos
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