Process Chemistry

Quote of the Week
"The trouble with famous scientists then and now is that it can be very difficult for others to successfully attack their theories."
MICHAEL LAING, RETIRED CHEMISTRY PROFESSOR, UNIVERSTIRY OF KWAZULU-NATAL, IN SOUTH AFRICA. – p. 60
September 6, 2010
In This Issue:
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Highlights

Cover Story
From A Teaspoon To A Ton
ACS Meeting News: Process chemists master the task of scaled-up pharmaceutical synthesis. (pp. 17-28)

Science & Technology
When Science Went International
Looking back 150 years at the conference that led to the assembly of the periodic table.. (pp. 60-62)

ACS Elections
Election Statements
Candidates for ACS president-elect and directors share their views and goals. (pp. 76-87)
Table of Contents
ACS Elections
Election Statements pp. 76-87
Candidates for ACS president-elect and directors share their views and goals.
For President-Elect: Luis A. Echegoyen pp. 76-77
For President-Elect: Bassam Z. Shakhashiri pp. 77-78
For District II Director: George M. Bodner pp. 79-80
For District II Director: Joseph R. Peterson pp. 80-81
For District IV Director: Larry K. Krannich pp. 81-82
For District IV Director: Will E. Lynch pp. 82-83
For Director-At-Large: Janan M. Hayes pp. 83-84
For Director-At-Large: Robert L. Lichter pp. 84-85
For Director-At-Large: Kathleen M. Schulz pp. 85-86
For Director-At-Large: Kent J. Voorhees pp. 86-87
News Of The Week
Covering Up For A Clear View p. 11
Surface Science: A blanket of graphene helps reveal the structure of water lying underneath.
Two Firms Near Bankruptcy Exit p. 12
Reorganization: Chemtura and Tronox reach agreements that could soon end court supervision.
Technique Combo Beats NMR Solo p. 12
Structural Biology: Combined strategy yields largest-ever solution structures.
Sanofi Comes Out With Genzyme Bid p. 13
Takeover: After being rejected by the biotech firm's management, Sanofi makes its case with shareholders.
New Hope For Malaria p. 13
Compound cures mice in one dose, works by a mechanism different from that of existing drugs.
Probing Individual Chemical Events p. 14
Imaging: Method tracks single-molecule reactions spatially and temporally.
Nanopore-Based Screening p. 14
DNA Analysis: Method detects single molecules passing through holes in graphene.
Academies Review Climate Panel p. 15
Climate Change: UN panel needs new leadership, says coalition of national science academies.
Investing In Biologics p. 15
Lonza and ScinoPharm strike deals that will expand their capabilities in biologic drugs.
Business

Taking The Measure Of The New Agilent pp. 32-33 (Member Content)
As it completes the integration of Varian, the scientific instrument maker looks for growth opportunities.
Making Clearer Polypropylene pp. 34-37 (Member Content)
Additive makers say their latest clarifiers extend the reach of the versatile polymer.
Funding Eases For Indian Drugmakers pp. 38-40 (Member Content)
Recovery of financial markets brings new sources of capital to India's pharmaceutical chemical sector.
Translational R&D pp. 42-43 (Member Content)
ACS Meeting News: Distinguishing between invention and innovation in creating jobs and wealth.
Betting On Lithium pp. 44-45 (Member Content)
Novolyte gears up to supply critical electrolytes for car batteries.
Business Concentrates pp. 30-31 (Member Content)
- Lithium Fund Lists On New York Stock Exchange
- Executives of Global X Funds, a firm that manages exchange-traded funds, recently rang the opening bell at the New York Stock Exchange to celebrate the listing of the Lithium Exchange Traded Fund...
- SABIC Getting Into Oleochemicals
- Saudi Basic Industries Corp. affiliate Saudi Kayan has inked an agreement with the German engineering firm Lurgi to build an oleochemical facility in Al Jubail, Saudi Arabia...
- Showa Denko To Add Chemical Alumina
- Japan’s Showa Denko plans to build a chemical alumina plant in West Kalimantan, Indonesia, in partnership with Indonesian mining firm Antam...
- Westlake Chemical expands Chlorine
- Westlake Chemical is moving forward with plans to build a new chlor-alkali unit at its Geismar, La., vinyls complex...
- Makhteshim Calls Off Albaugh Deal
- Makhteshim Agan Industries, the Israel-based off-patent crop protection specialist, has ended talks to acquire Iowa-based Albaugh...
- Governments Boost Renewable Energy
- Two renewable energy firms have plans to operate large-scale facilities with the support of local governments...
- Airgas, Air Products Fight In Court
- Airgas has sent a letter to the Delaware Court of Chancery arguing that attempts by Air Products & Chemicals to amend Airgas’ bylaws through a vote...
- Petronas Takes On BP Petrochemical Assets
- Malaysian oil producer Petronas is paying BP $363 million for the British company’s share of two petrochemical plants in Malaysia...
- Pfizer acquisition Targets Protein Misfolding
- Pfizer will purchase privately held FoldRx Pharmaceuticals, of Cambridge, Mass., for an undisclosed upfront fee and future milestone payments...
- Fujifilm Invests In Medical Materials
- Fujifilm has acquired a 41% stake in Tokyo-listed Japan Tissue Engineering (J-Tec), a firm that aims to develop tissue-engineered medical materials...
- Air Liquide, Praxair Invest in Mideast
- Industrial gas producer Air Liquide is investing about $75 million in Middle Eastern oxygen plants...
- Cerbios Opens Plant For Potent Drugs
- Cerbios Pharma, a Swiss drug ingredients maker, has opened a new plant for high-potency active ingredients at its site in Barbengo, Switzerland...
- Bayer gets Kythera’s Chin Fat Drug
- Intendis, the dermatology unit of Bayer HealthCare, will pay $43 million upfront for access to Kythera Biopharmaceuticals’ ATX-101, in late-stage trials to reduce small amounts of fat from under the chin...
- Business Roundup
- American Vanguard, Rhodia, Univar, Eka Chemicals, Gelest, Mascoma, Monsanto, Cipla...
ACS News
ACS Relaunches Journal of Combinatorial Chemistry p. 73
Scenes From The ACS Meeting In Boston p. 74-75
Government & Policy

Reality Check On Science At FDA pp. 48-50 (Member Content)
Facing huge challenges, agency wields meager resources.
Formaldehyde In Clothing pp. 51-54 (Member Content)
GAO study confirms that levels are low and health risk is likely very small.
Judge Halts Virginia Climate Probe p. 56 (Member Content)
Attorney general to issue new order to force university to provide researcher's data, e-mails.
Government & Policy Concentrates p. 46 (Member Content)
- VA Expands Benefits To Agent Orange Victims
- Vietnam veterans exposed to the herbicide agent orange are now eligible to receive service-related compensation for more illnesses...
- Cadmium Petition Granted By EPA
- EPA is granting a petition filed by a coalition of environmental groups in May to take regulatory action against cadmium in toy jewelry and other consumer products...
- EU Proposes Action On 10 Chemicals, Acids
- The European Union is deciding whether to target 10 industrial chemicals and a group of chromic acids for rigorous regulation...
- Chemtura Loses NAFTA Trade Case
- A three-member arbitration panel has rejected claims by Chemtura that the Canadian government violated the North American Free Trade Agreement when it phased out use of the insecticide lindane for seed treatment...
- HHS Funds Work On Multiuse Antibiotic
- The Biomedical Advanced Research & Development Authority (BARDA), has awarded a $64 million contract to Achaogen to develop a novel antibiotic for use against bioterrorism agents and as treatment of antibiotic-resistant infections...
» more government & policy news...
ACS Comment
Advocating For A Reviving Economy p. 71 (Member Content)
Awards

Social Networking And C&EN
You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.
Science & Technology

When Science Went International pp. 60-62
Looking back 150 years at the conference that led to the assembly of the periodic table.
Behind A Metal Makeover pp. 63-64
ACS Meeting News: To ensure their survival, pathogenic bacteria turn to manganese, not iron, when making an essential metalloenzyme.
Transition State Captured By Force pp. 65-66 (Member Content)
Stretching a polymer changes the way it isomerizes.
What's That Stuff? Road Markings p. 67
Pigments, polymers, and reflective spheres help keep you safe on the road.
Science & Technology Concentrates pp. 58-59 (Member Content)
- H2 At The Tip Of STM Boosts Resolution
- STM resolution of complex organic molecules can be greatly enhanced by modifying the tip
- Binding Site Broadens Prospects For Prostate-Cancer Drugs
- Scientists have found a new binding site in prostate-specific membrane antigen, a cancer-cell-surface receptor
- Calculated NMR Approach Improves Isomer Identification
- A probability measure works unusually well in matching calculated and experimental spectra
- Solvation Shell Helps Track Charge Transfer
- Researchers report monitoring ultrafast charge transfer in a dye molecule via the IR spectrum of its solvent shell
- Altruistic Bacteria Thwart Antibiotic
- Highly resistant bacteria produce extra indole to help their less resistant siblings survive a norfloxacin assault
- Nature's Route To Sunscreen Revealed
- Cyanobacteria are found to use a multienzyme pathway to build small molecules for sun protection
- Petal Shapes From A β–Peptide
- A research team has identified a β–peptide that self-assembles to form unprecedented 3-D structures
- Another Target For Alzheimer's Drugs
- A molecular probe fashioned from a cancer drug that inhibits amyloid-β helps uncover γ-secretase activating protein
» more science & technology news...
Books

Navigating A Risky World pp. 68-70
Exploring the ways people perceive risk and how they act accordingly.
ACS Meetings
2010–11 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community is for September 2010 through June 2011.
Editor's Page
Please Write And Please Vote p. 5
The Departments
Letters pp. 6-9
Newscripts p. 96
Stadium Food Chemistry, What's In A Name?
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