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Quote of the Week
"These days, you can't expect a job to last more than three to five years before mergers and restructuring force you to look for new prospects."
DANIEL E. LEVY, FOUNDER DEL BIOPHARMA – p. 49
April 18, 2011
In This Issue:
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Highlights
Cover Story
Farm Market
Agricultural chemical makers strive to bring to market pesticides with new modes of action, targets. (pp. 13-17)
Science & Technology
Unveiling Drug Candidates (Member Content)
ACS Meeting News: Medicinal chemists reveal potential drugs for HIV, Alzheimer's, diabetes, and irritable bowel syndrome. (pp. 37-41)
Career & Employment
Survival Skills
For the long-term unemployed, the key to finding a new job is to keep skills sharp. (pp. 49-51)
Table of Contents
Cover Story
Germinating Pesticides pp. 13-17
Chemical firms change course in the search for new products for agriculture.
Life After Roundup Web Exclusive
Weed Science: The emergence of glyphosate-resistant weeds has put agriculture in a quandary.
Going Mainstream: Biopesticide Producers Look Beyond Organic Growers p. 16
News Of The Week
Picking Up The Pace Of Evolution p. 7
Molecular Biology: Method speeds lab-based molecular evolution.
Congress Moves Forward On 2011 Budget p. 8
Government: Agreement on spending cuts averts a shutdown but will halt expansion plans for several science agencies.
Firms Target Biomethionine p. 8
Feed Additives: French and South Korean companies join for new route to amino acid.
Heterogeneous Tandem Catalysis p. 9
Catalysis: Nanostructured layered material performs multistep reaction.
Renewable Chemicals p. 9
OPX collaborates with Dow for biobased acrylic acid.
Doubting EPA On Formaldehyde p. 10
Risk: Science panel says agency failed to support chemical's link to leukemia, other health problems.
Chlorination Improves Organic Electronics p. 10
Materials: Treatment could simplify manufacturing, reduce costs.
Business
Rules Of Engagement pp. 21-23 (Member Content)
European companies and universities increasingly join forces for R&D.
Patchwork: Intellectual Property Rights Vary Across Europe Web Exclusive
Euticals Makes Its Global Move pp. 24-25 (Member Content)
The small Italian pharma chemicals firm harnesses Archimica.
Business Concentrates pp. 18-19 (Member Content)
- Amgen And Merck Move On Emerging Markets
- Amgen and Merck & Co. have struck deals that will expand their activity in emerging markets...
- Arch Boosts Bleach, Settles With Osmose
- Arch Chemicals has undertaken a two-year, $30 million project to install new calcium hypochlorite slurry drying technology at its Charleston, Tenn., plant...
- Styron Has New Name, Plans Latex In China
- Styron plans to change its name to Trinseo...
- Wacker Breaks Ground In Tennessee
- Germany’s Wacker Chemie broke ground in Cleveland, Tenn., on a 15,000-metric-ton-per-year polysilicon plant...
- Evonik To Set Up Lighting R&D Center
- Evonik Industries plans to set up an R&D unit called Light & Electronics at Taiwan’s Hsinchu Technology Park...
- Indorama To Hike European Polyester
- Indorama Ventures will expand its European polyethylene terephthalate (PET) capacity by 220,000 metric tons per year...
- Alcoa And Codexis Pursue Carbon Capture
- Alcoa has launched a pilot program with Codexis and CO2 Solution aimed at sequestering carbon dioxide emissions...
- Rivertop Invests In Glucaric Acid
- Biobased chemicals start-up Rivertop Renewables will expand its laboratories and build a semiworks facility in Missoula, Mont...
- One Whitesides Firm Acquires Another
- Nano Terra, a nanotechnology firm cofounded by Harvard University chemist George M. Whitesides, has acquired Surface Logix...
- Vertex, CF Foundation Extend R&D Pact
- Vertex Pharmaceuticals could receive up to $75 million in R&D funding over the next five years...
- Blueprint Medicines Is Oncology Start-Up
- Blueprint Medicines, a cancer drug discovery firm, has launched with $40 million in financing led by Third Rock Ventures...
- Lanxess Expanding Specialty Rubber
- Lanxess is boosting capacity for its Therban hydrogenated nitrile butadiene rubber by 40% at plants in Orange, Texas, and Leverkusen, Germany...
- Endo Will Acquire Medical Device Maker
- ndo Pharmaceuticals has agreed to buy American Medical Systems...
- Business Roundup
- Braskem, Arkema, Makhteshim Agan Group, LDK Solar, PerkinElmer, AMRI, Dainippon Sumitomo Pharma, Pfizer and Zacharon Pharmaceuticals, Takeda Pharmaceutical...
Career & Employment
Survival Skills pp. 49-51
For the long-term unemployed, the key to finding a new job is to keep skills sharp.
How To Craft An Attractive Résumé Web Exclusive
This Week Online
Where's the (Drug-Free) Beef?
Proteomics: Changes in protein expression could uncover cattle treated illicitly with growth-promoting hormones.
Pollution Turns Red Into Black
Art Conservation: Atmospheric sulfur dioxide blackens pigments in Pompeian frescoes.
Cutting Household Carbon Footprints
Climate Change: New online tool helps calculate the best ways to reduce emissions.
Latin American Petrochemical Meeting
C&EN Senior Editor Alex Tullo reports from the Petrochemical Networking Meeting in Houston.
Government & Policy
Food Dye Debate Resurfaces pp. 27-31 (Member Content)
FDA considers evidence to support link between behavior and artificial colors.
EPA Moves On Vapor Intrusion pp. 32-34 (Member Content)
Regulations are under way despite gaps in understanding how chemical vapors invade buildings.
Government & Policy Concentrates p. 26 (Member Content)
- Lawmakers Push EPA To Finish Dioxin Document
- Pressure on EPA to finish its risk reassessment of dioxins ramped up last week...
- Offshore Drilling Reviewed
- Representatives from the offshore oil and gas drilling industry assured Congress that they are improving safety standards for deepwater drilling...
- House Democrat Seeks Chemicals Data
- A key member of Congress is asking top executives at 15 chemical companies whether their firms produce or process persistent, bioaccumulative, and toxic (PBT) substances...
- Patent Office Will Add A Fast Track In May
- The Patent & Trademark Office (PTO) says it will begin accepting requests for expedited patent examination...
- DOE Targets Solar R&D
- The Department of Energy has announced that it will invest nearly $170 million in several areas of solar photovoltaic technology...
» more government & policy news...
Awards
pp. 46-47 (Member Content)
- Othmer Gold Medal To Kazuo Inamori
- L’Oréal Honors Women Chemists
- Nanoscience Award To Catherine Murphy
- Arthur Nozik Wins Esselen Award
- Dallas-Fort Worth Honors Coffer And Cruze
- Remsen Award To Graham Fleming
- De Clercq And Fauci Win Janssen Award
- Florida Award To Frank Millero
- Herty Award To Mark Wightman
- Alice Chen Garners Lemelson-MIT Student Prize
- Graduate Students Win Awards For Cancer Research
- Applications Sought For Pauling Award
- Call For Nominations For Bower Award
People
Social Networking And C&EN
You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.
Science & Technology
Unveiling Drug Candidates pp. 37-41(Member Content)
ACS Meeting News: Medicinal chemists reveal potential drugs for HIV, Alzheimer's, diabetes, and irritable bowel syndrome.
Where Are They Now? Revisiting Disclosures From Years Past p. 38(Member Content)
An Alternative Methylation Route pp. 42-43 (Member Content)
ACS Meeting News: Details of bacterial enzymes' unusual methylation step may help fight antibiotic resistance.
SciFinder's New Tool p. 45 (Member Content)
SciPlanner lets chemists visually interact with Chemical Abstracts Service data.
Science & Technology Concentrates pp. 35-36
- Meth Vaccine Revamped
- New methamphetamine analogs elicit antibodies to squelch the addictive drug’s activity
- Rechecked Meteorite Yields New Mineral
- Tiny deposits of wassonite, a TiS mineral, provide more details on the formation of the solar system
- Silicon Radicals Double Up
- Using carbon analogs as a guide, a Japanese team has synthesized the first stable silicon diradical species
- Peptide Denies Cell Entry To Ebola Virus
- With a newly designed peptide, scientists have developed a way to inhibit the deadly virus
- Ion Migration In Electrodes Revealed
- Fluorosulfate materials reveal differences in Na+ and Li+ movement, a finding that could improve rechargeable batteries
- Shorter Route Refines Total Synthesis Of Anticancer Agent
- A new preparation of the natural product englerin A requires6 fewer steps and has a better overall yield
- Green-Lighting Boron Carbide
- A new pyrotechnic material burns green in color, is greener for the planet, and is easy on the greenbacks
- Cell Antennas Tune In To Chemical Signals
- Thin, fingerlike protrusions are essential in aiding cells to trace molecular messages they need for development
» more science & technology news...
Meetings
2011 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community.
Editor's Page
Scientific Literacy p. 5
The Departments
Letters p. 6
Newscripts p. 56
Intoxicated Metals, Hangover Relief, Prehistoric Reptile Skin
C&EN Archives
Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.
Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives
Environmental SCENE News
Fertilizer May Help Bacteria Slip Into Groundwater
Water Safety: High phosphate levels allow deadly microbes to pass through soil.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Sunlight Is An Effective Disinfectant
Public Health: Field work shows that a cheap water treatment method improves children's health.
House Takes Aim At Clean Air Act
Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.
Analytical SCENE News
New Method Isolates Membrane Proteins
Protein Purification: Technique separates proteins on a lipid bilayer.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Mapping Drugs In Human Tissue
Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.
Skeletons Come To Light
Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.
Analyzing Nuclear Processes
ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.
JACS Research In C&EN
Indole Changeup Yields Elusive Alkaloid
ACS Meeting News: Cyclization and nitrene insertion star in synthesis.
Prefab Synthesis Moves Ahead
Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.
Multiple Bradykinin States Revealed
The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.
Scaling Up The Axinellamines
A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.
A Revamped Vancomycin
Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.
CENtral Science
» News, notes, and musings from C&EN
Check out some of the recent posts from C&EN's blog, "C&ENtral Science"
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