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Analyzing Gulf Seafood
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Quote of the Week

"When we try to make new molecules, we can't predict whether one will be a safe one and one will be a bad one. We'd like to be able to do that."
LAWRENCE E. FRIED, CHEMIST, LAWRENCE LIVERMORE NATIONAL LABORATORY'S HIGH EXPLOSIVES APPLICATIONS FACILITYp. 32

July 18, 2011

In This Issue:

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October 24, 2011 Issue
October 17, 2011 Issue
October 10, 2011 Issue
October 3, 2011 Issue

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Highlights

Cover Story

Testing Gulf Seafood

After the oil spill, analytical protocols to assess contaminants in seafood found few problems, but the public and some scientists are not reassured. (pp. 12-16)

» Instrumentation: Firms Help Meet Demand For Equipment
Science & Technology

Preserving Plastic Art (Member Content)

Chemistry of polymer-based creations presents unique problems for conservators. (pp. 29-31)

Science & Technology

Examining Explosives (Member Content)

High Explosives Applications Facility researchers tackle science for national security. (pp. 32-34)

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Table of Contents

News Of The Week

A Cascade Of Natural Products p. 7

Total Synthesis: Organocatalyzed domino reactions speed assembly of multiple natural products.

A New Push Against HIV p. 8

Partnering: Merck, Sangamo, and NIH will join universities to combat HIV drug resistance.

Printing Single-Crystal Films p. 8

Electronics: Ink-jet method makes ordered semiconducting layers.

Lonza To Buy Arch Chemicals p. 9

Specialties: Acquisition will make Lonza a leader in the microbial control market.

Blaming DuPont p. 9

Safety board finds the company negligent in a series of accidents, one fatal, in 2010.

Improving Chemical Hazard Information p. 10

Risk Assessment: EPA documents to become more concise, describe scientific decisionmaking.

Spotlight On Nuclear Power p. 10

Review: U.S. nuclear plants need stronger safeguards for catastrophic events, panel says.

Silver Solos In Lemon Circuit p. 11

Materials Chemistry: Electrochemical cell based on same-metal electrodes is a first.

Drug Supply Oversight p. 11

Report cites measures that could mitigate risks in the global pharmaceutical supply chain.

Business

Algae Plans Bloom pp. 19-20 (Member Content)

From personal care to fish food, algae firms look for ways to make profits quickly.

Super Natural Cosmetic Potions pp. 21-22 (Member Content)

Advances in biotechnology enable a new generation of plant-derived ingredients.

Lifeline Skin Care pp. 21-22 (Member Content)

Biotech firm adds human cell extracts to cosmetics.

The Long War On Cancer p. 23 (Member Content)

Decades after the National Cancer Act, scientists are turning to information-rich, early-stage studies to advance oncology.

Business Concentrates pp. 17-18 (Member Content)

This Week Online

How Dirty Is The Yellow School Bus?

Air Pollution: Tailpipe controls on buses don't clear the air inside bus cabins.

Greening Mortar With Olive Waste

Construction Chemistry: Waste from olive oil production could shrink the building material's carbon footprint.

Zafgen's Obesity Drug Shows Promise

Guest blogger SeeArrOh, an industry chemist, guesses at how the drug may work in the body and describes some unusual chemical features of the molecule.

Algal Oil Spreads Its Wings

Fresh off his company's raising $227 million in its initial public offering, Solazyme executive Cameron Byers describes to C&EN the algae firm's strategies for being both environmentally and economically sustainable.

Government & Policy

Modernizing Toxicity Tests pp. 25-26 (Member Content)

EPA inches toward high-throughput in vitro assays to reduce cost, time of chemical safety assessments.

Government & Policy Concentrates p. 24 (Member Content)

Books

Taking The Measure Of Energy Options pp. 35-36

With a stiff dose of realism, book explores the complexity and enormity of global energy challenges.

People

Facebook

Social Networking And C&EN

Social Networking And C&EN

You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.

Science & Technology

Preserving Plastic Art pp. 29-31

Chemistry of polymer-based creations presents unique problems for conservators.

Examining Explosives pp. 32-34 (Member Content)

High Explosives Applications Facility researchers tackle science for national security.

Science & Technology Concentrates pp. 27-28

Meetings

2011 C&EN Calendar Web Exclusive

C&EN's latest list of meetings and events of interest to those in the chemical community.

Editor's Page

What Kind Of Nation? p. 3

The Departments

Letters pp. 4-5

Newscripts p. 40

Students Make Biodiesel, Padwa's Mobile Creations.

C&EN Archives

C&EN Archives

Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.

Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives

Environmental SCENE News

Fertilizer May Help Bacteria Slip Into Groundwater

Water Safety: High phosphate levels allow deadly microbes to pass through soil.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Sunlight Is An Effective Disinfectant

Public Health: Field work shows that a cheap water treatment method improves children's health.

House Takes Aim At Clean Air Act

Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.

Analytical SCENE News

New Method Isolates Membrane Proteins

Protein Purification: Technique separates proteins on a lipid bilayer.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Mapping Drugs In Human Tissue

Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.

Skeletons Come To Light

Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.

Analyzing Nuclear Processes

ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.

JACS Research In C&EN

Indole Changeup Yields Elusive Alkaloid

ACS Meeting News: Cyclization and nitrene insertion star in synthesis.

Prefab Synthesis Moves Ahead

Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.

Multiple Bradykinin States Revealed

The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.

Scaling Up The Axinellamines

A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.

A Revamped Vancomycin

Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.

CENtral Science

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


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