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December 18, 2006
Cover Story: Chemistry Highlights 2006
Top research advances of the year range from bio to nano.
December 11, 2006
Cover Story: Monolithic Chromatography
Nontraditional column materials improve separations of biomixtures.
December 4, 2006
Cover Story: Pharma Challenged
Market shifts and generic competition create dynamic environment for drug developers.
Mergers & Acquisitions
Megadeals wane, but consolidation continues.
Scripps Takes A New Approach
Florida campus brings drug discovery to the academic arena.
Anthrax Sleuthing
Science aids a nettlesome FBI criminal probe.
November 27, 2006
Cover Story: Thermo Fisher Scientific
Merger of two big players in scientific products creates lab industry giant.
Research Initiative
Walking In The Customers' Shoes.
November 20, 2006
Cover Story: Better Energy Through Chemistry
By supporting new energy creation techniques, specialty chemical companies are turning the oil and gas price run-up into a business opportunity.
Solar Revolution
The market for photovoltaics is expanding rapidly, and chemical companies are taking notice.
Fuels Of The Future
Chemistry and agriculture join to make a new generation of renewable fuels.
Start-up Firms Pursue Biofuels
Entrepreneurs invigorate search for economical biomass-based fuels.
Back To The Well
Chemistry targets cost-efficient extraction of oil and gas from mature reserves.
Microbial Methane Farming
With a boost from BASF, Luca is testing production of 'real-time' gas in mature wells.
Walking The Line
Protein motors march cargo to the extremities of a cell and drag apart DNA during mitosis.
November 13, 2006
Cover Story: Delivering RNA Interference
Developing siRNA therapeutics depends on synthetic delivery systems
November 6, 2006
Cover Story: Employment Looks A Little Better
The economy
shows signs of slowing, but firms may be hiring more chemists, engineers
Better Job Climate For New Graduates
For chemists, hiring in pharma picks up, and chemical engineers continue to be in high demand.
Strategies From Hiring Professionals
Salaries And Jobs
Salary prognosis for working chemists is for steady gains, but the job outlook is more uncertain.
Generation X Revisited
C&EN catches up with chemists profiled in 1995 to find out how their predictions panned out.
Entrepreneurial Spirit
Combine science and hard work with creativity, then get down to business.
Educating Entrepreneurs
A Patently Satisfying Career
Scientists-turned-lawyers offer tips on navigating a career in intellectual property law.
Making The Cover
Scientific art on journal covers raises visibility, but does it still serve
a purpose in the Internet age?
Research Misconduct
Federal agencies handle fabrication, falsification, and plagiarism allegations differently, but all take claims seriously.
October 30, 2006
Cover Story: Losing Their
Religion
Biotechs take a more "agnostic approach" to drug discovery by expanding into
small molecules
Polymers With Safe Amounts Of Copper
New polymerization techniques that reduce catalyst contamination of products
could find broad industrial use.
Chinese Industrial Parks Up The Ante
Managers of industrial development zones all over China learn to better
serve foreign and domestic companies.
October 23, 2006
Cover Story: Bacterial
Conversations
Using a chemical language, bacteria coordinate everything from infection
to plaque buildup
Chemistry For The Sake Of Art
For one Long Island artist, her studio is her laboratory.
October 16, 2006
Cover Story: Paints and
Coatings
Consolidation among paint material makers brings opportunities as well as
risks
Climate-Change Debate Shifts
Businesses and governments discuss top-down, bottom-up approaches to
averting irreversible dangerous changes.
October 9, 2006
Cover Story: Richard E. Smalley
C&EN marks the 10th
anniversary of the fullerene scientist's Nobel Prize and the first anniversary of the loss of this
civic-minded nanotechnology pioneer.
Multimedia: The World
According to Rick
October 9, 2006
Targeting
Telomerase
Researchers believe enzyme could be a nearly universal target for anticancer
drugs.
October 2, 2006
Cover Story: Mass
Spec Tackles Proteins
Mass spectrometry shines in applications from proteomics to
structural biology, but challenges remain.
October 2, 2006
Dead Zone
Task
force seeks advice on how to reduce and control Gulf of Mexico's low-oxygen zone.
September 25, 2006
Cover Story: Drugs To Fight Addictions
A better understanding of the mechanisms of drug and alcohol dependence is helping to further
development and use of pharmacotherapies against addictions.
September 18, 2006
Employment & Salary
Survey
Uptick in the job market for chemists in 2006 and a routine salary boost for those with jobs.
September 18, 2006
Cover Story: FDA Turns
100
Agency has come a long way in its first century, but serious challenges remain.
September 11, 2006
Cover Story: Information
Technology
Chemical companies are targeting IT investments to new applications of
existing systems, including logistics management.
September 11, 2006
Incredible
Colors
Scientific investigations unmask the secrets of 16th-century Venetian painters'
palettes.
September 4, 2006
Cover Story: Glycosylation Engineering
Controlling personalities tame wild sugars on proteins and natural products.
September 4, 2006
Road To Recovery
A year after the hurricanes, scientists and industry workers reflect on the impact on their work
and lives.
September 4, 2006
Squint Busters
Tool
builders are pushing optical microscope vision to single-molecule sharpness.
September 4, 2006
Academic Opportunities
Four-part
supplement explores ways in which students can individualize their chemistry and chemical
engineering programs.
August 28, 2006
Putting A Spin On
Electronics
Potential for advanced technologies drives search for room-temperature
magnetic semiconductors.
August 28, 2006
Cover Story: Renewable
Energy
Department of Energy's National Renewable Energy Laboratory stands out in the
spotlight created by President George W. Bush's backing of renewable energy research.
August 28, 2006
The Dope On Testosterone
Tests
Sound drug-testing procedures provide facts but don't determine the fate of
athletes caught cheating.
August 21, 2006
Cover Story: R&D
Takes Off In Shanghai
Chemical and drug companies rush to set up corporate laboratories, straining the availability of
qualified scientists.
August 14, 2006
Cover Story: Fine
Chemicals & Pharmaceuticals
Producers are taking advantage of enzymes to prepare
single-enantiomer compounds.
August 7, 2006
Cover Story: Battling
Breast Cancer
By targeting multiple HER-family receptors, small-molecule drugs could
fill the therapeutic gaps left by Herceptin.
August 7, 2006
Class Of 2005
Salaries & Jobs
Chemists' starting salaries are up a notch from 2004, but employment
scene remains below par.
July 31, 2006
Cover Story: Systems
Biology's Clinical Future
Although it now remains a research tool, systems biology is moving toward clinical applications,
including personalized medicine.
July 31, 2006
Hexacyclinol Debate Heats
Up
Second of two total syntheses casts doubt on earlier structure, synthesis.
Safer Antifreeze Bill Is Moving Fast
Congress is
on the verge of mandating a bitter additive, but chemical may not deter pets.
July 24, 2006
Cover Story: Global Top
50
Dow and BASF retain the top two spots, but the chemical businesses of three big oil
companies edge DuPont out of the top five of C&EN's annual survey.
July 24, 2006
Women In Industry
Women post gains in the
chemical company executive suite but not in the boardroom.
July 24, 2006
Malaria Control
Resurging use of the banned pesticide DDT to prevent malaria poses dilemma for health,
environment.
July 24, 2006
Open-Source Science
Online research communities aim to unite scientists worldwide to find cures for neglected
diseases.
July 24, 2006
Chemistry Grads Post Gains In
2005
New bachelor's and Ph.D. degrees increase, while growth in women's share
continues.
July 17, 2006
Cover Story: Epigenetics
Chemical
signposts on the genome's chromatin landscape turn genes on and off.
July 17, 2006
Chemical
Informatics
Informaticians help scientists cope with data overload.
July 17, 2006
Stock Indexes Fall In Second
Quarter
Shares of most chemical and pharmaceutical companies drop; shares of biotech
firms plunge.
July 10, 2006
Facts &
Figures
Chemical industry data for 2005 show continued improvements in sales and
earnings.
July 3, 2006
Elias A. Zerhouni
NIH director has steered agency through congressional inquiries and paltry budget increases with
bold actions to position agency for future.
June 26, 2006
Riding On Flat Panels
Materials suppliers are under pressure to raise output, but costs are rising, and rapid growth
doesn't always translate into high profits
Many Roads For CMP
As materials used to fabricate semiconductors proliferate, the planarization market is
fragmenting
Second Wind For OLEDS
Organic light-emitting diodes have made strong gains, but developers of the technology aren't
satisfied
June 19, 2006 - Special Issue
Pharma's Road Ahead
C&EN examines how the pharmaceutical industry, now on the defensive, is trying to win back
the public's confidence and enhance productivity.
Introduction: An Industry In
Transition
Web Profiles: The Human Face of
Pharma
June 12, 2006
Automotive Plastics
Automakers turn to plastics to reduce manufacturing costs and make cars lighter to increase fuel
economy.
June 5, 2006
Fabulous Fluorine
Having fluorine in
life sciences molecules brings desirable benefits, but the trick is getting it in place and making
sought-after building blocks.
June 5, 2006
Constructing Life Sciences Compounds
Fluorinated building blocks are increasingly used as the basis of valuable active molecules.
June 5, 2006
Guidelines For Assessing Risk
White House
proposal could impede broad range of government activities, agency representatives warn.
May 29, 2006
Dow Chemical
CEO Andrew Liveris
outlines challenges faced by his firm as well as those of the chemical industry.
May
29, 2006
Preventing Malaria
Insecticide-treated nets are playing an important role in fighting malaria in Africa, Southeast
Asia.
May 22, 2006
Halogenases
Scientists are learning the structural and mechanistic secrets of the exquisitely selective
enzymes that nature uses to install halogen atoms.
May 22, 2006
Chemical Earnings Decline
Slightly
Lower demand and rising costs continue to hamper results at 25 firms.
May 22, 2006
Strong Profit Gains For Big Drug
Producers
First-quarter results signal that cost-cutting measures are helping the bottom line.
May 22, 2006
A Steady Start For Biopharma
Companies
Larger biotech firms are starting to feel the same portfolio challenges as big
pharma companies.
May 22, 2006
Analytica Meets For 20th
Time
Attendance drops at biennial instrumentation trade show but still exceeds
organizers' expectations.
May 22, 2006
Finding A Niche In New
England
Outside Boston's biotech hub, New England pitches specialized positions and a
slower pace of life.
May 15, 2006
Metallography
Striking photographs reveal metallic microscapes beautiful enough to hang in an art gallery.
Top 50 Chemical Producers
Latest survey reflects
several mergers and another strong year for U.S. chemical makers.
Sex, Lies, and Title IX
Federal law
banning sex discrimination in schools may do as much for academics as it has for athletics.
Far From Safe
A rare
case of anthrax shows more is needed to protect citizens from infectious outbreaks, terror
attacks.
May 8, 2006
Personal Care
Synthetic polymers
improve the style, feel, and functionality of the latest cosmetics.
May 8, 2006
A Sweet Start For Inhalable Insulin
New approach to
delivering insulin scores a first for both diabetes and pulmonary drug delivery.
May 1, 2006
Nanotechnology
As they launch
commercial products, companies wrestle with health, safety, and other concerns and issues.
Vintage Chemistry
The color changes that occur as
wine ages are due to complex chemistry involving many compounds.
New Routes To Tamiflu Emerge
Research
groups in the U.S. and Japan develop routes that avoid shikimic acid.
April 24, 2006
Ionic
Liquids
Commercial applications are being realized for ionic liquids, but the new
product registration process could limit growth.
Kids And Cartoons
An animated molecular fantasy
from the Molecularium Project teaches about chemistry.
April 17, 2006
Oligonucleotides
After enduring a period
of skepticism, oligonucleotide-based antisense drugs appear to be regaining favor in the investment
community.
Nanotechnology In Food And Agriculture
Database
finds diverse themes and predominantly basic research in federally funded R&D.
Planning Nanotech From The Ground
Up
Scientists aim to design and produce safe, high-performance nanomaterials 'right the
first time'.
What's That Stuff?
Marshmallow
Gelatin has largely replaced the spongy confection's namesake, a plant-root
ingredient.
Chemical Biology: Adventure
Awaits
In the interdisciplinary field, researchers are defined more by their mind-sets
than skill sets.
April 10, 2006
Pharma Outsourcing
The
search for a cure for cancer unites three partnerships between a drug developer and a pharmaceutical
chemical company
Double Play
A
successful contract with a productive drug developer leads to a second piece of business.
Speed Limit
A pharmaceutical
company and its chemistry partner scramble when a drug is fast-tracked.
Crossover
The effort to
develop a small-molecule follow-on leads to a contract between neighboring firms.
April 10, 2006
Chemistry Action
Video game aspires to increase students' confidence in studying chemistry.
April 3, 2006
Better Than Ever At Pittcon
2006
Attendance may be slipping, but enthusiasm for new and innovative analytical
instrumentation has not waned
Pittcon, Other Trade Shows May Be
Declining In Importance For Small Firms
Shimadzu Exhibits 50-Year-Old
Gas Chromatograph At Pittcon
Analyzing Vaccines
Complicated mixtures that make up therapeutics vaccines provide diverse analytical challenges
Bioimaging With Mass
Spectrometry
High-resolution maps of molecular species distributions are poised to
benefit biology, medicine
Private Eye In The Lab
New tools and analytical methods aid chemists in forensic investigations
Multitasking Cells
Experiments in microfluidic devices suggest surprising roles for red blood cells
Building Bridges
Coalition advocates for nontraditional grant review mechanism to foster deep innovation
Chinese Instrument Market
Warms Up
Chinese instrument industry lags behind the world's but has tremendous room for
growth
New & Notable
At Pittcon 2006
Instrumentation and More
All That Glows
Bioluminescence provides
practical applications while still remaining a mystery.
Industrial Biotech Gains Momentum
Growth of commercial enzyme-mediated processes points to the future of the chemical industry.
March 27, 2006
Body, Heal Thyself
After false starts, cancer
immunotherapies tiptoe toward commercialization.
2006 Priestley Medalist
Former
ACS president Paul S. Anderson is honored for more than 40 years of accomplishments in the
pharmaceutical industry.
Molecular Pas De Deux
Photoreactive host
molecule mechanically twists guest compound.
March 20, 2006
Petrochemicals Keep Up The Pace
Even with a few
setbacks, petrochemical makers had a decent year in 2005 and are optimistic about 2006.
Science In India
Aided by the return of expatriates and ample money for R&D, India is building its drug
discovery capabilities, fostering interdisciplinary science, and developing a vibrant postdoc
culture.
Building R&D For Drug
Discovery
Seasoned expatriates trickle back to help Indian pharmaceutical firms push
into discovery research
Collaboration
Indian
Pharma Bets On Links With Academia And Government
Bridges Wait To Be
Built
India struggles to foster interdisciplinary science
Keeping Postdocs At Home In
India
A vibrant postdoc culture could invigorate India's research climate, but
recruiting remains difficult
A World Apart
Divergence of undergrad education and scientific research in India has been detrimental to
both
A Funding Evolution
Some of India's scientists find research dollars easier than ever to obtain, but inequities
remain
Silent Chemistry
Programs help deaf students overcome challenges to becoming molecular scientists.
Sprites Trigger Sky-High Chemistry
High-altitude lightning is visually stunning, but is it also a player in atmospheric
chemistry?.
March 13, 2006
Arden L. Bement Jr.
NSF director
shares excitement for foundation's future, enthusiasm for ongoing research, and insights into
science and technology policy issues.
Back To
Business
Custom chemical manufacturers showed renewed faith in their industry at this
year's Informex.
Nisin Engineered In Test Tube
Biosynthetic
route may open up access to analogs of potent antibiotic.
What's That Stuff? Motor Oil
Lubricant keeps car engines from clanging apart, sparks debates on how often it should be
changed.
March 6, 2006
Big Pharma-Biotech Partnerships
Renewed interest in early-stage alliances helps to create a more farsighted approach to deal
making.
Nobel Laureate Is Accused Of Nazi
Collaboration
Dutch university strips the name of Peter J. W. Debye from one of its
scientific institutes.
February 27, 2006
A Magnet For Talent
Singapore prepares to move up the R&D value chain by building a research infrastructure with
both foreign and homegrown talent
An Unlikely Center For
Pharmaceuticals
India has skilled labor and China has raw materials, but big drug companies prefer Singapore
Educational Alliance Takes
Next Step
Singaporean universities and MIT launch second phase of their education and
research partnership
Chemical Earnings In Fourth
Quarter
Results were hard hit by effects of hurricanes; DuPont was a big factor in poor
growth.
Safely Managing Chemicals
Global agreement aimed at protecting health, environment could also affect trade disputes.
February 24, 2006
Investing In
Nanotechnology
Funding for the discipline is on the rise, but returns remain small.
February 20, 2006
Electrochemistry
Researchers
are using electrochemical techniques to observe the chemistry of neurons in the human brain.
2007 R&D Budget Lacks Balance
Sizable
funding increases in a number of research areas are negated by cuts in other programs.
Vaccines Give Pharma Employment A Boost
More opportunities for chemists are likely to materialize as the field grows.
February 13, 2006
Custom Chemicals
As the
global paradigm for the custom manufacturing business continuesto shift, providers struggle to
differentiate themselves from the competition
Europe Adopts GMP
Regulations
Directive on Good Manufacturing Practices could help level the competitive
playing field
Fine Chemicals Group Offers
Commonsense Steps
EFCG Reaches
Milestones After First Year
Outlook Remains Cautious
For 2006
Jaded industry participants are wary about predicting an upturn for custom
chemicals
February 6, 2006
Chemical Spending
Firms plan large
boost in capital investments but only a modest increase in R&D.
The Secret Life Of Plant Crystals
Microscopic view of plant tissue reveals a hidden world of calcium oxalate crystals of diverse
shapes.
What's That Stuff? Henna
Dye derived from green henna leaves is used to decorate the body with intricate designs.
January 30, 2006
Soaps &
Detergents
Specialty chemical makers seek business both with cleaning product innovators and the companies
that follow them.
Automatic Dishwashing
Technology At Heart Of New Product.
Surfactant Firms End A Tough
Year
Restructuring steps are taken to counteract challenges in a competitive
industry.
Soap &
Detergent Association
Trade Group Confronts Emerging Chemical Regulations.
Crystal Ball On The Environment
Detective
work and expertise are used to evaluate environmental contaminants of emerging concern.
Peptide Synthesis Reinvented
Versatile
amide-forming reaction could transform field of biomolecular synthesis.
January 23, 2006
Congressional
Outlook
Congress will reconvene to deal with legislation on gas and oil drilling,
chemical plant security, tort reform, clean air legislation, and holding down federal spending.
Flavor Chemistry
For those with
analytical skills, job prospects in the food and beverage industries continue to look good.
January 16, 2006
Glassblowing
Trade may be in decline
because of changing technologies and medical advances, but glassblowers still play a pivotal
role.
Stock Indexes Mixed
Chemicals and biotech
improve in fourth quarter, but pharmaceuticals decline slightly.
January 9, 2006
World Chemical Outlook
United States
The
chemical industry enters 2006 with many of the concerns it had in 2005.
Canada
Profitability
continued in 2005, but long-term outlook for new petrochemical investment isn't good.
Latin America
The region
is enjoying commercial success and hatching big plans for future growth.
Europe
Chemical industry braces for a new regulatory regime while exploiting a pickup in output.
Asia-Pacific
Economies are performing strongly, but concerns linger about long-term impact of high oil
prices.
January 2, 2006
President's Message
ACS President E.
Ann Nalley addresses the future of the chemical enterprise.
This page updated October 16, 2006
December 18, 2006
Cover Story: Chemistry Highlights 2006
Top research advances of the year range from bio to nano.
December 11, 2006
Cover Story: Monolithic Chromatography
Nontraditional column materials improve separations of biomixtures.
December 4, 2006
Cover Story: Pharma Challenged
Market shifts and generic competition create dynamic environment for drug developers.
Mergers & Acquisitions
Megadeals wane, but consolidation continues.
Scripps Takes A New Approach
Florida campus brings drug discovery to the academic arena.
Anthrax Sleuthing
Science aids a nettlesome FBI criminal probe.
November 27, 2006
Cover Story: Thermo Fisher Scientific
Merger of two big players in scientific products creates lab industry giant.
Research Initiative
Walking In The Customers' Shoes.
November 20, 2006
Cover Story: Better Energy Through Chemistry
By supporting new energy creation techniques, specialty chemical companies are turning the oil and gas price run-up into a business opportunity.
Solar Revolution
The market for photovoltaics is expanding rapidly, and chemical companies are taking notice.
Fuels Of The Future
Chemistry and agriculture join to make a new generation of renewable fuels.
Start-up Firms Pursue Biofuels
Entrepreneurs invigorate search for economical biomass-based fuels.
Back To The Well
Chemistry targets cost-efficient extraction of oil and gas from mature reserves.
Microbial Methane Farming
With a boost from BASF, Luca is testing production of 'real-time' gas in mature wells.
Walking The Line
Protein motors march cargo to the extremities of a cell and drag apart DNA during mitosis.
November 13, 2006
Cover Story: Delivering RNA Interference
Developing siRNA therapeutics depends on synthetic delivery systems
November 6, 2006
Cover Story: Employment Looks A Little Better
The economy shows signs of slowing, but firms may be hiring more chemists, engineers
Better Job Climate For New Graduates
For chemists, hiring in pharma picks up, and chemical engineers continue to be in high demand.
Strategies From Hiring Professionals
Salaries And Jobs
Salary prognosis for working chemists is for steady gains, but the job outlook is more uncertain.
Generation X Revisited
C&EN catches up with chemists profiled in 1995 to find out how their predictions panned out.
Entrepreneurial Spirit
Combine science and hard work with creativity, then get down to business.
Educating Entrepreneurs
A Patently Satisfying Career
Scientists-turned-lawyers offer tips on navigating a career in intellectual property law.
Making The Cover
Scientific art on journal covers raises visibility, but does it still serve a purpose in the Internet age?
Research Misconduct
Federal agencies handle fabrication, falsification, and plagiarism allegations differently, but all take claims seriously.
October 30, 2006
Cover Story: Losing Their Religion
Biotechs take a more "agnostic approach" to drug discovery by expanding into small molecules
Polymers With Safe Amounts Of Copper
New polymerization techniques that reduce catalyst contamination of products could find broad industrial use.
Chinese Industrial Parks Up The Ante
Managers of industrial development zones all over China learn to better serve foreign and domestic companies.
October 23, 2006
Cover Story: Bacterial Conversations
Using a chemical language, bacteria coordinate everything from infection to plaque buildup
Chemistry For The Sake Of Art
For one Long Island artist, her studio is her laboratory.
October 16, 2006
Cover Story: Paints and Coatings
Consolidation among paint material makers brings opportunities as well as risks
Climate-Change Debate Shifts
Businesses and governments discuss top-down, bottom-up approaches to averting irreversible dangerous changes.
October 9, 2006
Cover Story: Richard E. Smalley
C&EN marks the 10th anniversary of the fullerene scientist's Nobel Prize and the first anniversary of the loss of this civic-minded nanotechnology pioneer.
Multimedia: The World According to Rick
October 9, 2006
Targeting Telomerase
Researchers believe enzyme could be a nearly universal target for anticancer drugs.
October 2, 2006
Cover Story: Mass Spec Tackles Proteins
Mass spectrometry shines in applications from proteomics to structural biology, but challenges remain.
October 2, 2006
Dead Zone
Task force seeks advice on how to reduce and control Gulf of Mexico's low-oxygen zone.
September 25, 2006
Cover Story: Drugs To Fight Addictions
A better understanding of the mechanisms of drug and alcohol dependence is helping to further development and use of pharmacotherapies against addictions.
September 18, 2006
Employment & Salary Survey
Uptick in the job market for chemists in 2006 and a routine salary boost for those with jobs.
September 18, 2006
Cover Story: FDA Turns 100
Agency has come a long way in its first century, but serious challenges remain.
September 11, 2006
Cover Story: Information Technology
Chemical companies are targeting IT investments to new applications of existing systems, including logistics management.
September 11, 2006
Incredible Colors
Scientific investigations unmask the secrets of 16th-century Venetian painters' palettes.
September 4, 2006
Cover Story: Glycosylation Engineering
Controlling personalities tame wild sugars on proteins and natural products.
September 4, 2006
Road To Recovery
A year after the hurricanes, scientists and industry workers reflect on the impact on their work and lives.
September 4, 2006
Squint Busters
Tool builders are pushing optical microscope vision to single-molecule sharpness.
September 4, 2006
Academic Opportunities
Four-part supplement explores ways in which students can individualize their chemistry and chemical engineering programs.
August 28, 2006
Putting A Spin On Electronics
Potential for advanced technologies drives search for room-temperature magnetic semiconductors.
August 28, 2006
Cover Story: Renewable Energy
Department of Energy's National Renewable Energy Laboratory stands out in the spotlight created by President George W. Bush's backing of renewable energy research.
August 28, 2006
The Dope On Testosterone Tests
Sound drug-testing procedures provide facts but don't determine the fate of athletes caught cheating.
August 21, 2006
Cover Story: R&D Takes Off In Shanghai
Chemical and drug companies rush to set up corporate laboratories, straining the availability of qualified scientists.
August 14, 2006
Cover Story: Fine Chemicals & Pharmaceuticals
Producers are taking advantage of enzymes to prepare single-enantiomer compounds.
August 7, 2006
Cover Story: Battling Breast Cancer
By targeting multiple HER-family receptors, small-molecule drugs could fill the therapeutic gaps left by Herceptin.
August 7, 2006
Class Of 2005 Salaries & Jobs
Chemists' starting salaries are up a notch from 2004, but employment scene remains below par.
July 31, 2006
Cover Story: Systems Biology's Clinical Future
Although it now remains a research tool, systems biology is moving toward clinical applications, including personalized medicine.
July 31, 2006
Hexacyclinol Debate Heats Up
Second of two total syntheses casts doubt on earlier structure, synthesis.
Safer Antifreeze Bill Is Moving Fast
Congress is on the verge of mandating a bitter additive, but chemical may not deter pets.
July 24, 2006
Cover Story: Global Top 50
Dow and BASF retain the top two spots, but the chemical businesses of three big oil companies edge DuPont out of the top five of C&EN's annual survey.
July 24, 2006
Women In Industry
Women post gains in the chemical company executive suite but not in the boardroom.
July 24, 2006
Malaria Control
Resurging use of the banned pesticide DDT to prevent malaria poses dilemma for health, environment.
July 24, 2006
Open-Source Science
Online research communities aim to unite scientists worldwide to find cures for neglected diseases.
July 24, 2006
Chemistry Grads Post Gains In 2005
New bachelor's and Ph.D. degrees increase, while growth in women's share continues.
July 17, 2006
Cover Story: Epigenetics
Chemical signposts on the genome's chromatin landscape turn genes on and off.
July 17, 2006
Chemical Informatics
Informaticians help scientists cope with data overload.
July 17, 2006
Stock Indexes Fall In Second Quarter
Shares of most chemical and pharmaceutical companies drop; shares of biotech firms plunge.
July 10, 2006
Facts & Figures
Chemical industry data for 2005 show continued improvements in sales and earnings.
July 3, 2006
Elias A. Zerhouni
NIH director has steered agency through congressional inquiries and paltry budget increases with bold actions to position agency for future.
June 26, 2006
Riding On Flat Panels
Materials suppliers are under pressure to raise output, but costs are rising, and rapid growth doesn't always translate into high profits
Many Roads For CMP
As materials used to fabricate semiconductors proliferate, the planarization market is fragmenting
Second Wind For OLEDS
Organic light-emitting diodes have made strong gains, but developers of the technology aren't satisfied
June 19, 2006 - Special Issue
Pharma's Road Ahead
C&EN examines how the pharmaceutical industry, now on the defensive, is trying to win back the public's confidence and enhance productivity.
Introduction: An Industry In Transition
Web Profiles: The Human Face of Pharma
June 12, 2006
Automotive Plastics
Automakers turn to plastics to reduce manufacturing costs and make cars lighter to increase fuel economy.
June 5, 2006
Fabulous Fluorine
Having fluorine in life sciences molecules brings desirable benefits, but the trick is getting it in place and making sought-after building blocks.
June 5, 2006
Constructing Life Sciences Compounds
Fluorinated building blocks are increasingly used as the basis of valuable active molecules.
June 5, 2006
Guidelines For Assessing Risk
White House proposal could impede broad range of government activities, agency representatives warn.
May 29, 2006
Dow Chemical
CEO Andrew Liveris outlines challenges faced by his firm as well as those of the chemical industry.
May 29, 2006
Preventing Malaria
Insecticide-treated nets are playing an important role in fighting malaria in Africa, Southeast Asia.
May 22, 2006
Halogenases
Scientists are learning the structural and mechanistic secrets of the exquisitely selective enzymes that nature uses to install halogen atoms.
May 22, 2006
Chemical Earnings Decline Slightly
Lower demand and rising costs continue to hamper results at 25 firms.
May 22, 2006
Strong Profit Gains For Big Drug Producers
First-quarter results signal that cost-cutting measures are helping the bottom line.
May 22, 2006
A Steady Start For Biopharma Companies
Larger biotech firms are starting to feel the same portfolio challenges as big pharma companies.
May 22, 2006
Analytica Meets For 20th Time
Attendance drops at biennial instrumentation trade show but still exceeds organizers' expectations.
May 22, 2006
Finding A Niche In New England
Outside Boston's biotech hub, New England pitches specialized positions and a slower pace of life.
May 15, 2006
Metallography
Striking photographs reveal metallic microscapes beautiful enough to hang in an art gallery.
Top 50 Chemical Producers
Latest survey reflects several mergers and another strong year for U.S. chemical makers.
Sex, Lies, and Title IX
Federal law banning sex discrimination in schools may do as much for academics as it has for athletics.
Far From Safe
A rare case of anthrax shows more is needed to protect citizens from infectious outbreaks, terror attacks.
May 8, 2006
Personal Care
Synthetic polymers improve the style, feel, and functionality of the latest cosmetics.
May 8, 2006
A Sweet Start For Inhalable Insulin
New approach to delivering insulin scores a first for both diabetes and pulmonary drug delivery.
May 1, 2006
Nanotechnology
As they launch commercial products, companies wrestle with health, safety, and other concerns and issues.
Vintage Chemistry
The color changes that occur as wine ages are due to complex chemistry involving many compounds.
New Routes To Tamiflu Emerge
Research groups in the U.S. and Japan develop routes that avoid shikimic acid.
April 24, 2006
Ionic Liquids
Commercial applications are being realized for ionic liquids, but the new product registration process could limit growth.
Kids And Cartoons
An animated molecular fantasy from the Molecularium Project teaches about chemistry.
April 17, 2006
Oligonucleotides
After enduring a period of skepticism, oligonucleotide-based antisense drugs appear to be regaining favor in the investment community.
Nanotechnology In Food And Agriculture
Database finds diverse themes and predominantly basic research in federally funded R&D.
Planning Nanotech From The Ground Up
Scientists aim to design and produce safe, high-performance nanomaterials 'right the first time'.
What's That Stuff? Marshmallow
Gelatin has largely replaced the spongy confection's namesake, a plant-root ingredient.
Chemical Biology: Adventure Awaits
In the interdisciplinary field, researchers are defined more by their mind-sets than skill sets.
April 10, 2006
Pharma Outsourcing
The search for a cure for cancer unites three partnerships between a drug developer and a pharmaceutical chemical company
Double Play
A successful contract with a productive drug developer leads to a second piece of business.
Speed Limit
A pharmaceutical company and its chemistry partner scramble when a drug is fast-tracked.
Crossover
The effort to develop a small-molecule follow-on leads to a contract between neighboring firms.
April 10, 2006
Chemistry Action
Video game aspires to increase students' confidence in studying chemistry.
April 3, 2006
Better Than Ever At Pittcon 2006
Attendance may be slipping, but enthusiasm for new and innovative analytical instrumentation has not waned
Pittcon, Other Trade Shows May Be Declining In Importance For Small Firms
Shimadzu Exhibits 50-Year-Old Gas Chromatograph At Pittcon
Analyzing Vaccines
Complicated mixtures that make up therapeutics vaccines provide diverse analytical challenges
Bioimaging With Mass Spectrometry
High-resolution maps of molecular species distributions are poised to benefit biology, medicine
Private Eye In The Lab
New tools and analytical methods aid chemists in forensic investigations
Multitasking Cells
Experiments in microfluidic devices suggest surprising roles for red blood cells
Building Bridges
Coalition advocates for nontraditional grant review mechanism to foster deep innovation
Chinese Instrument Market Warms Up
Chinese instrument industry lags behind the world's but has tremendous room for growth
New & Notable At Pittcon 2006
Instrumentation and More
All That Glows
Bioluminescence provides practical applications while still remaining a mystery.
Industrial Biotech Gains Momentum
Growth of commercial enzyme-mediated processes points to the future of the chemical industry.
March 27, 2006
Body, Heal Thyself
After false starts, cancer immunotherapies tiptoe toward commercialization.
2006 Priestley Medalist
Former ACS president Paul S. Anderson is honored for more than 40 years of accomplishments in the pharmaceutical industry.
Molecular Pas De Deux
Photoreactive host molecule mechanically twists guest compound.
March 20, 2006
Petrochemicals Keep Up The Pace
Even with a few setbacks, petrochemical makers had a decent year in 2005 and are optimistic about 2006.
Science In India
Aided by the return of expatriates and ample money for R&D, India is building its drug discovery capabilities, fostering interdisciplinary science, and developing a vibrant postdoc culture.
Building R&D For Drug Discovery
Seasoned expatriates trickle back to help Indian pharmaceutical firms push into discovery research
Collaboration
Indian Pharma Bets On Links With Academia And Government
Bridges Wait To Be Built
India struggles to foster interdisciplinary science
Keeping Postdocs At Home In India
A vibrant postdoc culture could invigorate India's research climate, but recruiting remains difficult
A World Apart
Divergence of undergrad education and scientific research in India has been detrimental to both
A Funding Evolution
Some of India's scientists find research dollars easier than ever to obtain, but inequities remain
Silent Chemistry
Programs help deaf students overcome challenges to becoming molecular scientists.
Sprites Trigger Sky-High Chemistry
High-altitude lightning is visually stunning, but is it also a player in atmospheric chemistry?.
March 13, 2006
Arden L. Bement Jr.
NSF director shares excitement for foundation's future, enthusiasm for ongoing research, and insights into science and technology policy issues.
Back To Business
Custom chemical manufacturers showed renewed faith in their industry at this year's Informex.
Nisin Engineered In Test Tube
Biosynthetic route may open up access to analogs of potent antibiotic.
What's That Stuff? Motor Oil
Lubricant keeps car engines from clanging apart, sparks debates on how often it should be changed.
March 6, 2006
Big Pharma-Biotech Partnerships
Renewed interest in early-stage alliances helps to create a more farsighted approach to deal making.
Nobel Laureate Is Accused Of Nazi Collaboration
Dutch university strips the name of Peter J. W. Debye from one of its scientific institutes.
February 27, 2006
A Magnet For Talent
Singapore prepares to move up the R&D value chain by building a research infrastructure with both foreign and homegrown talent
An Unlikely Center For Pharmaceuticals
India has skilled labor and China has raw materials, but big drug companies prefer Singapore
Educational Alliance Takes Next Step
Singaporean universities and MIT launch second phase of their education and research partnership
Chemical Earnings In Fourth Quarter
Results were hard hit by effects of hurricanes; DuPont was a big factor in poor growth.
Safely Managing Chemicals
Global agreement aimed at protecting health, environment could also affect trade disputes.
February 24, 2006
Investing In Nanotechnology
Funding for the discipline is on the rise, but returns remain small.
February 20, 2006
Electrochemistry
Researchers are using electrochemical techniques to observe the chemistry of neurons in the human brain.
2007 R&D Budget Lacks Balance
Sizable funding increases in a number of research areas are negated by cuts in other programs.
Vaccines Give Pharma Employment A Boost
More opportunities for chemists are likely to materialize as the field grows.
February 13, 2006
Custom Chemicals
As the global paradigm for the custom manufacturing business continuesto shift, providers struggle to differentiate themselves from the competition
Europe Adopts GMP Regulations
Directive on Good Manufacturing Practices could help level the competitive playing field
Fine Chemicals Group Offers Commonsense Steps
EFCG Reaches Milestones After First Year
Outlook Remains Cautious For 2006
Jaded industry participants are wary about predicting an upturn for custom chemicals
February 6, 2006
Chemical Spending
Firms plan large boost in capital investments but only a modest increase in R&D.
The Secret Life Of Plant Crystals
Microscopic view of plant tissue reveals a hidden world of calcium oxalate crystals of diverse shapes.
What's That Stuff? Henna
Dye derived from green henna leaves is used to decorate the body with intricate designs.
January 30, 2006
Soaps & Detergents
Specialty chemical makers seek business both with cleaning product innovators and the companies that follow them.
Automatic Dishwashing
Technology At Heart Of New Product.
Surfactant Firms End A Tough Year
Restructuring steps are taken to counteract challenges in a competitive industry.
Soap & Detergent Association
Trade Group Confronts Emerging Chemical Regulations.
Crystal Ball On The Environment
Detective work and expertise are used to evaluate environmental contaminants of emerging concern.
Peptide Synthesis Reinvented
Versatile amide-forming reaction could transform field of biomolecular synthesis.
January 23, 2006
Congressional Outlook
Congress will reconvene to deal with legislation on gas and oil drilling, chemical plant security, tort reform, clean air legislation, and holding down federal spending.
Flavor Chemistry
For those with analytical skills, job prospects in the food and beverage industries continue to look good.
January 16, 2006
Glassblowing
Trade may be in decline because of changing technologies and medical advances, but glassblowers still play a pivotal role.
Stock Indexes Mixed
Chemicals and biotech improve in fourth quarter, but pharmaceuticals decline slightly.
January 9, 2006
World Chemical Outlook
United States
The chemical industry enters 2006 with many of the concerns it had in 2005.
Canada
Profitability continued in 2005, but long-term outlook for new petrochemical investment isn't good.
Latin America
The region is enjoying commercial success and hatching big plans for future growth.
Europe
Chemical industry braces for a new regulatory regime while exploiting a pickup in output.
Asia-Pacific
Economies are performing strongly, but concerns linger about long-term impact of high oil prices.
January 2, 2006
President's Message
ACS President E. Ann Nalley addresses the future of the chemical enterprise.
This page updated October 16, 2006