Modern Drug Discovery ACS Publications
August 2002 From Concept to Development
MDD home
Volume 5, Issue 8
Article Indexes
Author Indexes
 
 

 

Features

Grabbing the golden bead (445 KB)
by Viktor Krchnak and Colin Dalton
Medicinal chemists reap the benefits of solid-split-and-pool combichem techniques.

 
HIV—The biography of a killer (976 KB)
by Mark S. Lesney
As simple measures of attack prove inadequate and hopes for a vaccine diminish, researchers focus on the cycle of the whole disease for new drug targets.

Departments

Content in Context
The black box (149 KB)
by James F. Ryan

News in Brief
HIV drug adversity
Sweet discovery for insulin resistance (166 KB)
Proteins: Bone-bound
Waste makes paste? (147 KB)
Chat lines and escort services
Forgive and be well (179 KB)
The doctor is in—for e-patients
Old drug, new benefits (155 KB)

Clinical Trials Track
Rules and ethics betrayed
(254 KB)
by Cullen T. Vogelson
Numerous safeguards exist to protect subjects enrolled in medical research studies, but are they enough?

Patents and Property
The drug name game (253 KB)
by Tracy Durkin and Julie Shirk
Pharmaceutical companies must get nomenclature approved by the FDA and the U.S. Patent and Trademark Office.

 

Patents and Property
The drug name game
(253 KB)
by Tracy Durkin and Julie Shirk
Pharmaceutical companies must get nomenclature approved by the FDA and the U.S. Patent and Trademark Office.

The Tool Box
Enzymes in organic synthesis
(240 KB)
by Grace DeSantis
To simplify these reactions, researchers are using a new class of tools to make chiral drugs.

The Time Line
Confronting “the strangler”
(270 KB)
by Christopher S. W. Koehler
From ancient Greece to the 21st century, diphtheria has plagued humanity, continuing today despite effective vaccines.

Ready to Read (202 KB)
Big Shot: Passion, Politics, and the Struggle for an AIDS Vaccine
Reviewed by Richard A. Pizzi

New Product Notes (346 KB)

Diseases and Disorder
Obsessive–compulsive disorder (167 KB)
by Erik Whitemon

 

ISSN 1532-4486