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Drug Development
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Quote of the Week

"EPA has its foot firmly on the throat of our economic recovery."
REP. FRED UPTON (R-MICH.)p. 26

January 17, 2011

In This Issue:

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October 24, 2011 Issue
October 17, 2011 Issue
October 10, 2011 Issue
October 3, 2011 Issue

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Highlights

Cover Story

Technology Renews A Basic Approach

Dried blood spots offer advantages, but also challenges, for pharmaceutical analysis. (pp. 13-17)

Business

Ethylene From Methane (Member Content)

Researchers take a new look at an old problem. (pp. 20-21)

Government & Policy

Congressional Outlook For 2011 (Member Content)

Energy, environment, and drug safety oversight hearings are likely to dominate first session. (pp. 26-31)

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Table of Contents

News Of The Week

DuPont Snaps Up Danisco p. 7

Industrial Biotech: $6.3 billion deal will strengthen DuPont's business in alternative fuels and food ingredients.

CO2 Helps Crystals Change Shape p. 8

Pharmaceutical Chemistry: Polymorphs convert under mild conditions.

EPA Acts On Fluoride p. 8

Regulations: Agency moves to reduce children's exposure to fluoride.

Firms, Feds Blamed For Gulf Oil Spill p. 9

Investigation: Government panel faults lax oversight, poor industry practices for disaster.

Merck Will Revamp Former Schering-Plough Headquarters. p. 9

Pharmaceuticals: Shift of biotech research to Kenilworth will result in 580 manufacturing job cuts.

A New Feat For Gold Catalysts p. 10

Catalysis: Gold-palladium nanoparticles exclusively transform primary C–H bonds.

Europe's Dioxin Scare Widens p. 10

Food Safety: German eggs, poultry, pork are under scrutiny for contamination.

Drug Companies Poised For Growth p. 11

Outlook: Firms at J. P. Morgan conference shift conversation from restructuring to results.

Hungary's Red Mud Catastrophe Packs A Punch On Plants p. 11

Industrial Accident: Sodium salt, more than heavy metals, from the bauxite reservoir spill may hurt crops.

Business

Ethylene From Methane pp. 20-21 (Member Content)

Researchers take a new look at an old problem.

Concentrating On Chemistry p. 23 (Member Content)

Contract pharmaceutical chemicals maker CiVentiChem enjoys steady growth in the U.S. and India.

Business Concentrates pp. 18-19 (Member Content)

Books

Sowing Seeds Of Doubt pp. 38-39

How some scientists can twist the facts to suit ends other than scientific truth.

Awards

Awards: January 17 pp. 44-50 (Member Content)

Government & Policy

Congressional Outlook For 2011 pp. 26-31 (Member Content)

Energy, environment, and drug safety oversight hearings are likely to dominate first session.

Government & Policy Concentrates p. 24 (Member Content)

  • Bayer Vows To Drop Methyl Isocyanate
  • The Bayer CropScience pesticide plant near Charleston, W.Va., will phase out production of methyl isocyanate (MIC) over the next 18 months...
  • Army Destroys Chemical Munitions At Anniston
  • The Anniston Chemical Agent Disposal Facility in Alabama has completed the elimination of mustard-agent-filled mortars stored at the installation...
  • EPA Defers Permits For Biomass Burning
  • Electricity generators that burn biomass, such as wood, will get a partial three-year reprieve from new regulatory requirements for large industrial facilities that emit greenhouse gases....
  • NIH Urged To Address More Conflicts
  • Institutions that receive NIH funding should be required to develop policies and procedures that address institutional financial conflicts of interest...
  • Senators Clarify Biosimilars Law
  • In a Jan. 7 letter to FDA Commissioner Margaret A. Hamburg, Sens. Michael B. Enzi (R-Wyo.), Kay R. Hagan (D-N.C.), Orrin G. Hatch (R-Utah), and John F. Kerry (D-Mass.) reminded...

ACS Comment

The Power Of Collaboration p. 40 (Member Content)

ACS News

ACS Board Elects Chair, Executive Committee Members pp. 42-43 (Member Content)

Leaders elected and strategic issues considered at December meeting of society's top governance body.

Facebook

Social Networking And C&EN

Social Networking And C&EN

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Science & Technology

IR Spectroscopy With Superbright Light pp. 34-35 (Member Content)

Pacifichem News: Synchrotron beams enable spectroscopists to observe the biochemistry of cells.

Cataracts Via Protein Interactions pp. 36 (Member Content)

Experimental, theoretical tools reveal a new route to the eye disease.

Science & Technology Concentrates pp. 32-33 (Member Content)

Meetings

Editor's Page

Welcome To IYC 2011 p. 3

The Departments

Letters pp. 4-6

Newscripts p. 40

Desert Downpours, Swimming Giraffes, Chemical-Free Smells

This Week Online

C&EN Archives

C&EN Archives

Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.

Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives

Environmental SCENE News

Fertilizer May Help Bacteria Slip Into Groundwater

Water Safety: High phosphate levels allow deadly microbes to pass through soil.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Sunlight Is An Effective Disinfectant

Public Health: Field work shows that a cheap water treatment method improves children's health.

House Takes Aim At Clean Air Act

Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.

Analytical SCENE News

New Method Isolates Membrane Proteins

Protein Purification: Technique separates proteins on a lipid bilayer.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Mapping Drugs In Human Tissue

Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.

Skeletons Come To Light

Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.

Analyzing Nuclear Processes

ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.

JACS Research In C&EN

Indole Changeup Yields Elusive Alkaloid

ACS Meeting News: Cyclization and nitrene insertion star in synthesis.

Prefab Synthesis Moves Ahead

Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.

Multiple Bradykinin States Revealed

The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.

Scaling Up The Axinellamines

A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.

A Revamped Vancomycin

Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.

CENtral Science

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


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