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Quote of the Week
"A lot of people are in favor of innovative funding models—as long as you continue to fund their research."
ALAN GUTTMACHER, DIRECTOR, NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT – p. 29
January 24, 2011
In This Issue:
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Highlights
Cover Story
Phosphate-Free Formulas
New laws prompt makers of automatic dishwasher detergents to frantically seek effective replacements for phosphates. (pp. 12-17)
» Ecover Succeeds Without Phosphates—Or Petrochemicals
Government & Policy
Transforming Deep-Sea Drilling (Member Content)
BP spill commission calls for sweeping changes in industry practices, federal regulation. (pp. 24-26)
Science & Technology
Shotgun Approach To Drugs (Member Content)
Pacifichem News: Polypharmacology gives rise to drugs with multiple targets. (pp. 32-33)
Table of Contents
News Of The Week
Bayer Accused Of Skirting Safety p. 7
Investigation: Rush to production caused plant explosion in West Virginia, safety board concludes.
Big Pharma Goes Back To School p. 8
Partnerships: Sanofi, Johnson & Johnson are latest firms to ink research pacts.
Tagging Cholesterol p. 8
Chemical Biology: Click chemistry helps label cholesterylated proteins.
Enzymatic Revelation p. 9
Structural Biology: Structure provides insight into sugar-transferring enzyme.
GlaxoSmithKline Take A Big Hit p. 9
Firm announces $3.5 billion charge to cover lawsuits, investigation of marketing practices.
Praise For Obama's Rules Review p. 10
Federal Policy: Industry endorses President's directive on federal regulations.
Giving DNA A Good Yank p. 10
Biophysics: Find adds fodder to question about nature of overextended DNA.
Surprising Superoxide p. 11
Catalysis: Novel mode of end-on oxygen binding discovered in palladium complexes.
African Chemists Meet In Johannesburg p. 11
International: Conference draws 500 people with themes of chemistry and Africa's future, sustainability.
Business
Using Pore Power pp. 20-21 (Member Content)
New zeolite technologies help refiners crack crude and trucks clean up emissions.
Stimulus Program Underwhelms p. 22 (Member Content)
Small pharma firms cite government's glaring underestimation of the response to a $1 billion program.
Business Concentrates pp. 18-19 (Member Content)
- Cargill Divests Mosaic Stake
- Agricultural giant Cargill will divest its 64% stake in fertilizer maker Mosaic...
- Plastic Logic Gets Russian Investment
- Plastic Logic, a Mountain View, Calif.-based printed-electronics start-up, has inked a deal with...
- Kuraray Will Boost Resin In Germany
- Japan’s will spend $78 million to expand its polyvinyl alcohol resin plant...
- Toray Invests In Asian Carbon Fiber
- Toray Industries will build the first carbon fiber facility in South Korea. With a production capacity of 2,200 metric tons per year...
- Singapore Will Get Another Rubber Plant
- Japan’s Zeon Corp. will build an 80,000-metric-ton-per-year solution-polymerized styrene butadiene rubber (S-SBR) plant in Singapore...
- Vertellus Enters Indian Sulfone Market
- Vertellus Specialties is forming a joint venture with India’s Vapi Products Industries to make and market...
- Novacap Is Moving From Bain To AXA
- AXA Private Equity has agreed to acquire a majority stake in France’s Novacap from Bain Capital...
- Nanotech Ventures Get New Owners
- To focus on its nanomedicine start-ups, Arrowhead Research has sold Unidym, its carbon nanotube technology subsidiary...
- Evergreen To Close U.S. Solar Plant
- Evergreen Solar will shutter its solar wafer manufacturing plant in Devens, Mass., by the end of the first quarter...
- Molecular Profiles Invests In U.K. Site
- The British pharmaceutical services firm Molecular Profiles plans to add manufacturing capacity that will allow...
- Merck Serono, Domain Join For Parkinson's
- Merck Serono and Domain Therapeutics will jointly develop allosteric modulators of mGluR4...
- Genzyme Will Build A New Enzyme Plant
- Genzyme will spend some $335 million to build a manufacturing plant at its Geel, Belgium, site for alglucosidase alfa...
- Boehringer Ingelheim Acquires And Divests
- Boehringer Ingelheim will acquire Amgen’s biologic manufacturing facility in Fremont, Calif., and...
- Business Roundup
- DSM, Air Liquide, Rhodia, Materia, LanzaTech, Allos Therapeutics...
Career & Employment
Research Renaissance pp. 48-50
Despite challenges, scientist-educators flourish where arts and sciences mingle.
Awards
2011 ACS National Award Winners pp. 36-40 (Member Content)
Recipients are honored for contributions of major significance to chemistry.
- ACS Award In Polymer Chemistry
- ACS Award In Colloid & Surface Chemistry
- ACS Award In Pure Chemistry And National Fresenius Award
- ACS Award For Creative Work In Synthetic Organic Chemistry
- George A. Olah Award In Hydrocarbon Or Petroleum Chemistry
- Ronald Breslow Award For Achievement In Biomimetic Chemistry
- Charles Lathrop Parsons Award
- ACS Award For Achievement In Research For The Teaching & Learning Of Chemistry
Government & Policy
Transforming Deep-Sea Drilling pp. 24-26 (Member Content)
BP spill commission calls for sweeping changes in industry practices, federal regulation.
Industry Applauds Korean Trade Deal pp. 27-28 (Member Content)
Trade is as an area of potential collaboration between Obama and empowered Republicans.
Preaching Convergence p. 29 (Member Content)
Deeper integration of disciplines would benefit science, in particular biomedical research, MIT paper posits.
Government & Policy Concentrates p. 23 (Member Content)
- DOE Scientist To Run Offshore Oil Panel
- Thomas O. Hunter, former director of Sandia National Laboratories, will lead a new independent science board...
- Feds To Examine Freight Rail Pricing
- Federal regulators say they will consider new policy initiatives that could make it easier for chemical manufacturers...
- Disclosure Sought On Drilling Chemicals
- Democrats in the House of Representatives are supporting the Department of the Interior’s plan to require...
- Radiation Screening Program Faulted
- Using new advanced spectroscopic radiation detector systems proposed by the Department of Homeland Security to detect...
- FDA Revamps Medical Device Reviews
- FDA released a plan on Jan. 19 to overhaul how the agency approves medical devices under its 510(k) review process...
» more government & policy news...
People
Obituaries pp. 46-47 (Member Content)
Social Networking And C&EN
You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.
This Week Online
Science & Technology
Shotgun Approach To Drugs pp. 32-33 (Member Content)
Pacifichem News: Polypharmacology gives rise to drugs with multiple targets.
Science & Technology Concentrates pp. 30-31 (Member Content)
- Knockout Pictures
- X-ray structures of general anesthetics binding to an ion channel could aid search for new anesthetics.
- Death By Reduction
- Chemical Biology: A cysteine-rich defensin peptide turns antimicrobial when reduced.
- Glutamine Probe Images Tumors
- Scientists could use the 18F-glutamine derivatives to track tumors that use glutamine as an alternative energy source.
- Bringing Disorder To Titanium Dioxide
- Change allows the photocatalyst to absorb beyond the ultraviolet range, into visible and infrared spectrum.
- Relativity Powers Batteries
- Lead-acid car batteries’ power stems from relativistic effects.
» more science & technology news...
Education
Switching To Green pp. 34-35
UC Berkeley continuing education program helps professionals add green chemistry to their résumés.
Meetings
Fall 2011 ACS National Meeting pp. 41-45 (Member Content)
Divisions issue calls for papers for the Aug. 28–Sept. 1 meeting in Denver.
2011 C&EN Calendar Web Exclusive
C&EN's latest list of meetings and events of interest to those in the chemical community.
Editor's Page
A Program To Emulate p. 3
The Departments
Letters pp. 4-5
Newscripts p. 56
How Cats Lap, Periodic Table On A Hair (With Videos)
C&EN Archives
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Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives
Environmental SCENE News
Fertilizer May Help Bacteria Slip Into Groundwater
Water Safety: High phosphate levels allow deadly microbes to pass through soil.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Sunlight Is An Effective Disinfectant
Public Health: Field work shows that a cheap water treatment method improves children's health.
House Takes Aim At Clean Air Act
Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.
Analytical SCENE News
New Method Isolates Membrane Proteins
Protein Purification: Technique separates proteins on a lipid bilayer.
Bisphenol A Is Ubiquitous In Receipts
Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.
Mapping Drugs In Human Tissue
Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.
Skeletons Come To Light
Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.
Analyzing Nuclear Processes
ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.
JACS Research In C&EN
Indole Changeup Yields Elusive Alkaloid
ACS Meeting News: Cyclization and nitrene insertion star in synthesis.
Prefab Synthesis Moves Ahead
Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.
Multiple Bradykinin States Revealed
The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.
Scaling Up The Axinellamines
A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.
A Revamped Vancomycin
Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.
CENtral Science
» News, notes, and musings from C&EN
Check out some of the recent posts from C&EN's blog, "C&ENtral Science"
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