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Vetting The Data
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Quote of the Week

"We consider synthetic chemistry to be very outsourceable. Frankly, we don't do any of it in-house anymore."
KERRY L. SPEAR, VICE PRESIDENT OF MEDICINAL CHEMISTRY, SUNOVION PHARMACEUTICALp. 48

May 9, 2011

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Highlights

Cover Story

New Health Research Frontiers

As new genome sequencing technology debuts, pharma researchers step up to challenge of data analysis, frequently in data-sharing consortia. (pp. 17-21)

» More on this story
Business

Top 50 U.S. Chemical Producers (Member Content)

With the recession behind it, U.S. chemical industry girds for growth. (pp. 26-29)

Science & Technology

Saving Space Suits

Conservators try to stop the degradation of NASA's outer space outfits. (pp. 40-41)

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Table of Contents

Cover Story

The Next Generation In Genome Sequencing pp. 17-21

Advances in technology create new challenges in data analysis.

Research At The Heretical Edge pp. 22-23

Johnson & Johnson shares a cloud-hosted data management system with its brethren in big pharma.

News Of The Week

Jolting The Diels-Alderase Hunt p. 11

Biochemistry: Newly discovered enzyme could help chemists determine whether Diels-Alder reaction occurs in nature.

Albemarle To Make Lithium p. 12

New Technology: Company claims advance will allow recovery of lithium from Arkansas brine.

Appeals Court Overturns Stem Cell Research Injunction p. 12

Legal: Appeals court says federal funding may continue for work involving human embryonic stem cells while lower-court case proceeds.

Israel's Teva Will Acquire Cephalon p. 13

Pharmaceuticals: Generic drug giant to buy top biopharmaceutical firm.

Energy Department's Patent Sale p. 13

Agency offers deep discounts to spur start-ups to exploit technology developed by national labs.

Porous Polymer Captures CO2 p. 14

Materials: Tetrazole groups in new material selectively snag greenhouse gas.

Academy Elects New Members p. 14

Honors: Ninety scientists join the ranks of the National Academy of Sciences.

Firm Fined For Chemist's Death p. 15

Safety: Sepracor Canada admits lack of lab ventilation in worker fatality case.

Endosulfan Banned Worldwide p. 15

Persistent Pollutants: Certain uses of pesticide can continue until 2017.

Business

Top 50 U.S. Chemical Producers pp. 26-29 (Member Content)

With the recession behind it, U.S. chemical industry girds for growth.

Caveats Temper India's Promise pp. 30-31 (Member Content)

Chemical market grows strongly, but country remains a difficult place to do business.

The New Millipore p. 32 (Member Content)

Linked to Germany's Merck, laboratory tools maker expects to bolster services for the pharmaceutical industry.

Business Concentrates pp. 24-25 (Member Content)

This Week Online

Simplifying Pigment Detective Work

Art Conservation: Scientists remove a strong acid treatment in a Raman spectroscopy technique for measuring paint composition.

Watching Garlic Slay Bacteria

Food Science: Spectroscopy reveals bacterial downfall at the hands of garlic.

What Is Chemical Biology?

CENtral Science blogger Sidechain Bob starts a series of posts about the many faces of chemical biology with a look at peptidomimetics.

Examining Anesthetics

Scientists are just beginning to understand the molecular details of anesthesia, which puts an obstacle in the hunt for new and better anesthetic drugs.

Government & Policy

Industry Touts Free-Trade Deals pp. 35-36 (Member Content)

Pact with Colombia would immediately remove tariffs on most U.S. chemical exports.

EPA-Favored Cleaning Products p. 37 (Member Content)

Disclosure is now part of requirements for use of agency's logo on product labels.

Government & Policy Concentrates p. 34 (Member Content)

Education

C&EN Talks With David J. Asai p. 44

HHMI education director discusses coming changes in institute’s education funding.

Meetings

42nd Central Regional Meeting pp. 45-46 (Member Content)

Western Regional Meeting Call For Papers p. 47 (Member Content)

2011 C&EN Calendar Web Exclusive

C&EN's latest list of meetings and events of interest to those in the chemical community.

Facebook

Social Networking And C&EN

Social Networking And C&EN

You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.

Science & Technology

Saving Space Suits pp. 40-41

Conservators try to stop the degradation of NASA's outer space outfits. With Photo Gallery

Making Connections At NOBCChE pp. 42-43

Two students seek answers to career questions at annual meeting of black chemists and chemical engineers. With Photo Gallery

NOBCChE's 2011 Science Bowl And Fair Web Exclusive

Middle and high school students from Michigan dominate competitions at this year's meeting. With Photo Gallery And Video

Science & Technology Concentrates pp. 38-39

Career & Employment

Managing Outsourcing pp. 48-51

In drug and biotech firms, chemists are working to get more bang out of the CRO buck.

Editor's Page

Nuclear Power p. 5

The Departments

Letters pp. 6-9

Newscripts p. 56

Fresher Urinals, Cancer-Sniffing Dog

C&EN Archives

C&EN Archives

Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.

Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives

Environmental SCENE News

Fertilizer May Help Bacteria Slip Into Groundwater

Water Safety: High phosphate levels allow deadly microbes to pass through soil.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Sunlight Is An Effective Disinfectant

Public Health: Field work shows that a cheap water treatment method improves children's health.

House Takes Aim At Clean Air Act

Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.

Analytical SCENE News

New Method Isolates Membrane Proteins

Protein Purification: Technique separates proteins on a lipid bilayer.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Mapping Drugs In Human Tissue

Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.

Skeletons Come To Light

Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.

Analyzing Nuclear Processes

ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.

JACS Research In C&EN

Indole Changeup Yields Elusive Alkaloid

ACS Meeting News: Cyclization and nitrene insertion star in synthesis.

Prefab Synthesis Moves Ahead

Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.

Multiple Bradykinin States Revealed

The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.

Scaling Up The Axinellamines

A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.

A Revamped Vancomycin

Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.

CENtral Science

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


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