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Going It Alone
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Quote of the Week

"We understand that we have to be regulated. We just ask that it be fact-based and scientifically based."
CRAIG O. MORRISON, CEO, MOMENTIVE PERFORMANCE MATERIALSp. 23

June 20, 2011

In This Issue:

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October 24, 2011 Issue
October 17, 2011 Issue
October 10, 2011 Issue
October 3, 2011 Issue

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Highlights

Cover Story

After The Break-Up

The end of a partnership with big pharma brings both opportunity and challenge for biotech firms. (pp. 15-20)

Government & Policy

Jeremy Berg's Legacy At NIH (Member Content)

NIGMS director, champion of chemistry leaves an indelible mark. (pp. 28-30)

Science & Technology

Thermoelectrics Make A Comeback

New concepts and materials invigorate a commercially active but obscure field specializing in heating, cooling, and power generation. (pp. 33-35)

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Table of Contents

News Of The Week

Formaldehyde, Styrene Added To Cancer Warning List p. 11

Toxicology: Government recommends limited exposure to the industrial chemicals.

Supreme Court Backs Strong Patents p. 12

Intellectual Property: Justices uphold high hurdle for proving a patent is invalid.b.

Biotech Sector Rebounds p. 12

Pharmaceuticals: Recovery is occurring but growth is slow, dogged by a widening gap in access to capital.

Structure Of Brassinolide's Receptor Solved p. 13

Biochemistry: First look at sensor for plant hormone has implications for crop yield, protection.

Merck Moves Again On Biosimilars p. 13

Pharmaceuticals: Deal with South Korea's Hanwha adds generic version of Amgen's Enbrel to its portfolio.

Promising Pom-Poms p. 14

Therapeutics: Nucleic acid structures enter cells readily, control gene expression.

Olympians Of Chemistry p. 14

Four high school students will represent the U.S. at the International Chemistry Olympiad next month in Turkey.

Business

An Industry Resurgent p. 23 (Member Content)

Chemical executives at annual meeting revel in good times, stay wary on regulations.

Clariant Tells Its Story pp. 24-25 (Member Content)

Company leaders discuss outlook, as well as the Süd-Chemie acquisition, at a London event.

Porton Matures p. 26 (Member Content)

China-based custom intermediates producer enters active drug ingredients market.

Business Concentrates p. 22 (Member Content)

ACS News

CAS Registry Marks A Milestone p. 38 (Member Content)

2010 ACS Annual Report Now Online p. 38 (Member Content)

Carmen Giunta Is HIST's New Editor p. 38 (Member Content)

Print On Demand Available For ACS Journalse p. 38 (Member Content)

'Jeopardy!' To Feature IYC Questions p. 38 (Member Content)

This Week Online

New Method Pinpoints Synergistic Botanical Compounds

Natural Products: Researchers identify molecules in goldenseal that work together to kill bacteria.

Detecting Toxins from Freshwater Algae

Water Pollution: A Raman spectroscopy technique could lead to a simple field test for algal toxins.

A Simple Test Spots Bacteria

Biosensors: A strip of filter paper changes color when exposed to bacteria.

CENtral Science Blog: Yesteryear's Poisonous Prescriptions

Government & Policy

Jeremy Berg's Legacy At NIH pp. 28-30 (Member Content)

NIGMS Director, Champion Of Chemistry leaves an indelible mark.

Insights: NSF Takes A Hit p. 31 (Member Content)

Report on alleged waste and abuse at NSF only politicizes the agency.

Government & Policy Concentrates p. 27 (Member Content)

Awards

People

Promotions p. 43 (Member Content)

Facebook

Social Networking And C&EN

Social Networking And C&EN

You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.

Science & Technology

Thermoelectrics Make A Comeback pp. 33-35 (Member Content)

New concepts and materials invigorate a commercially active but obscure field specializing in heating, cooling, and power generation.

New And Notable At ASMS pp. 36-37 (Member Content)

Companies launch a variety of new instruments.

Science & Technology Concentrates p. 32

Meetings

Southeast Regional Meeting Call For Papers p. 41 (Member Content)

The 63rd Southeastern Regional Meeting (SERMACS 2011), hosted by the Virginia Section of the American Chemical Society, will take place on Oct. 26–29.

2011 C&EN Calendar Web Exclusive

C&EN's latest list of meetings and events of interest to those in the chemical community.

Editor's Page

Archives Excursion p. 5

The Departments

Letters pp. 4, 6-8

Newscripts p. 48

Melon Mines, Bear Scare, Dog Days.

C&EN Archives

C&EN Archives

Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.

Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives

Environmental SCENE News

Fertilizer May Help Bacteria Slip Into Groundwater

Water Safety: High phosphate levels allow deadly microbes to pass through soil.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Sunlight Is An Effective Disinfectant

Public Health: Field work shows that a cheap water treatment method improves children's health.

House Takes Aim At Clean Air Act

Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.

Analytical SCENE News

New Method Isolates Membrane Proteins

Protein Purification: Technique separates proteins on a lipid bilayer.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Mapping Drugs In Human Tissue

Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.

Skeletons Come To Light

Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.

Analyzing Nuclear Processes

ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.

JACS Research In C&EN

Indole Changeup Yields Elusive Alkaloid

ACS Meeting News: Cyclization and nitrene insertion star in synthesis.

Prefab Synthesis Moves Ahead

Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.

Multiple Bradykinin States Revealed

The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.

Scaling Up The Axinellamines

A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.

A Revamped Vancomycin

Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.

CENtral Science

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


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