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Quote of the Week

"This is our fifth report where the annual change in female leadership remained flat. If this trend line represented a patient's pulse, she'd be dead."
ILENE H. LANG, PRESIDENT, CATALYSTp. 22

August 8, 2011

In This Issue:

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October 24, 2011 Issue
October 17, 2011 Issue
October 10, 2011 Issue
October 3, 2011 Issue

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Highlights

Cover Story

Instrumental Efforts

Entrepreneurs take big risks to bring the latest scientific tools to market. (pp. 14-19)

» Repeat Start-Up: Entrepreneurial Scientist Perseveres Despite Setbacks.
Science & Technology

A Puzzle Named Bengü Sezen

A historic case of fraud in the chemistry community leaves many questions and issues unresolved. (pp. 40-43)

Science & Technology

Scrutinizing Sunscreens

Lotions containing inorganic nanoparticles draw attention of toxicologists and ire of some consumer groups. (pp. 44-46)

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Table of Contents

News Of The Week

Business Slows In Europe p. 9

Chemicals: Second-quarter results are better than last year's, but firms see demand softening.

More Merck Job Cuts p. 10

Pharmaceuticals: Drug maker heralds a second round of layoffs despite strong second quarter.

Prenylation With A Twist p. 10

Biochemistry: Enzyme catalyzes attachment of hydrophobic modifier to peptides in a new way.

Patenting Human Genes p. 11

Innovation: Appeals court overturns ban on gene patents; biotech industry scores victory.

Formosa Plastics Feels The Heat p. 11

Taiwan's government orders shutdown of group's fire-plagued Mailiao petrochemical facility.

Looking Past Yucca Mountain p. 12

Nuclear Waste: Blue-ribbon panel calls for interim storage of spent fuel.

Science And The Debt Deal p. 12

Politics: Compromise includes cuts that will hit science agencies over the next decade.

Graphene From Garbage p. 13

Materials: Low-value, impure carbon sources yield high-quality graphene.

Heavy-Metal Ring Bags Metal Atom p. 13

Inorganic Chemistry: Heterocycle traps an uncharged palladium atom in an odd host-guest interaction.

Business

Women in Industry pp. 22-23 (Member Content)

Women show marginal gains in this year’s edition of the C&EN survey of female executives.

Indian Firms Spread Their Wings pp. 24-27 (Member Content)

Acquisitions of Western assets demonstrate confidence on global stage.

Taking A Big Step In Virtual Space pp. 28-29 (Member Content)

Schrödinger counts on new investments to help it increase the impact of computational chemistry on drug discovery.

Business Concentrates pp. 20-21 (Member Content)

This Week Online

Proteins Reveal Their Secrets Under Pressure

NMR Spectroscopy: New device allows chemists to apply pressure to proteins during NMR experiments.

Beating Trypanosomes

Aaron Rowe describes promising drugs that attack trypanosomes, the protozoans responsible for Chagas, and the related disease sleeping sickness.

What's In A Name?

Carmen Drahl reveals the human side of chemistry through the stories of naming these elements and a few Nobel Prize-winning reactions.

MRI Machines Make Music

Transform the annoyingly loud banging of MRI machine noises into tunes like "Smoke on the Water."

Government & Policy

Barriers To Federal Tech Transfer pp. 32-34 (Member Content)

Regulations, policies impede commercialization of research from federal labs.

Commitments Are Running Out p. 36 (Member Content)

Possibilities for new global climate treaty are slim.

Government & Policy Concentrates p. 30 (Member Content)

  • NSF Pushes Tech Transfer
  • NSF has launched a new program to encourage team-based efforts to translate basic research results into marketable applications...
  • EPA Requires More Chemical Data
  • Chemical manufacturers will have to supply more data to EPA about the quantity and use of substances they make...
  • U.S. To Regulate Ammonium Nitrate
  • The Department of Homeland Security (DHS) is proposing to regulate the sale and transfer of ammonium nitrate in an effort to keep the potentially dangerous chemical out of the hands...
  • Dow Settles Pollution Case
  • Dow Chemical will pay $2.5 million to settle alleged pollution due to leaking pipes and valves at its facility in Midland, Mich....
  • House Panel Moves Biodefense Bill
  • The House of Representatives Energy & Commerce Committee has endorsed legislation that would reauthorize and fine-tune a 2006 law aimed at making sure the federal government is...

ACS Comment

Paying It Forward On Jobs: Members Helping Members p. 52 (Member Content)

ACS News

From The Lab To Capitol Hill pp. 54-55

ACS’s public policy fellows bring chemistry to Congress.

Awardees: ACS Welcomes New Congressional Fellows. p. 55

2011 ACS Fellows pp. 58-60

Society honors 213 members in the third year of its fellows program.

Facebook

Social Networking And C&EN

Social Networking And C&EN

You can now follow C&EN on Facebook. Become a fan and track the latest news and discussions at facebook.com/CENews.

Science & Technology

A Puzzle Named Bengü Sezen pp. 40-43

A historic case of fraud in the chemistry community leaves many questions and issues unresolved.

Scrutinizing Sunscreens pp. 44-46

Lotions containing inorganic nanoparticles draw attention of toxicologists and ire of some consumer groups.

Biopharma Joins The Doping Battle pp. 48-50 (Member Content)

Companies team up with international drug agency to curb athletes’ use of performance-enhancing drugs.

Science & Technology Concentrates pp. 38-39

Meetings

Final Program: 242nd ACS National Meeting

Denver, Aug. 28–Sept. 1.

2011 C&EN Calendar Web Exclusive

C&EN's latest list of meetings and events of interest to those in the chemical community.

Editor's Page

Sezen, Sames, and Columbia p. 5

The Departments

Letters pp. 6-7

Newscripts p. 96

Backyard Gas, Crafty Chemistry

C&EN Archives

C&EN Archives

Now the history of the chemical enterprise is instantly accessible online. C&EN Archives holds the complete collection of C&EN issues dated back from 1923, covering world chemical events, breakthroughs in research, technological advances, business and marketing ventures, government policy, career and education trends, and ACS milestones. With more than 500,000 pages of content, C&EN Archives is instantly accessible and fully searchable, allowing you to discover how the chemical enterprise developed into what it is today.

Head here to discover the past via the C&EN Archives, go to http://pubs.acs.org/cen-archives

Environmental SCENE News

Fertilizer May Help Bacteria Slip Into Groundwater

Water Safety: High phosphate levels allow deadly microbes to pass through soil.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Sunlight Is An Effective Disinfectant

Public Health: Field work shows that a cheap water treatment method improves children's health.

House Takes Aim At Clean Air Act

Pollution: Industry backs cost-benefit analyses of EPA rules, but critics fear assault on public health.

Analytical SCENE News

New Method Isolates Membrane Proteins

Protein Purification: Technique separates proteins on a lipid bilayer.

Bisphenol A Is Ubiquitous In Receipts

Endocrine Disrupters: Researchers detect BPA in every receipt that they collected from seven U.S. cities.

Mapping Drugs In Human Tissue

Clinical Chemistry: Mass spectrometry imaging provides view of an inhaled drug in human lung tissue.

Skeletons Come To Light

Fluorescence Imaging: Monitoring cells as they dissolve bone may lead to disease treatments.

Analyzing Nuclear Processes

ACS Meeting News: Analytical chemists devise ways to watch radioactive streams.

JACS Research In C&EN

Indole Changeup Yields Elusive Alkaloid

ACS Meeting News: Cyclization and nitrene insertion star in synthesis.

Prefab Synthesis Moves Ahead

Organic Chemistry: First stable alpha-boryl aldehydes ease preparation of complex small molecules.

Multiple Bradykinin States Revealed

The peptide adopts at least 10 conformers in solution, explaining why its structure had only been partially characterized.

Scaling Up The Axinellamines

A quicker, more efficient, and stereocontrolled route to a key intermediate streamlines natural product syntheses.

A Revamped Vancomycin

Medicinal Chemistry: Modified compound shows promise against hard-to-treat bacteria.

CENtral Science

» News, notes, and musings from C&EN

Check out some of the recent posts from C&EN's blog, "C&ENtral Science"


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